Filtered By:
Condition: Motor Neurone Disease

This page shows you your search results in order of relevance. This is page number 7.

Order by Relevance | Date

Total 256 results found since Jan 2013.

Corticospinal tract: a new hope for the treatment of post-stroke spasticity
AbstractStroke is the third leading cause of death and disability worldwide. Post-stroke spasticity (PSS) is the most common complication of stroke but represents only one of the many manifestations of upper motor neuron syndrome. As an upper motor neuron, the corticospinal tract (CST) is the only direct descending motor pathway that innervates the spinal motor neurons and is closely related to the recovery of limb function in patients with PSS. Therefore, promoting axonal remodeling in the CST may help identify new therapeutic strategies for PSS. In this review, we outline the pathological mechanisms of PSS, specifically ...
Source: Acta Neurologica Belgica - September 13, 2023 Category: Neurology Source Type: research

Peg tube insertion in neurodegenerative disease
Conclusion This study highlights the relatively high risk of PEG tube placement in patients with neurodegenerative disease. We present a number of points for consideration with the aim of improving the outcome in this particularly vulnerable group of patients.
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Sarkar, P., Cole, A., Scolding, N., Rice, C. Tags: Dementia, Drugs: CNS (not psychiatric), Stroke, Memory disorders (psychiatry) ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Pedaling improves gait ability of hemiparetic patients with stiff-knee gait: fall prevention during gait
Upper motor neuron lesions following the onset of stroke lead to disordered sensory-motor control causing intermittent or sustained involuntary muscle activation.1 In association with this abnormal central control of muscle activity, patients with stroke frequently develop stiff-knee gait characterized by reduced flexion of the knee joints during the swing phase.2,3 This condition impairs foot clearance, leading to toe dragging and increased risk of falls4. It has been widely reported that the specific cause of stiff-knee gait is the inappropriate activity of the rectus femoris.
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Kazuki Fujita, Yasutaka Kobayashi, Hiroichi Miaki, Hideaki Hori, Yuichi Tsushima, Ryo Sakai, Tomomi Nomura, Tomoki Ogawa, Hirotaka Kinoshita, Tomoko Nishida, Masahito Hitosugi Source Type: research

A case of aphemia following non-dominant sub-insular stroke: unveiling the Foix-Chavany-Marie phenomenon
Neurocase. 2021 Jun 27:1-6. doi: 10.1080/13554794.2021.1933541. Online ahead of print.ABSTRACTAphemia refers to the clinical syndrome of inability to orally produce speech with intact comprehension and written expression. Aphemia has been primarily reported in dominant frontal lobe strokes resulting in apraxia of speech (AoS), and in Foix-Chavany-Marie (FCM) syndrome where bilateral opercular or sub-opercular lesions result in anarthria due to deafferentation of brainstem nuclei supplying the oro-facio-lingual and pharyngeal musculature. Aphemia is not reported in non-dominant sub-insular strokes. Here, we present a case o...
Source: Neurocase - June 28, 2021 Category: Neurology Authors: Saurav Das Whitney Postman Michael A Haboubi Ozan Akca Kerri Remmel Alexandre R Carter Allyson Zazulia Source Type: research