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Condition: Heart Disease
Procedure: Heart Valve Surgery

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Total 250 results found since Jan 2013.

Medication Management of Patients Undergoing Transcatheter Aortic Valve Replacement
This article summarizes key literature supporting the pharmacologic management of patients receiving TAVR. This article is protected by copyright. All rights reserved.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - November 9, 2017 Category: Drugs & Pharmacology Authors: Bethany A. Kalich, J. Erin Ledford, Ian B. Hollis Tags: Review of Therapeutics Source Type: research

Metoprolol Reduces Hemodynamic and Metabolic Overload in Asymptomatic Aortic Valve Stenosis Patients: A Randomized Trial Ventricular Structure and Function
Conclusions— In patients with asymptomatic AS, metoprolol increases systolic ejection time and reduces aortic valve gradients, global afterload, and myocardial oxygen requirements. Thus, metoprolol displays favorable hemodynamic and metabolic effects and could improve outcome in patients with asymptomatic AS. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT02076711.
Source: Circulation: Cardiovascular Imaging - September 27, 2017 Category: Radiology Authors: Hansson, N. H., Sorensen, J., Harms, H. J., Kim, W. Y., Nielsen, R., Tolbod, L. P., Frokiaer, J., Bouchelouche, K., Dodt, K. K., Sihm, I., Poulsen, S. H., Wiggers, H. Tags: Clinical Studies, Metabolism, Valvular Heart Disease, Imaging, Nuclear Cardiology and PET Ventricular Structure and Function Source Type: research

Short-Term Outcome and Hemodynamic Performance of Next-Generation Self-Expanding Versus Balloon-Expandable Transcatheter Aortic Valves in Patients With Small Aortic Annulus: A Multicenter Propensity-Matched Comparison Structural Heart Disease
Conclusions— Albeit a similar safety profile with low clinical event rates, transcatheter aortic valve replacement with the ACURATE neo valve resulted in lower transvalvular gradients and consequently less prosthesis–patient mismatch compared with the SAPIEN 3 in patients with small annulus. These results emphasize the need of careful prosthesis selection in each individual patient.
Source: Circulation: Cardiovascular Interventions - September 26, 2017 Category: Cardiology Authors: Mauri, V., Kim, W. K., Abumayyaleh, M., Walther, T., Moellmann, H., Schaefer, U., Conradi, L., Hengstenberg, C., Hilker, M., Wahlers, T., Baldus, S., Rudolph, V., Madershahian, N., Rudolph, T. K. Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation Structural Heart Disease Source Type: research

Low-Flow Severe Aortic Stenosis: Evolving Role of Transcatheter Aortic Valve Replacement Advances in Interventional Cardiology
The definition of severe aortic stenosis has classically and retrospectively been based on the natural history of patients with medically managed aortic stenosis and preserved left ventricular function in an era where surgical aortic valve replacement was the sole therapy. We now recognize that this disease is more heterogeneous and includes important subsets of patients with low stroke volume index (low flow) and low-gradient with reduced (classical) or preserved (paradoxical) ejection fraction. These patients pose diagnostic and treatment dilemmas, requiring a comprehensive assessment with integration of multimodality im...
Source: Circulation: Cardiovascular Interventions - August 9, 2017 Category: Cardiology Authors: Saybolt, M. D., Fiorilli, P. N., Gertz, Z. M., Herrmann, H. C. Tags: Valvular Heart Disease, Catheter-Based Coronary and Valvular Interventions Advances in Interventional Cardiology Source Type: research

Optimized Screening of Coronary Artery Disease With Invasive Coronary Angiography and Ad Hoc Percutaneous Coronary Intervention During Transcatheter Aortic Valve Replacement Structural Heart Disease
Conclusions— In patients undergoing TAVR, screening of CAD with invasive coronary angiography and ad hoc PCI during TAVR is feasible and was not associated with increased periprocedural risks. PCI followed by TAVR in the same session had similar outcomes than TAVR in which PCI was not performed.
Source: Circulation: Cardiovascular Interventions - August 2, 2017 Category: Cardiology Authors: Barbanti, M., Todaro, D., Costa, G., Pilato, G., Picci, A., Gulino, S., Capranzano, P., La Spina, K., Di Simone, E., DArrigo, P., Deste, W., Indelicato, A., Cannata, S., Giannazzo, D., Imme, S., Tamburino, C., Patane, M., Buccheri, S., Capodanno, D., Sgro Tags: Diagnostic Testing, Aortic Valve Replacement/Transcatheter Aortic Valve Implantation Structural Heart Disease Source Type: research

