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Condition: Brain Tumor

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Total 780 results found since Jan 2013.

Optimizing maximum resection of glioblastoma: Raman spectroscopy versus 5-aminolevulinic acid
CONCLUSIONS: According to the study data, RS is capable of detecting tumor-infiltrated brain with higher sensitivity but lower specificity than the current standard of 5-ALA. With further technological and workflow advancements, RS in combination with protoporphyrin IX fluorescence may contribute to pathology-tailored glioma resection in the future.PMID:36681953 | DOI:10.3171/2022.11.JNS22693
Source: Journal of Neurosurgery - January 22, 2023 Category: Neurosurgery Authors: Johannes Herta Anna Cho Thomas Roetzer-Pejrimovsky Romana H öftberger Wolfgang Marik Gernot Kronreif Tanja Peilnsteiner Karl R össler Stefan Wolfsberger Source Type: research

Feasibility and acceptability of the Resilient Living program among persons with stroke or brain tumor and their family caregivers
CONCLUSION: The study confirms prior research suggesting that interventions targeting resilience are feasible, but larger studies with more rigorous methods are needed to appreciate the influence of resilience interventions in persons with brain disorders and their caregivers. Further research is needed to identify the characteristics of those most likely to benefit from resilience interventions and the optimal timing of such interventions.PMID:36617758 | DOI:10.3233/NRE-220127
Source: NeuroRehabilitation - January 9, 2023 Category: Rehabilitation Authors: Lori M Rhudy Emily A Hines Ellen M Farr Sherry S Chesak Source Type: research

Implementation of Automated Pipeline for Resting-State fMRI Analysis with PACS Integration
AbstractIn recent years, the quantity and complexity of medical imaging acquisition and processing have increased tremendously. The explosion in volume and need for advanced imaging analysis have led to the creation of numerous software programs, which have begun to be incorporated into clinical practice for indications such as automated stroke assessment, brain tumor perfusion processing, and hippocampal volume analysis. Despite these advances, there remains a need for specialized, custom-built software for advanced algorithms and new areas of research that is not widely available or adequately integrated in these “out-...
Source: Journal of Digital Imaging - January 3, 2023 Category: Radiology Source Type: research

Systematic analysis of brain and skull ischemic injury expression profiles reveals associations of the tumor immune microenvironment and cell death with ischemic stroke
ConclusionThis systematic analysis not only helps in the understanding of the changes in the gene expression profiles of both the brain and skull with ischemic injury but also reveals the association of the tumor immune microenvironment and cell death with ischemic stroke.
Source: Frontiers in Immunology - December 20, 2022 Category: Allergy & Immunology Source Type: research

Neuro faces of beneficial T cells: essential in brain, impaired in aging and neurological diseases, and activated functionally by neurotransmitters and neuropeptides
Neural Regen Res. 2023 Jun;18(6):1165-1178. doi: 10.4103/1673-5374.357903.ABSTRACTT cells are essential for a healthy life, performing continuously: immune surveillance, recognition, protection, activation, suppression, assistance, eradication, secretion, adhesion, migration, homing, communications, and additional tasks. This paper describes five aspects of normal beneficial T cells in the healthy or diseased brain. First, normal beneficial T cells are essential for normal healthy brain functions: cognition, spatial learning, memory, adult neurogenesis, and neuroprotection. T cells decrease secondary neuronal degeneration,...
Source: Cell Research - December 1, 2022 Category: Cytology Authors: Mia Levite Source Type: research

