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Condition: Heart Disease
Procedure: Heart Valve Surgery

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Total 250 results found since Jan 2013.

Spontaneous Spinal Epidural Hematoma in an Adult Patient with Complex Congenital Heart Disease
We report the case of a 27-year-old man who developed sudden upper back pain with no specific precipitant. Five days later, he visited our emergency department complaining of weakness in both lower limbs and dysuria. He had a history of intracardiac repair and a Blalock-Park procedure for an interrupted aortic arch and ventricular septal defect in infancy. Additionally, he had undergone an aortic root dilatation and aortic valve replacement at the age of 10 because of progression of aortic and supra-aortic stenosis and had received chronic anticoagulation and antiplatelet therapy with warfarin and aspirin, respectively. An...
Source: International Heart Journal - July 8, 2021 Category: Cardiology Authors: Toshinobu Ifuku Toshihiro Nishiguchi Source Type: research

Janssen Submits New Drug Application to U.S. FDA for XARELTO ® (rivaroxaban) to Help Prevent and Treat Blood Clots in Pediatric Patients
RARITAN, NJ, June 23, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for the use of XARELTO® (rivaroxaban) in pediatric patients. The NDA seeks two pediatric indications: treatment of venous thromboembolism (VTE, or blood clots) and reduction in the risk of recurrent VTE in patients aged birth to less than 18 years of age after at least five days of initial parenteral anticoagulant treatment; and thromboprophylaxis (prevention of blood clots) in patients aged 2 years and older with congenita...
Source: Johnson and Johnson - June 23, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Prognosis of paradoxical low-flow low-gradient aortic stenosis after transcatheter aortic valve replacement
Aims In paradoxical low-flow low-gradient severe aortic stenosis (PLFLG AS) patients, stroke volume index (SVI) is reduced despite preserved left ventricular ejection fraction (LVEF). Although reduced SVI is already known as a poor prognostic predictor, the outcomes of PLFLG AS patients after transcatheter aortic valve replacement (TAVR) have not been clearly defined. We retrospectively investigated the post-TAVR outcomes of PLFLG AS patients in comparison with normal-flow high-gradient aortic stenosis (NFHG AS) patients. Methods The current observational study included 245 patients with NFHG AS (mean transaorti...
Source: Journal of Cardiovascular Medicine - May 1, 2021 Category: Cardiology Tags: Research articles: Valvular heart disease Source Type: research

Commentary: In the era of mitral valve-in-valve therapy, mechanical prosthesis in young patients does not deserve to be forgotten
Chen and colleagues1 from Memorial Hospital of Taoyaun in Taiwan analyzed, retrospectively, the results of patients who received either biological or mechanical valve for mitral valve replacement in rheumatic heart disease. Patient data were extracted from the National Health Insurance administrative database in Taiwan. Propensity score analysis yielded 2 paired groups of 788 patients. No significant difference in terms of in-hospital mortality were observed between the 2 matched groups. Regarding late outcomes, all-cause mortality at 10  years was in favor of the mechanical valve group, risk of stroke tended to be higher...
Source: The Journal of Thoracic and Cardiovascular Surgery - April 1, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Francesco Formica, Francesco Maestri, Francesco Nicolini Tags: Commentary Source Type: research

Right mini ‐thoracotomy approach for grown‐up congenital heart disease
ConclusionsRight mini ‐thoracotomy cardiac surgery in selected patients with GUCH allows to avoid the big scar of the sternotomy approach and to accelerate the recovery in a young population. Moreover, in redo cases, it allows the surgeon to reach the heart and the aorta avoiding the well‐known risks of a re‐sterno tomy procedure.
Source: Journal of Cardiac Surgery - February 26, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Cristina Barbero, Giovanni Marchetto, Carlo Pace Napoleone, Claudia Calia, Erik Cura Stura, Marco Pocar, Mauro Rinaldi, Massimo Boffini Tags: ORIGINAL ARTICLE Source Type: research

How Common are Aortic Aneurysms?
Discussion Aortic root dilatation or thoracic aortic aneurysm occurs in 6:100,000 individuals > 50 years of age. It is due to aging, hypertension, hypercholesterolemia, and smoking. Tertiary syphilis was a cause in the preantibiotic era. Pediatric aneurysms are very uncommon but the exact prevalence is different due to the various causes. Aneurysms are due to genetic disorders, congenital anomalies or post-surgical repair. In pediatric patients with sudden cardiac deaths, 5.4% are due to ruptured thoracic aortic aneurysms. Learning Point Some causes of pediatric aneurysms include: Familial thoracic aneurysm and dissect...
Source: PediatricEducation.org - February 22, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Clinical Features and Outcome of Infective Endocarditis in a University Hospital in Romania
Conclusions: Staphylococcus aureus IE was associated with the presence of large vegetations, prosthetic valve endocarditis and intracardiac abscess. Coagulase negative Staphylococcus (CoNS) infection was associated with prosthetic valve dysfunction. Streptococcus gallolyticus etiology correlated with ischemic embolic stroke and the presence of large vegetations. Cardiovascular surgery was recommended in 67.4% of patients but was performed only on half of them. In hospital death occurred in 33.7% of patients and independent predictors of mortality were congestive heart failure and septic shock.PMID:33578787 | DOI:10.3390/medicina57020158
Source: Medicina (Kaunas) - February 13, 2021 Category: Universities & Medical Training Authors: Emilia Elena Babe ș Diana Anca Lucu ța Codru ța Diana Petcheși Andreea Atena Zaha Cristian Ilyes Alexandru Daniel Jurca Cosmin Mihai Vesa Dana Carmen Zaha Vlad Victor Babe ș Source Type: research