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Specialty: Surgery
Condition: Bleeding

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Total 190 results found since Jan 2013.

Protamine Reduces Bleeding Complications without Increasing the Risk of Stroke after Carotid Endarterectomy: A Meta-analysis
The aim was to evaluate the safety and efficacy of heparin reversal with protamine after completion of carotid endarterectomy (CEA), summarising the available data from both randomised and non-randomised studies.
Source: European Journal of Vascular and Endovascular Surgery - July 3, 2016 Category: Surgery Authors: J.D. Kakisis, C.N. Antonopoulos, K.G. Moulakakis, F. Schneider, G. Geroulakos, J.B. Ricco Tags: Review Source Type: research

Bleeding, Transfusion and the Risk of Stroke after Coronary Surgery: A Prospective Cohort Study of 2,357 patients
This study was planned to investigate the impact of severe bleeding and blood transfusion on the development of stroke after coronary surgery.
Source: International Journal of Surgery - June 21, 2016 Category: Surgery Authors: Fausto Biancari, Tuomas Tauriainen, Andrea Perrotti, Magnus Dalén, Giuseppe Faggian, Ilaria Franzese, Sidney Chocron, Vito G. Ruggieri, Karl Bounader, Helmut Gulbins, Daniel Reichart, Peter Svenarud, Giuseppe Santarpino, Theodor Fischlein, Tamas Puski, D Tags: Original Research Source Type: research

Use of Protamine for Anticoagulation During Carotid Endarterectomy: A Meta-Analysis
Use of protamine following carotid endarterectomy (CEA) is associated with a reduction in bleeding complications without increasing major thrombotic outcomes of stroke, myocardial infarction or death.
Source: Journal of Vascular Surgery - May 23, 2016 Category: Surgery Authors: K.A. Newhall, E.C. Saunders, R.J. Larson Tags: Abstract Source Type: research

Efficacy and Safety of Transbrachial Access for Iliac Endovascular Interventions
Conclusion: Brachial artery access enables endovascular treatment of iliac artery disease in the majority of patients, although an adjunctive transfemoral access may be required. However, the high incidences of access site complications and cerebral events remain a significant limitation of the transbrachial approach.
Source: Journal of Endovascular Therapy - May 10, 2016 Category: Surgery Authors: Stavroulakis, K., Usai, M. V., Torsello, G., Schwindt, A., Stachmann, A., Beropoulis, E., Bisdas, T. Tags: Lower Limb Interventions Source Type: research

Invited commentary
The key findings were that adding clopidogrel to regular aspirin therapy ≤48 hours of carotid endarterectomy (CEA) was associated with significant reductions in postoperative stroke, at the expense of increased bleeding complications.1 The latter will, inevitably, reinforce certain prejudices regarding dual-antiplatelet therapy (DAPT), even though the rate of bleeding complications was only 1.2% (DAPT) vs 0.7% (monotherapy). However, before uncritically disregarding any role for DAPT, it is worth considering why this debate is so important.
Source: Journal of Vascular Surgery - April 21, 2016 Category: Surgery Authors: A. Ross Naylor Tags: Clinical research study Source Type: research

Long-term Outcome After EndoVAC Hybrid Repair of Infected Vascular Reconstructions.
CONCLUSION: The EndoVAC technique is an alternative, less invasive, option for treatment of infected vascular reconstructions in selected cases, when neither traditional radical surgery, nor conservative simple negative pressure wound therapy are considered feasible or safe. The exact indications for this alternative hybrid treatment need to be established. PMID: 26944600 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - March 1, 2016 Category: Surgery Authors: Thorbjørnsen K, Djavani Gidlund K, Björck M, Kragsterman B, Wanhainen A Tags: Eur J Vasc Endovasc Surg Source Type: research

Results of Carotid Endarterectomy Using Bovine Pericardium Patch Closure, with a Review of Pertinent Literature.
This study reviews a large carotid surgery series using this patch. Data were gathered on 464 consecutive carotid operations using the bovine pericardium patch; all complications were analyzed and pertinent literature review was performed. Of 464 procedures, 218 (47%) were performed for symptomatic disease. Total perioperative ipsilateral stroke rate was 0.65 per cent. A low rate of postoperative bleeding was noted. Recurrence of >70 per cent stenosis was 1.6 per cent at follow-up of 26 months in 410 patients. Handling was subjectively described as excellent. Literature review comprising 3239 carotid operations revealed...
Source: The American Surgeon - February 29, 2016 Category: Surgery Authors: Olsen SB, Mcquinn WC, Feliciano P Tags: Am Surg Source Type: research