Effect of gait distance during robot training on walking independence after acute brain injury
This study aimed to determine whether the distance of gait training using a hybrid assistive limb (HAL) is related to the improvement of walking independence in patients with acute brain injury. This was an exploratory, observational study. Thirty patients having hemiplegia (functional ambulation category, FAC score ≤ 2) with acute stroke or after brain tumor surgery were included. Patients performed 4 sessions of gait training using HAL (60 min/session), 1-3 sessions/week, combined with conventional physical therapy. The gait distance achieved in the four training sessions using HAL was measured. FAC score was measured ...
Source: Assistive Technology - November 28, 2022 Category: Rehabilitation Authors: Gakuto Kitamura Manabu Nankaku Takayuki Kikuchi Hidehisa Nishi Hiroki Tanaka Toru Nishikawa Honami Yonezawa Taishi Kajimoto Takumi Kawano Ayumi Ohtagaki Eriko Mashimoto Susumu Miyamoto Ryosuke Ikeguchi Shuichi Matsuda Source Type: research

From kitchen to clinic: Pharmacotherapeutic potential of common spices in Indian cooking in age-related neurological disorders
Aging is described as an advanced time-related collection of changes that may negatively affect with the risk of several diseases or death. Aging is a main factor of several age-related neurological disorders, including neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease, and dementia), stroke, neuroinflammation, neurotoxicity, brain tumors, oxidative stress, and reactive oxygen species (ROS). Currently available medications for age-related neurological disorders may lead to several side effects, such as headache, diarrhea, nausea, gastrointestinal (GI) diseases, dyskinesia, and hallucinosis. These day...
Source: Frontiers in Pharmacology - November 10, 2022 Category: Drugs & Pharmacology Source Type: research

Transgenic animal models to explore and modulate the blood brain and blood retinal barriers of the CNS
AbstractThe unique environment of the brain and retina is tightly regulated by blood –brain barrier and the blood-retinal barrier, respectively, to ensure proper neuronal function. Endothelial cells within these tissues possess distinct properties that allow for controlled passage of solutes and fluids. Pericytes, glia cells and neurons signal to endothelial cells (ECs) to form an d maintain the barriers and control blood flow, helping to create the neurovascular unit. This barrier is lost in a wide range of diseases affecting the central nervous system (CNS) and retina such as brain tumors, stroke, dementia, and in the ...
Source: Fluids and Barriers of the CNS - November 1, 2022 Category: Neuroscience Source Type: research

A Chinese female patient with LGI1 and mGluR5 antibodies: A case report
We present a case of AE with dual seropositive antibodies of LGI1 and mGluR5 in a 65-year-old woman who presented with sudden onset left faciobrachial dystonic seizures and unresponsive for 5 hours. Diagnosis: The patient was diagnosed with anti-LGI1 AE and anti-mGluR5 AE mainly based on the clinical symptoms and further test of the antibody in serum and cerebral spinal fluid (CSF). Interventions and outcomes: The patient was treated with glucocorticoid intravenous drip. We also gave her the therapy of immunoglobulin (25 g q.d) for 5 days and anti-epileptic therapy. She had no more convulsions on the left s...
Source: Medicine - October 28, 2022 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Exploratory study to assess feasibility of intracerebral hemorrhage detection by point of care cranial ultrasound
ConclusionsOur exploratory analysis yielded preliminary data on use of point of care cranial ultrasound for ICH diagnosis to inform imaging techniques, cranial topography on B mode and sample size estimation for future studies to evaluate sensitivity and specificity of cranial POCUS in adult patients. This pilot study is limited by small sample size and over representation of ICH in the study. Cranial POCUS is feasible using POCUS machines and may have potential as a screening tool if validated in adequately powered studies.
Source: Critical Ultrasound Journal - October 17, 2022 Category: Radiology Source Type: research

Applicability and efficacy of ultrasound elastography in neurosurgery: a systematic review of the literature
CONCLUSIONS: This systematic review showed that, despite the lack of strong evidences, USE is a valid intraoperative tool, especially in oncological neurosurgery.PMID:36239425 | DOI:10.23736/S0390-5616.22.05866-0
Source: Journal of Neurosurgical Sciences - October 14, 2022 Category: Neurosurgery Authors: Ismail Zaed Giuseppe M Della Pepa Delia Cannizzaro Grazia Menna Andrea Cardia Source Type: research