Metoprolol Reduces Hemodynamic and Metabolic Overload in Asymptomatic Aortic Valve Stenosis Patients: A Randomized Trial [Ventricular Structure and Function]

Conclusions— In patients with asymptomatic AS, metoprolol increases systolic ejection time and reduces aortic valve gradients, global afterload, and myocardial oxygen requirements. Thus, metoprolol displays favorable hemodynamic and metabolic effects and could improve outcome in patients with asymptomatic AS. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT02076711.
Source: Circulation: Cardiovascular Imaging - Category: Radiology Authors: Tags: Clinical Studies, Metabolism, Valvular Heart Disease, Imaging, Nuclear Cardiology and PET Ventricular Structure and Function Source Type: research