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Condition: Heart Disease
Procedure: Heart Valve Surgery

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Total 250 results found since Jan 2013.

Transcatheter Aortic Valve Implantation Compared With Surgical Aortic Valve Replacement in Low-Risk Patients Structural Heart Disease
Conclusions— In patients with low operative risk, significantly better 3-year survival and freedom from major adverse cardiac and cerebrovascular events were observed after SAVR compared with TAVI. Further studies on new-generation valve prostheses are necessary before expanding indications of TAVI toward lower-risk patients.
Source: Circulation: Cardiovascular Interventions - May 5, 2016 Category: Cardiology Authors: Rosato, S., Santini, F., Barbanti, M., Biancari, F., DErrigo, P., Onorati, F., Tamburino, C., Ranucci, M., Covello, R. D., Santoro, G., Grossi, C., Ventura, M., Fusco, D., Seccareccia, F., on behalf of the OBSERVANT Research Group Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation, Mortality/Survival Structural Heart Disease Source Type: research

Validated Risk Score for Predicting 6-Month Mortality in Infective Endocarditis Valvular Heart Disease
Conclusions Six-month mortality after IE is 25% and is predicted by host factors, IE characteristics, and IE complications. Surgery during the index hospitalization is associated with lower mortality but is performed less frequently in the highest risk patients. A simplified risk model may be used to identify specific risk subgroups in IE.
Source: JAHA:Journal of the American Heart Association - April 17, 2016 Category: Cardiology Authors: Park, L. P., Chu, V. H., Peterson, G., Skoutelis, A., Lejko-Zupa, T., Bouza, E., Tattevin, P., Habib, G., Tan, R., Gonzalez, J., Altclas, J., Edathodu, J., Fortes, C. Q., Siciliano, R. F., Pachirat, O., Kanj, S., Wang, A., for the International Collaborat Tags: Clinical Studies, Infectious Endocarditis, Valvular Heart Disease, Mortality/Survival Source Type: research

Risk of death and stroke associated with anticoagulation therapy after mitral valve repair
Conclusion VKA treatment after mitral valve repair is associated with a markedly lower risk of adverse events as stroke or death without excess major bleeding risk during the first 3 months following surgery.
Source: Heart - April 11, 2016 Category: Cardiology Authors: Valeur, N., Merie, C., Hansen, M. L., Torp-Pedersen, C., Gislason, G. H., Kober, L. Tags: Drugs: cardiovascular system, Interventional cardiology, Epidemiology Valvular heart disease Source Type: research

Year in review: transcatheter aortic valve replacement
This article aims to review the most recent results and essential issues.
Source: Current Opinion in Cardiology - February 5, 2016 Category: Cardiology Tags: VALVULAR HEART DISEASE: Edited by Subodh Verma Source Type: research

Synergistic Utility of Brain Natriuretic Peptide and Left Ventricular Strain in Patients With Significant Aortic Stenosis Valvular Heart Disease
Conclusions In normal LVEF patients with significant aortic stenosis, BNP and LV-GLS provide incremental (additive not duplicative) prognostic information over established predictors, suggesting that both play a synergistic role in defining outcomes.
Source: JAHA:Journal of the American Heart Association - January 5, 2016 Category: Cardiology Authors: Goodman, A., Kusunose, K., Popovic, Z. B., Parikh, R., Barr, T., Sabik, J. F., Rodriguez, L. L., Svensson, L. G., Griffin, B. P., Desai, M. Y. Tags: Metabolism, Valvular Heart Disease, Echocardiography, Cardiovascular Surgery Source Type: research

Annual Outcomes With Transcatheter Valve Therapy From the STS/ACC TVT Registry
ConclusionsThe TVT Registry provides important information on characteristics and outcomes of TAVR in contemporary U.S. clinical practice. It can be used to identify trends in practice and opportunities for quality improvement.
Source: Journal of the American College of Cardiology - December 21, 2015 Category: Cardiology Source Type: research

At UCLA, it's medicine 2.0
Tucked deep in the basement of UCLA’s Center for the Health Sciences is a room that looks more like an inventor’s fantasy workshop than the medical research facility it is. Tables are piled high with tools, electronics, prototype equipment parts and a few stray robotic arms. Posters on the wall describe pending projects in dense technical language with accompanying photos of futuristic devices. This hidden space is where scientists are working at the very forefront of technological advances in medicine. Its assemblage of smarts, parts and computers is contributing to an emerging era of personalized, tech-enabled health...
Source: UCLA Newsroom: Health Sciences - December 16, 2015 Category: Universities & Medical Training Source Type: news

Annual Outcomes With Transcatheter Valve Therapy
Conclusions The TVT Registry provides important information on characteristics and outcomes of TAVR in contemporary U.S. clinical practice. It can be used to identify trends in practice and opportunities for quality improvement.
Source: The Annals of Thoracic Surgery - November 30, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

