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Condition: Anxiety

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Total 3617 results found since Jan 2013.

Direct and indirect impact of SARS-CoV-2 on the brain
AbstractAlthough COVID-19 is mostly a pulmonary disease, it is now well accepted that it can cause a much broader spectrum of signs and symptoms and affect many other organs and tissue. From mild anosmia to severe ischemic stroke, the impact of SARS-CoV-2 on the central nervous system is still a great challenge to scientists and health care practitioners. Besides the acute and severe neurological problems described, as encephalopathies, leptomeningitis, and stroke, after 2  years of pandemic, the chronic impact observed during long-COVID or the post-acute sequelae of COVID-19 (PASC) greatly intrigues scientists worldwide....
Source: Human Genetics - April 1, 2023 Category: Genetics & Stem Cells Source Type: research

America Has No Way to Take Care of Mentally Ill People
With evermore unhoused people on the streets of our biggest cities, and publicized subway crimes in New York, mental health treatment is again in the news. Politicians speak about “caring” for the mentally ill in a new way, which turns out to be the old way—putting them away. The mention of involuntary confinement, predictably, sparks anxiety and controversy, giving rise to the question of whom this policy is meant to help: the people taken away or the rest of population, those shopping, jogging, carrying groceries home, who, presumably, will no longer be bothered by the inconvenient reality of a person s...
Source: TIME: Health - March 31, 2023 Category: Consumer Health News Authors: Mona Simpson Tags: Uncategorized freelance Psychology Source Type: news

Supervised, Self-Administered Tablet-Based Cognitive Assessment in Neurodegenerative Disorders and Stroke
CONCLUSIONS: This tablet-based application was found to be widely acceptable to participants. This study supports the validity of these tablet-based assessments in the differentiation of healthy controls from patients with neurocognitive deficits in a variety of cognitive domains and across multiple neurological disease etiologies.PMID:36996783 | DOI:10.1159/000527060
Source: Dementia and Geriatric Cognitive Disorders - March 30, 2023 Category: Psychiatry Authors: Kelly L Sloane Rachel Fabian Amy Wright Sadhvi Saxena Kevin Kim Colin M Stein Zafer Keser Shenly Glenn Argye E Hillis Source Type: research

Esketamine ameliorates post-stroke anxiety by modulating microglial HDAC3/NF- κB/COX1 inflammatory signaling in ischemic cortex
In conclusion, this study suggests esketamine could alleviate microglial activation, reduces inflammatory cytokine, and inhibits the expression of HDAC3 and NF-κB in the cortex of PSA mice to attenuate anxiety-like behavior. Our results provided a new potential therapeutic target for applying esketamine to PSA.PMID:36997050 | DOI:10.1016/j.ejphar.2023.175667
Source: European Journal of Pharmacology - March 30, 2023 Category: Drugs & Pharmacology Authors: Ailin Huang Yang Chen Shaoshuang Wang Hailiang Du Ao Guan Huanghui Wu Qian Zhai Na Duan Xuying Li Pin Zhao Yulin Zhu Juan Bai Ye Xiao Tingting Yang Qiang Wang Bin Deng Source Type: research

Supervised, Self-Administered Tablet-Based Cognitive Assessment in Neurodegenerative Disorders and Stroke
CONCLUSIONS: This tablet-based application was found to be widely acceptable to participants. This study supports the validity of these tablet-based assessments in the differentiation of healthy controls from patients with neurocognitive deficits in a variety of cognitive domains and across multiple neurological disease etiologies.PMID:36996783 | DOI:10.1159/000527060
Source: Dementia and Geriatric Cognitive Disorders - March 30, 2023 Category: Psychiatry Authors: Kelly L Sloane Rachel Fabian Amy Wright Sadhvi Saxena Kevin Kim Colin M Stein Zafer Keser Shenly Glenn Argye E Hillis Source Type: research

Esketamine ameliorates post-stroke anxiety by modulating microglial HDAC3/NF- κB/COX1 inflammatory signaling in ischemic cortex
In conclusion, this study suggests esketamine could alleviate microglial activation, reduces inflammatory cytokine, and inhibits the expression of HDAC3 and NF-κB in the cortex of PSA mice to attenuate anxiety-like behavior. Our results provided a new potential therapeutic target for applying esketamine to PSA.PMID:36997050 | DOI:10.1016/j.ejphar.2023.175667
Source: European Journal of Pharmacology - March 30, 2023 Category: Drugs & Pharmacology Authors: Ailin Huang Yang Chen Shaoshuang Wang Hailiang Du Ao Guan Huanghui Wu Qian Zhai Na Duan Xuying Li Pin Zhao Yulin Zhu Juan Bai Ye Xiao Tingting Yang Qiang Wang Bin Deng Source Type: research

Supervised, Self-Administered Tablet-Based Cognitive Assessment in Neurodegenerative Disorders and Stroke
Conclusions: This tablet-based application was found to be widely acceptable to participants. This study supports the validity of these tablet-based assessments in the differentiation of healthy controls from patients with neurocognitive deficits in a variety of cognitive domains and across multiple neurological disease etiologies.Dement Geriatr Cogn Disord
Source: Dementia and Geriatric Cognitive Disorders - March 30, 2023 Category: Geriatrics Source Type: research

