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Condition: Heart Valve Disease

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Total 554 results found since Jan 2013.

Early and Late Outcomes After Minimally Invasive Mitral Valve Repair Surgery.
CONCLUSION: These data are the first from the U.K. demonstrating early and late outcomes after thoracoscopic assisted minimally invasive mitral valve repair surgery. The data establish the safety and efficacy of the technique and, importantly, lend further support towards a prospective randomized comparison of minimally invasive versus conventional mitral valve repair surgery. PMID: 26897819 [PubMed - in process]
Source: Journal of Heart Valve Disease - February 25, 2016 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Myocardial and Cardiocirculatory Reserve in Asymptomatic Aortic Stenosis and Preserved Ejection Fraction.
CONCLUSION: Besides SWL and female gender, the EF after dobutamine as well as highest exercise stress intensity reached are helpful in determining the prognosis of asymptomatic patients with moderate-severe AS. PMID: 26897816 [PubMed - in process]
Source: Journal of Heart Valve Disease - February 25, 2016 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Valve Replacement for Moderate Aortic Stenosis in Octogenarians Undergoing Revascularization.
CONCLUSION: In-hospital mortality is higher for octogenarians undergoing CABG+AVR compared to those undergoing isolated CABG. In the present study, a 'prophylactic' AVR was justified in patients with moderate AS, and their increased mortality (versus isolated CABG) was congruent with a higher preoperative co-morbid risk profile. Excellent long- term symptom-free survival further justifies 'prophylactic' AVR in octogenarians undergoing CABG with coexistent moderate AS. PMID: 26897807 [PubMed - in process]
Source: Journal of Heart Valve Disease - February 25, 2016 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Imaging Techniques for Diagnosis of Thoracic Aortic Atherosclerosis.
Authors: Jansen Klomp WW, Brandon Bravo Bruinsma GJ, van 't Hof AW, Grandjean JG, Nierich AP Abstract The most severe complications after cardiac surgery are neurological complications including stroke which is often caused by emboli merging from atherosclerosis in the ascending aorta to the brain. Information about the thoracic aorta is crucial in reducing the embolization risk for both surgical open and closed chest procedures such as transaortic heart valve implantation. Several techniques are available to screen the ascending aorta, for example, transesophageal echocardiography (TEE), epiaortic ultrasound, TEE ...
Source: International Journal of Vascular Medicine - March 12, 2016 Category: Cardiology Tags: Int J Vasc Med Source Type: research

Mitral valve repair using robotic technology: Safe, effective, and durable
The most recent American College of Cardiology/American Heart Association heart valve guidelines recommend that prompt surgical correction of severe degenerative mitral valve regurgitation, ideally mitral valve repair, should be performed to decrease the risks of long-term mortality and heart failure risks associated with this condition. Mitral valve repair performed using a minimally invasive robotic approach can now be successfully carried out in nearly all cases of degenerative disease with very low risks of stroke or death.
Source: The Journal of Thoracic and Cardiovascular Surgery - February 22, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Rakesh M. Suri, Joseph A. Dearani, Tomislav Mihaljevic, W. Randolph Chitwood, Douglas A. Murphy, Alfredo Trento, Hoda Javadikasgari, Harold M. Burkhart, Wiley L. Nifong, Richard C. Daly, A. Marc Gillinov Tags: Expert opinion Source Type: research

Colibri Heart Valve looks to raise $25m Series C for TAVR device
Colibri Heart Valve is looking to raise a $25 million Series C for the ready-to-use replacement heart valve it’s developing and has already put $1.25 million into its coffers. Broomfield, Colo.-based Colibri is running a 1st-in-human trial of the transcatheter aortic valve replacement it’s developing, a pre-mounted, pre-crimped and pre-packaged device that’s designed to be shipped ready to use, according to its website. Colibri has said that patients enrolled in the study showed no observed stroke, no pacemaker implantations, virtually no paravalvular leak and a high retained average effective orifice ...
Source: Mass Device - March 29, 2016 Category: Medical Equipment Authors: Brad Perriello Tags: Funding Roundup Replacement Heart Valves Wall Street Beat Colibri Heart Valve Source Type: news

MassDevice.com +5 | The top 5 medtech stories for April 13, 2016
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. Toshiba partners with UCI to study potential brain damage in HS football players Toshiba said yesterday it is partnering with the University of California, Irvine to study possible brain damage incurred in high school football ...
Source: Mass Device - April 13, 2016 Category: Medical Equipment Authors: MassDevice Tags: News Well Plus 5 Source Type: news

Poor patient warfarin knowledge may increase risk of deadly side effects
Patients have poor knowledge of warfarin which may increase their risk of serious side effects, according to research. Warfarin is given to patients at increased risk of blood clots from conditions such as atrial fibrillation or a mechanical heart valve. It 'thins the blood' by slowing down the anticoagulation effect of vitamin K, thereby increasing the time it takes blood to clot and reducing the risk of stroke. Taking too much warfain raises the risk of bleeding.
Source: ScienceDaily Headlines - April 15, 2016 Category: Science Source Type: news