Late Results of Cox Maze III Procedure in Patients with Atrial Fibrillation Associated with Structural Heart Disease
Conclusions: The Cox-Maze III procedure, in our experience, is efficacious for sinus rhythm mainte nance, with very low late mortality and stroke rates.Resumo Fundamento: A opera ção de Cox-Maze III é uma das variantes técnicas no tratamento cirúrgico da fibrilação atrial (FA). Objetivos: Estudar os resultados tardios da operação de Cox-Maze III, quanto à eficácia na manutenção de ritmo sinusal e taxas de mortalidade e acidente vascular cerebral (AVC). Método s: Entre janeiro de 2006 a janeiro de 2013, 93 pacientes foram submetidos a operação de Cox-Maze III por corte e sutura associada a correção de card...
Source: Arquivos Brasileiros de Cardiologia - July 31, 2017 Category: Cardiology Source Type: research

Impact of Forward Stroke Volume Response on Clinical and Structural Outcomes After Percutaneous Mitral Valve Repair With MitraClip Structural Heart Disease
Conclusions— FSV increase after MitraClip implantation was associated with more favorable clinical and anatomic outcomes. Severity and pathogenesis of mitral regurgitation and pre-MitraClip FSV predicted postprocedural FSV response.
Source: Circulation: Cardiovascular Interventions - July 11, 2017 Category: Cardiology Authors: Kubo, S., Nakamura, M., Shiota, T., Itabashi, Y., Mizutani, Y., Nakajima, Y., Meemook, K., Hussaini, A., Makar, M., Siegel, R. J., Kar, S. Tags: Catheter-Based Coronary and Valvular Interventions Structural Heart Disease Source Type: research

Clinical and Echocardiographic Outcomes Following Permanent Pacemaker Implantation After Transcatheter Aortic Valve Replacement: Meta-Analysis and Meta-Regression Structural Heart Disease
Conclusions— PPM implantation is not associated with increased risk of all-cause mortality, cardiovascular mortality, stroke, or myocardial infarction both at short- and long-term follow-up. However, PPM is associated with impaired left ventricular ejection fraction recovery post-transcatheter aortic valve replacement.
Source: Circulation: Cardiovascular Interventions - July 11, 2017 Category: Cardiology Authors: Mohananey, D., Jobanputra, Y., Kumar, A., Krishnaswamy, A., Mick, S., White, J. M., Kapadia, S. R. Tags: Arrhythmias, Valvular Heart Disease, Catheter-Based Coronary and Valvular Interventions, Pacemaker Structural Heart Disease Source Type: research

Outcome With the Repositionable and Retrievable Boston Scientific Lotus Valve Compared With the Balloon-Expandable Edwards Sapien 3 Valve in Patients Undergoing Transfemoral Aortic Valve Replacement Structural Heart Disease
Conclusions— Transfemoral aortic valve replacement with the ES3 and the Lotus were associated with similar 30-day, 12-month, and 24-month clinical outcomes. Need for permanent pacemaker implantation was significantly higher with the repositionable Lotus device. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT02162069.
Source: Circulation: Cardiovascular Interventions - May 31, 2017 Category: Cardiology Authors: Seeger, J., Gonska, B., Rottbauer, W., Wohrle, J. Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation Structural Heart Disease Source Type: research

Morbidity and Mortality Associated With Balloon Aortic Valvuloplasty: A National Perspective Structural Heart Disease
Conclusions— In a contemporary national registry, BAV is associated with significant morbidity and mortality that are similar to TAVR. With the substantial increase in BAV utilization and the continuous improvement in TAVR outcomes, these data have important implications to aid clinicians in the selection of appropriate BAV candidates.
Source: Circulation: Cardiovascular Interventions - May 11, 2017 Category: Cardiology Authors: Alkhouli, M., Zack, C. J., Sarraf, M., Bashir, R., Nishimura, R. A., Eleid, M. F., Nkomo, V. T., Sandhu, G. S., Gulati, R., Greason, K. L., Holmes, D. R., Rihal, C. S. Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation, Catheter-Based Coronary and Valvular Interventions Structural Heart Disease Source Type: research