IJERPH, Vol. 20, Pages 5328: Biological, Psychiatric, Psychosocial, and Cognitive Factors of Poststroke Depression
Discussion: Results suggest that PSD is likely multifactorial and extends the literature by demonstrating that a comorbid anxiety disorder correlated strongest with PSD. Poststroke screening and treatment plans should address not only depression but comorbid anxiety.
Source: International Journal of Environmental Research and Public Health - March 30, 2023 Category: Environmental Health Authors: Mario F. Dulay Amber Criswell Timea M. Hodics Tags: Article Source Type: research

Stellate ganglion block ameliorated central post-stroke pain with comorbid anxiety and depression through inhibiting HIF-1 α/NLRP3 signaling following thalamic hemorrhagic stroke
Central post-stroke pain (CPSP) is an intractable and disabling central neuropathic pain that severely affects patients ’ lives, well-being, and socialization abilities. However, CPSP has been poorly studied me...
Source: Journal of Neuroinflammation - March 21, 2023 Category: Neurology Authors: Zhong-Mou Shi, Jun-Jie Jing, Zheng-Jie Xue, Wen-Jun Chen, Yan-Bin Tang, Du-Juan Chen, Xin-Yi Qi, Li Huang, Yi-Qing Zou, Xiao-Zhi Wu and Fei Yang Tags: Research Source Type: research

Acori Tatarinowii Rhizoma: A comprehensive review of its chemical composition, pharmacology, pharmacokinetics and toxicity
Acori Tatarinowii Rhizoma (ATR, Shi Chang Pu in Chinese), a natural product with multiple targets in various diseases. This review provides the comprehensive summary of the chemical composition, pharmacological effects, pharmacokinetics parameters and toxicity of ATR. The results indicated that ATR possesses a wide spectrum of chemical composition, including volatile oil, terpenoids, organic acids, flavonoids, amino acids, lignin, carbohydrates and so on. Accumulating evidence from various studies has shown that ATR exerts a wide range of pharmacological properties, including protecting nerve cells, alleviating learning an...
Source: Frontiers in Pharmacology - March 16, 2023 Category: Drugs & Pharmacology Source Type: research

Activation of CREB-BDNF Pathway in Pyramidal Neurons in the Hippocampus Improves the Neurological Outcome of Mice with Ischemic Stroke
In this study, overexpression of CREB protein in pyramidal neurons in vCA1 by AAV virus significantly upregulated the content of BDNF and ameliorated the dysfunction induced by ischemic stroke. Our results demonstrated activation of the CREB-BDNF pathway in vCA1 pyramidal neurons significantly improved neurological deficits, pain perception, anxiety, and depression induced by ischemic stroke.
Source: Molecular Neurobiology - March 3, 2023 Category: Neurology Source Type: research

A Sugar Replacement May Be Linked to Heart Attacks and Strokes. Don ’ t Throw Out Your Stash Yet
Sugar replacements are everywhere in foods and beverages. But despite their ubiquity, the scientific verdict on whether or not they pose health risks ping pongs back and forth. Every so often, though, a study is published with a conclusion so shocking that it forces people to reassess their pantries. A Feb. 27 study published in the journal Nature Medicine now seems to have dealt such a blow to the sweetener erythritol, with data that suggest a connection between the ingredient and cardiovascular events such as clotting, stroke, and heart attacks. [time-brightcove not-tgx=”true”] But before you clear your shel...
Source: TIME: Health - March 3, 2023 Category: Consumer Health News Authors: Haley Weiss Tags: Uncategorized Diet & Nutrition healthscienceclimate Source Type: news

Your Houseplants Have Some Powerful Health Benefits
Every morning, I spring out of bed, eager to check on my housemates: Alvin the monstera albo, Allison the other albo, Dominic the philodendron domesticum variegated, and Connie the Thai constellation monstera. Yes, my vegetal friends all have names—which you understand if you’re a plant person, too. Collecting and caring for houseplants boomed in popularity during the pandemic, especially among younger adults who often don’t have abundant outdoor space. Americans spent $8.5 billion more on gardening-related items in 2020 than in 2019, according to the U.S. Census Bureau. Vibrant communities blossomed on s...
Source: TIME: Health - March 2, 2023 Category: Consumer Health News Authors: Angela Haupt Tags: Uncategorized healthscienceclimate Research Wellbeing Source Type: news

Psychometric properties of Indonesian version of sleep condition indicator for screening poststroke insomnia
CONCLUSION: The study results revealed that the 8-item ISCI is a reliable and valid screening tool for detecting insomnia symptoms according to the DSM-5 criteria in the chronic period after stroke.PMID:36854859 | DOI:10.1007/s11325-023-02797-1
Source: Sleep and Breathing - March 1, 2023 Category: Sleep Medicine Authors: Faizul Hasan Amelia Nur Vidyanti Pei-Shan Tsai Dean Wu Hsin-Chien Lee Lia Taurussia Yuliana Debby Syahru Romadlon Ollyvia Freeska Dwi Marta Hsiao-Yean Chiu Source Type: research