Thirty-day outcomes in patients at intermediate risk for surgery from the SAPIEN 3 European approval trial.
CONCLUSIONS: TF-TAVI using the SAPIEN 3 THV in patients at intermediate risk for surgery is associated with a very low risk of death and complications, including new pacemakers and paravalvular leaks. Although compelling, these initial results are being confirmed in larger global studies before expanding the indications for TAVI in severe aortic stenosis. PMID: 27290682 [PubMed - in process]
Source: EuroIntervention - June 14, 2016 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

An approach to a patient with infective endocarditis.
Authors: Hitzeroth J, Beckett N, Ntuli P Abstract Although infective endocarditis (IE) is relatively uncommon, it remains an important clinical entity with a high in-hospital and 1-year mortality. It is most commonly caused by viridans streptococci. Staphylococcus aureus is responsible for a malignant course of IE and often requires early surgery to eradicate. Other rarer causes are various bacilli, including the HACEK (Haemophilus, Actinobacillus,Cardiobacterium, Eikenella and Kingella spp.) group of organisms and fungi. The clinical presentation varies. Patients may present with a nonspecific illness, valve dysfu...
Source: South African Medical Journal - June 17, 2016 Category: African Health Tags: S Afr Med J Source Type: research

Improving outcomes: case-matched comparison of novel second-generation versus first-generation self-expandable transcatheter heart valves ADULT CARDIAC
DISCUSSION TF-TAVI was feasible and safe using this new type of nitinol-based THV. Superiority to the current generation of self-expanding THVs was achieved regarding post-interventional pressure gradients and EOA, severity of residual PVL and rate of PM implantation. Results set a promising quality standard for TF-TAVI with a self-expanding THV, but will have to be confirmed in a larger patient cohorts for further clinical evaluation.
Source: European Journal of Cardio-Thoracic Surgery - July 19, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Schaefer, A., Treede, H., Schoen, G., Deuschl, F., Schofer, N., Schneeberger, Y., Blankenberg, S., Reichenspurner, H., Schaefer, U., Conradi, L. Tags: History, Transplantation - heart, Basic research vascular ADULT CARDIAC Source Type: research

Complications after transfemoral transcatheter aortic valve replacement with a balloon ‐expandable prosthesis: The importance of preventative measures and contingency planning
Abstract Transcatheter aortic valve replacement (TAVR) with balloon‐expandable Edwards‐SAPIEN valve was superior to standard therapy in inoperable patients and non‐inferior to surgical aortic valve replacement in high surgical‐risk, but operable patients, with severe symptomatic aortic stenosis in the randomized controlled PARTNER trial. Since the first case of TAVR with a balloon‐expandable valve in 2002, several groups have reported their experience with balloon‐expandable valves with high‐procedural success. In the United States, the balloon‐expandable Edwards‐SAPIEN valve is the only transcatheter hea...
Source: Catheterization and Cardiovascular Interventions - February 20, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Tarun Chakravarty, Hasan Jilaihawi, Niraj Doctor, Gregory Fontana, James S. Forrester, Wen Cheng, Raj Makkar Tags: Clinical Decision Making Source Type: research

Atrial Fibrillation Patients Treated With Long-Term Warfarin Anticoagulation Have Higher Rates of All Dementia Types Compared With Patients Receiving Long-Term Warfarin for Other Indications Cardiovascular Surgery
Conclusions The presence of AF significantly increases risk of dementia, including Alzheimer's disease, compared with matched patients receiving warfarin anticoagulation for other reasons. Quality of anticoagulation management remains an important risk factor for dementia in all patients.
Source: JAHA:Journal of the American Heart Association - July 10, 2016 Category: Cardiology Authors: Bunch, T. J., May, H. T., Bair, T. L., Crandall, B. G., Cutler, M. J., Day, J. D., Jacobs, V., Mallender, C., Osborn, J. S., Stevens, S. M., Weiss, J. P., Woller, S. C. Tags: Arrhythmias, Electrophysiology, Atrial Fibrillation Cardiovascular Surgery Source Type: research

Zebrafish models of cardiovascular disease
AbstractCardiovascular disease (CVD) is one of the leading causes of death worldwide. The most significant risk factors associated with the development of heart diseases include genetic and environmental factors such as hypertension, high blood cholesterol levels, diabetes, smoking, and obesity. Coronary artery disease accounts for the highest percentage of CVD deaths and stroke, cardiomyopathies, congenital heart diseases, heart valve defects and arrhythmias follow. The causes, prevention, and treatment of all forms of cardiovascular disease remain active fields of biomedical research, with hundreds of scientific studies ...
Source: Heart Failure Reviews - August 7, 2016 Category: Cardiology Source Type: research

Experimental Validation of a Cardiac Simulator for in vitro Evaluation of Prosthetic Heart Valves
Conclusion: The experimental validation was performed, allowing, in future studies, characterizing the hydrodynamic performance of prosthetic heart valves.
Source: Revista Brasileira de Cirurgia Cardiovascular - August 19, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research