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Condition: Heart Disease
Procedure: Heart Valve Surgery

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Total 250 results found since Jan 2013.

Personalizing Medicine: Considering Preferences and Values
If you're interested in heart disease -- and who over the age of 40 isn't? -- you may have read an excellent series of articles by reporter Gina Kolata recently published in the New York Times. If you haven't seen it, the series includes pieces on blood pressure, stents, heart attack treatment and a new approach to aortic valve replacement. The heart valve article especially caught my eye, as this is a story I've been watching with personal interest: My 90-year-old mother has aortic stenosis for which surgery has been recommended. In fact, surgery was first recommended for my mom at least six years ago. I know that timing ...
Source: Healthy Living - The Huffington Post - July 10, 2015 Category: Consumer Health News Source Type: news

Evolution and prognostic impact of low flow after transcatheter aortic valve replacement
Conclusions The measurement of EP-SVi is useful to assess the immediate haemodynamic benefit of TAVR and to predict the risk of late mortality.
Source: Heart - July 9, 2015 Category: Cardiology Authors: Le Ven, F., Thebault, C., Dahou, A., Ribeiro, H. B., Capoulade, R., Mahjoub, H., Urena, M., Nombela-Franco, L., Allende Carrera, R., Clavel, M.-A., Dumont, E., Dumesnil, J., De Larochelliere, R., Rodes-Cabau, J., Pibarot, P. Tags: Drugs: cardiovascular system, Echocardiography, Clinical diagnostic tests, Epidemiology Valvular heart disease Source Type: research

Apixaban Compared with Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: Findings From the ARISTOTLE Trial.
CONCLUSIONS: -More than a quarter of the patients in ARISTOTLE with "nonvalvular" atrial fibrillation had moderate or severe valvular heart disease. There was no evidence of a differential effect of apixaban over warfarin in reducing stroke or systemic embolism, causing less bleeding, and reducing death in patients with and without valvular heart disease. Clinical Trial Registration Information-clinicaltrials.gov. Identifier: NCT00412984. PMID: 26106009 [PubMed - as supplied by publisher]
Source: Circulation - June 23, 2015 Category: Cardiology Authors: Avezum A, Lopes RD, Schulte PJ, Lanas F, Gersh BJ, Hanna M, Pais P, Erol C, Diaz R, Bahit MC, Bartunek J, De Caterina R, Goto S, Ruzyllo W, Zhu J, Granger CB, Alexander JH Tags: Circulation Source Type: research

Eating chocolate may slightly lower your risk of stroke
ConclusionThis study used a large prospective cohort of English residents to estimate the risk chocolate poses to cardiovascular death and disease. In addition, they systematically combed the research literature for other similar studies, combining their results with that of other researchers. By comparing the highest chocolate consumers with chocolate abstainers, they found that chocolate was linked to a lower risk of stroke and cardiovascular disease. The risk for coronary heart disease was not statistically significant. Results from the meta-analysis of eight additional studies showed higher chocolate consumption was li...
Source: NHS News Feed - June 16, 2015 Category: Consumer Health News Tags: Food/diet Heart/lungs Neurology Source Type: news

Paradoxical low-flow, low-gradient severe aortic stenosis: a distinct disease entity
Low-flow, low-gradient (LFLG) severe aortic stenosis (AS), despite preserved LVEF, that is, paradoxical LFLG, is one of the most challenging entities in valvular heart disease.1 Hachicha et al were the first to report that patients with small aortic valve area (AVA) and preserved LVEF may concomitantly have an LF and thus often low gradient.1 This new entity is defined as an AVA ≤1.0 cm2 or indexed AVA ≤0.6 cm2/m2, a mean pressure gradient (MPG) <40 mm Hg, an LVEF ≥50% and a stroke volume index (SVi) <35 mL/m2. The most recent European2 and American3 guidelines have recognised parado...
Source: Heart - June 10, 2015 Category: Cardiology Authors: Magne, J., Mohty, D. Tags: Drugs: cardiovascular system, Echocardiography, Aortic valve disease, Right sided valvular heart disease, Clinical diagnostic tests Editorials Source Type: research