High intensity focused ultrasound ablation for atrial fibrillation: results from the National Spanish Registry.
CONCLUSIONS: The Spanish national registry showed an efficacy of AF ablation with the HIFU Epicor system of 66.1%, 63.8%, 63.9% and 45.9% at 6, 12, 24 and 36 months follow-up. There was no device-related complications. PMID: 26006216 [PubMed - as supplied by publisher]
Source: Minerva Cardioangiologica - November 18, 2015 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Four-year cardiac magnetic resonance (CMR) follow-up of patients treated with percutaneous pulmonary valve stent implantation
Conclusions CMR demonstrated restored pulmonary conduit function, reduced RV volumes and increased RV and LV function but did not predict valve fracture/restenosis. Key points • A CMR 4-year follow-up after PPVI showed restored pulmonary conduit function • RV volumes were significantly reduced • RV function was significantly better in terms of increased EF and SVI • LV function was significantly better in terms of inc...
Source: European Radiology - November 17, 2015 Category: Radiology Source Type: research

Procedural Results and Clinical Outcomes of Transcatheter Aortic Valve Implantation in Switzerland: An Observational Cohort Study of Sapien 3 Versus Sapien XT Transcatheter Heart Valves Structural Heart Disease
Conclusions— The use of the new generation S3 balloon-expandable THV reduced the risk of more than mild paravalvular regurgitation and vascular complications but was associated with an increased permanent pacemaker rate compared with the XT. Transcatheter aortic valve implantation using the newest generation balloon-expandable THV is associated with a low risk of stroke and favorable clinical outcomes. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01368250.
Source: Circulation: Cardiovascular Interventions - October 9, 2015 Category: Cardiology Authors: Binder, R. K., Stortecky, S., Heg, D., Tueller, D., Jeger, R., Toggweiler, S., Pedrazzini, G., Amann, F. W., Ferrari, E., Noble, S., Nietlispach, F., Maisano, F., Raber, L., Roffi, M., Grunenfelder, J., Juni, P., Huber, C., Windecker, S., Wenaweser, P. Tags: Catheter-based coronary and valvular interventions: other, CV surgery: valvular disease Structural Heart Disease Source Type: research

Replicating Patient-Specific Severe Aortic Valve Stenosis With Functional 3D Modeling Valvular Heart Disease
Conclusions— By combing the technologies of high-spatial resolution computed tomography, computer-aided design software, and fused dual-material 3D printing, we demonstrate that patient-specific models can replicate both the anatomic and functional properties of severe degenerative aortic valve stenosis.
Source: Circulation: Cardiovascular Imaging - October 8, 2015 Category: Radiology Authors: Maragiannis, D., Jackson, M. S., Igo, S. R., Schutt, R. C., Connell, P., Grande-Allen, J., Barker, C. M., Chang, S. M., Reardon, M. J., Zoghbi, W. A., Little, S. H. Tags: Catheter-based coronary and valvular interventions: other, CT and MRI, Echocardiography, CV surgery: valvular disease Valvular Heart Disease Source Type: research

Outcomes of Transcatheter Aortic Valve Implantation in High Surgical Risk and Inoperable Patients with Aortic Stenosis ‐ A Single Australian Centre Experience
ConclusionsTAVI with various valve systems, delivered via a number of approaches, is feasible in high surgical risk and inoperable patients with severe aortic stenosis, with acceptable outcomes at short‐ and intermediate‐term follow‐up.
Source: Internal Medicine Journal - October 1, 2015 Category: Internal Medicine Authors: Vijayakumar Subban, Dale Murdoch, Michael L Savage, James Crowhurst, Ramakrishna Saireddy, Karl K Poon, Alexander Incani, Nicholas Bett, Darryl J Burstow, Gregory M Scalia, Andrew Clarke, Owen Christopher Raffel, Constantine N Aroney, Darren L Walters Tags: Original Article Source Type: research

Watchful observation versus early aortic valve replacement for symptomatic patients with normal flow, low-gradient severe aortic stenosis
Conclusions Early AVR and watchful observation strategy show similar survival in symptomatic patients with normal flow, low-gradient severe AS and preserved LVEF. Watchful observation with timely performance of AVR should be considered a therapeutic option.
Source: Heart - August 12, 2015 Category: Cardiology Authors: Kang, D.-H., Jang, J. Y., Park, S.-J., Kim, D.-H., Yun, S.-C., Song, J.-M., Park, S. W., Chung, C.-H., Song, J.-K., Lee, J.-W. Tags: Drugs: cardiovascular system, Aortic valve disease, Epidemiology Valvular heart disease Source Type: research

How to define valvular atrial fibrillation?
Abstract Atrial fibrillation (AF) confers a substantial risk of stroke. Recent trials comparing vitamin K antagonists (VKAs) with non-vitamin K antagonist oral anticoagulants (NOACs) in AF were performed among patients with so-called "non-valvular" AF. The distinction between "valvular" and "non-valvular" AF remains a matter of debate. Currently, "valvular AF" refers to patients with mitral stenosis or artificial heart valves (and valve repair in North American guidelines only), and should be treated with VKAs. Valvular heart diseases, such as mitral regurgitation, aortic stenosis (AS) and aortic insufficiency, do...
Source: Archives of Cardiovascular Diseases - July 13, 2015 Category: Cardiology Authors: Fauchier L, Philippart R, Clementy N, Bourguignon T, Angoulvant D, Ivanes F, Babuty D, Bernard A Tags: Arch Cardiovasc Dis Source Type: research