Dual antiplatelet therapy reduces stroke but increases bleeding at the time of carotid endarterectomy
This study examined the effect of preoperative dual antiplatelet therapy (aspirin and clopidogrel) on in-hospital CEA outcomes.
Source: Journal of Vascular Surgery - February 28, 2016 Category: Surgery Authors: Douglas W. Jones, Philip P. Goodney, Mark F. Conrad, Brian W. Nolan, Eva M. Rzucidlo, Richard J. Powell, Jack L. Cronenwett, David H. Stone Tags: Clinical paper Source Type: research

Urgent Aggressive Best Medical Therapy Prior to Carotid Surgery Dramatically Reduces Recurrent Stroke Prior to Surgery Without Significantly Increasing Peri-operative Bleeding Complications
Abstract
Source: European Journal of Vascular and Endovascular Surgery - February 25, 2016 Category: Surgery Authors: R.K. Ramachandran, A. Owen-Falkenberg, B. Gottschalksen, K. Ellemann, S. Shahidi Source Type: research

Pancreatogastrostomy Versus Pancreatojejunostomy for RECOnstruction After PANCreatoduodenectomy (RECOPANC, DRKS 00000767): Perioperative and Long-term Results of a Multicenter Randomized Controlled Trial
Conclusions: The rate of grade B/C fistula after PG versus PJ was not different. There were more postoperative bleeding events with PG. Perioperative morbidity and mortality of pancreatoduodenectomy seem to be underestimated, even in the high-volume center setting.
Source: Annals of Surgery - February 8, 2016 Category: Surgery Tags: Randomized Controlled Trials Source Type: research

Meta-Analysis of Studies Evaluating the Effect of Cilostazol on Major Outcomes After Carotid Stenting
Conclusion: Cilostazol seems to decrease total ISR rates in patients undergoing CAS without affecting MI/stroke/death events, both in the early and late settings.
Source: Journal of Endovascular Therapy - January 12, 2016 Category: Surgery Authors: Galyfos, G., Geropapas, G., Sigala, F., Aggeli, K., Sianou, A., Filis, K. Tags: Carotid Artery Stenting Source Type: research

Heparins – DOACS – VKA
Patients with cancer are at increased risk of venous thromboembolism (VTE). At the same time they have often an underlying bleeding risk. That can often make decisions surrounding the administration of anticoagulants complicate. Individual risk-benefit calculation is necessary. During hospital stage the patients get, if there are no contraindications, a medical VTE prophylaxis with low molecular weight heparin (LMWH). Whereas outpatients don`t get a prophylaxis because they are at low risk of thromboembolism. If additional risk factor for VTE exists a decision for medical VTE prophylaxis should be taken into account. In pa...
Source: Phlebologie - December 2, 2015 Category: Surgery Source Type: research

A new device for the prevention of pulmonary embolism in critically ill patients: Results of the European Angel Catheter Registry
CONCLUSION: Early bedside placement of an IVC filter–catheter is possible, and our results suggest that this is a safe, effective alternative to short-term PE prophylaxis for high-risk patients with contraindications to anticoagulation. LEVEL OF EVIDENCE: Therapeutic study, level V.
Source: Journal of Trauma and Acute Care Surgery - September 1, 2015 Category: Surgery Tags: Original Articles Source Type: research

Propensity-matched analysis of minimally invasive mitral valve repair using a nationwide surgical database
Conclusions MICS-mitral via RT was successful without compromising the clinical outcomes. Although the operation time and postoperative bleeding should be improved, an RT approach is safe in appropriately selected patients, especially those <60 years of age or treated in a high-volume center.
Source: Surgery Today - August 15, 2015 Category: Surgery Source Type: research

Dual Antiplatelet Therapy Prior to Expedited Carotid Surgery Reduces Recurrent Events Prior to Surgery without Significantly Increasing Peri-operative Bleeding Complications.
CONCLUSION: Early introduction of dual antiplatelet therapy was associated with a significant reduction in recurrent neurological events and spontaneous embolization prior to CEA, without incurring a significant increase in major peri-operative bleeding complications. PMID: 26283034 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - August 14, 2015 Category: Surgery Authors: Batchelder A, Hunter J, Cairns V, Sandford R, Munshi A, Naylor AR Tags: Eur J Vasc Endovasc Surg Source Type: research