Treating valvular heart disease has never been one size fits all
The case report by Capestro and colleagues in this issue of the Journal illustrates the many therapeutic options cardiac surgeons now have at their disposal to treat complex valvular heart disease.1 Capestro and colleagues have described a difficult patient scenario that occurs commonly after homograft implantation. The rate of structural valve deterioration with homografts approaches nearly 40% at 10 years, and the accompanying extensive calcification of these prostheses complicates reoperative aortic valve replacement surgery by predisposing toward paravalvular leaks, the implantation of small prostheses, and perioperative stroke.
Source: The Journal of Thoracic and Cardiovascular Surgery - June 5, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Hersh Maniar Tags: Editorial commentary Source Type: research

Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: the Global Rheumatic Heart Disease Registry (the REMEDY study)
Conclusion Rheumatic heart disease patients were young, predominantly female, and had high prevalence of major cardiovascular complications. There is suboptimal utilization of secondary antibiotic prophylaxis, oral anti-coagulation, and contraception, and variations in the use of percutaneous and surgical interventions by country income level.
Source: European Heart Journal - May 7, 2015 Category: Cardiology Authors: Zuhlke, L., Engel, M. E., Karthikeyan, G., Rangarajan, S., Mackie, P., Cupido, B., Mauff, K., Islam, S., Joachim, A., Daniels, R., Francis, V., Ogendo, S., Gitura, B., Mondo, C., Okello, E., Lwabi, P., Al-Kebsi, M. M., Hugo-Hamman, C., Sheta, S. S., Haile Tags: Valvular heart disease Source Type: research

Abstract 234: Comparison of Hospital Length of Stay and Costs between Non-valvular Atrial Fibrillation Patients Treated with Either Apixaban or Warfarin Session Title: Poster Session II
Conclusions: NVAF patients treated with apixaban had significantly shorter hospital LOS and lower index hospitalization costs compared to those treated with warfarin. Costs remained significantly lower for apixaban patients across all CHADS2 scores.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Xie, L., Vo, L., Keshishian, A., Price, K., Singh, P., Mardekian, J., Bruno, A., Baser, O., Kim, J., Tan, W., Trocio, J. Tags: Session Title: Poster Session II Source Type: research

Knowledge Regarding Oral Anticoagulation Therapy among Patients with Stroke and Those at High Risk of Thromboembolic Events (P6.241)
Conclusion- Patient’s knowledge about OAT was suboptimal. The findings support the need for educational interventions to improve the knowledge regarding oral anticoagulation therapy, and thereby achieve an appropriate and safe secondary prevention of stroke.Disclosure: Dr. Bhatia has nothing to disclose. Dr. Alphonsa has nothing to disclose. Dr. Sharma has nothing to disclose. Dr. Sharma has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Bhatia, R., Alphonsa, A., Sharma, K., Sharma, G. Tags: Cerebrovascular Disease and Interventional Neurology: Thrombolysis Complications Source Type: research

Effect of Left Ventricular Ejection Fraction on Postoperative Outcome in Patients With Severe Aortic Stenosis Undergoing Aortic Valve Replacement Valvular Heart Disease
Conclusions— LVEF is a powerful predictor of outcome in patients with severe aortic stenosis undergoing aortic valve replacement, independent of the presence of valve-related symptoms.
Source: Circulation: Cardiovascular Imaging - April 7, 2015 Category: Radiology Authors: Dahl, J. S., Eleid, M. F., Michelena, H. I., Scott, C. G., Suri, R. M., Schaff, H. V., Pellikka, P. A. Tags: Contractile function, Valvular heart disease, Echocardiography, CV surgery: valvular disease Source Type: research