Long-Term Outcomes of Patients With Mediastinal Radiation-Associated Severe Aortic Stenosis and Subsequent Surgical Aortic Valve Replacement: A Matched Cohort Study Valvular Heart Disease
BackgroundCardiac disease after mediastinal radiotherapy for thoracic malignancy (chest radiotherapy [XRT]) often manifests as progressive aortic stenosis. In patients with XRT‐induced severe aortic stenosis undergoing surgical aortic valve replacement (SAVR), we sought to: (1) study long‐term survival and compare these patients with a matched cohort undergoing SAVR during the same time frame; and (2) identify potential predictors of long‐term mortality.Methods and ResultsWe studied patients with symptomatic severe aortic stenosis undergoing SAVR at our institution, of which there were 172 mediastinal XRT patients (6...
Source: JAHA:Journal of the American Heart Association - May 5, 2017 Category: Cardiology Authors: Donnellan, E., Masri, A., Johnston, D. R., Pettersson, G. B., Rodriguez, L. L., Popovic, Z. B., Roselli, E. E., Smedira, N. G., Svensson, L. G., Griffin, B. P., Desai, M. Y. Tags: Valvular Heart Disease Original Research Source Type: research

Low ‐flow/low‐gradient aortic stenosis—Still a diagnostic and therapeutic challenge
Aortic stenosis (AS) is the most frequently observed valvular heart disease. During the symptomatic stage, the rate of death increases dramatically, so that a precise diagnostic approach is taken to guide therapeutic options. Of patients with severe AS, 30% to 50% present with low‐flow/low‐gradient AS (LF/LGAS) status. This review focuses on LF/LGAS and the best diagnostic and therapeutic management in either classic LF/LGAS with reduced left ventricular ejection fraction (LVEF) or paradoxical LF/LGAS with preserved LVEF. Current literature demonstrates that in classic LF/LGAS it is crucial to rule out a pseudo‐sever...
Source: Clinical Cardiology - May 1, 2017 Category: Cardiology Authors: Anja Vogelgesang, Gerd Hasenfuss, Claudius Jacobshagen Tags: Review Source Type: research

Cor Triatriatum and Stroke: A Case Report and Review of Literature (P3.294)
Conclusions:This is the largest review of CTS cases with associated stroke. The review showed neuroimaging results consistent with a cardioembolic mechanism. All but two of the cases made use of anticoagulation. Three cases underwent surgery. This case has the longest follow-up and the first to demonstrate failure of anti-platelet therapy and anticoagulation. The need for further investigations regarding optimal stroke prevention in this subset of patients is emphasized.Disclosure: Dr. Diestro has nothing to disclose. Dr. Espiritu has nothing to disclose. Dr. Dorotan has nothing to disclose. Dr. Regalado has nothing to dis...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Diestro, J. D., Espiritu, A., Dorotan, M. K., Regalado, J., Pascual, J. L. Tags: Cerebrovascular Disease Case Reports II Source Type: research

Matched Comparison of Self-Expanding Transcatheter Heart Valves for the Treatment of Failed Aortic Surgical Bioprosthesis: Insights From the Valve-in-Valve International Data Registry (VIVID) Structural Heart Disease
Conclusions— In this first matched comparison of THVs for valve-in-valve implantations, Portico and CoreValve demonstrated differences in postprocedural hemodynamics and long-term clinical outcomes. Although this could be related to THV design characteristics, the impact of other procedural factors cannot be excluded and require further evaluation.
Source: Circulation: Cardiovascular Interventions - April 11, 2017 Category: Cardiology Authors: Alnasser, S., Cheema, A. N., Simonato, M., Barbanti, M., Edwards, J., Kornowski, R., Horlick, E., Wijeysundera, H. C., Testa, L., Bedogni, F., Amrane, H., Walther, T., Pelletier, M., Latib, A., Laborde, J.-C., Hildick-Smith, D., Kim, W.-K., Tchetche, D., Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation Structural Heart Disease Source Type: research

Early Results of Surgical Simultaneous Therapy for Significant Carotid Artery Stenosis and Heart Disease
Conclusion Simultaneous coronary bypass grafting as a single procedure or in combination with valve replacement and endarterectomy of severe carotid lesions with or without patients' history of previous stroke can be performed with a calculated low surgical risk. The complication rate for neurologic and myocardial events is low compared with the hazard of a single surgical repair. The in-hospital mortality is not significantly different to isolated procedures. The concomitant appearance of coronary stenosis and carotid artery disease is reasonable due to the nature of arteriosclerosis. In our opinion these patients benef...
Source: The Thoracic and Cardiovascular Surgeon - April 5, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Irqsusi, Marc Vannucchi, Alessandro Beckers, Julius Kasseckert, Stefan Waldhans, Stefan Vogt, Sebastian Moosdorf, Rainer G. H. Tags: Original Cardiovascular Source Type: research