Paravalvular regurgitation after transcatheter aortic valve replacement with the Edwards sapien valve in the PARTNER trial: characterizing patients and impact on outcomes
Conclusion Differences in baseline characteristics in patients with increasing severities of PVR may increase the risk of this complication. Despite these differences, multivariable analysis demonstrated that both mild and moderate/severe PVR predicted higher 1-year mortality.
Source: European Heart Journal - February 14, 2015 Category: Cardiology Authors: Kodali, S., Pibarot, P., Douglas, P. S., Williams, M., Xu, K., Thourani, V., Rihal, C. S., Zajarias, A., Doshi, D., Davidson, M., Tuzcu, E. M., Stewart, W., Weissman, N. J., Svensson, L., Greason, K., Maniar, H., Mack, M., Anwaruddin, S., Leon, M. B., Hah Tags: Valvular heart disease Source Type: research

Impact of exercise pulmonary hypertension on postoperative outcome in primary mitral regurgitation
Conclusions ExPHT is associated with increased risk of adverse cardiac events following mitral valve surgery in patients with primary MR.
Source: Heart - February 12, 2015 Category: Cardiology Authors: Magne, J., Donal, E., Mahjoub, H., Miltner, B., Dulgheru, R., Thebault, C., Pierard, L. A., Pibarot, P., Lancellotti, P. Tags: Drugs: cardiovascular system, Echocardiography, Hypertension, Mitral valve disease, Clinical diagnostic tests Valvular heart disease Source Type: research

Knowledge Regarding Oral Anticoagulation Therapy among Patients with Stroke and Those at High Risk of Thromboembolic Events
Apart from atrial fibrillation, indications for oral anticoagulation common in our clinical practice include rheumatic heart disease and mechanical heart valve replacement. Evaluation of current patient knowledge regarding oral anticoagulation therapy (OAT) is the first step in improving the quality of anticoagulation therapy and patient care. The aim of the present study was to assess the knowledge regarding OAT among patients with stroke and those at high risk of thromboembolic events in a tertiary care hospital in India.
Source: Journal of Stroke and Cerebrovascular Diseases - January 7, 2015 Category: Neurology Authors: Annu Alphonsa, Kamlesh K. Sharma, Gautam Sharma, Rohit Bhatia Source Type: research

Long-Term Results of Transapical Versus Transfemoral TAVI in a Real World Population of 1000 Patients With Severe Symptomatic Aortic Stenosis Structural Heart Disease
Conclusions— The data demonstrate that in an experienced multidisciplinary heart team, either access route can be performed with comparable results.
Source: Circulation: Cardiovascular Interventions - December 31, 2014 Category: Cardiology Authors: Schymik, G., Wurth, A., Bramlage, P., Herbinger, T., Heimeshoff, M., Pilz, L., Schymik, J. S., Wondraschek, R., Suselbeck, T., Gerhardus, J., Luik, A., Gonska, B.-D., Posival, H., Schmitt, C., Schrofel, H. Tags: CV surgery: valvular disease Structural Heart Disease Source Type: research

Aortic stenosis: flow matters
The presence of a low transvalvular pressure gradient (<40 mm Hg) in conjunction with a small aortic valve area (AVA ≤1 cm2) is a challenging situation as it raises uncertainty about the actual severity of aortic stenosis (AS) and therefore about the indication of aortic valve replacement (AVR) if the patient is symptomatic. This low-gradient ‘severe’ (small AVA) AS entity may in fact be related to: (i) measurement errors: underestimation of stroke volume (SV), AVA and/or gradient;S1 (ii) small body size: a small AVA in a small patient may correspond to moderate AS and low gradient; (iii) i...
Source: Heart - December 12, 2014 Category: Cardiology Authors: Pibarot, P. Tags: Drugs: cardiovascular system, Echocardiography, Hypertension, Aortic valve disease, Mitral valve disease, Right sided valvular heart disease, Clinical diagnostic tests, Epidemiology Editorials Source Type: research