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Specialty: Surgery
Condition: Bleeding
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Total 190 results found since Jan 2013.
Minimal access compared to sternotomy for aortic root and arch surgery
CONCLUSION: The partial upper sternotomy approach is safe and feasible for aortic root and arch surgery with morbidity and mortality rates similar to full sternotomy, with the advantages of less blood loss and transfusions need, faster extubation, and shorter length of hospital stay.PMID:35255771 | DOI:10.1080/00015458.2022.2050979
Source: Acta Chirurgica Belgica - March 8, 2022 Category: Surgery Authors: Anastasia Boudart Alaaddin Yilmaz Abdullah Kaya Source Type: research
Peri-Operative Outcomes of Carotid Endarterectomy are Not Improved on Dual Antiplatelet Therapy vs. Aspirin Monotherapy: A Systematic Review and Meta-Analysis
CONCLUSION: This meta-analysis found that CEA while on DAPT increased the risk of haemorrhagic complications, with similar rates of ischaemic complications, vs. aspirin monotherapy. This suggests that the risks of performing CEA on DAPT outweigh the benefits, even in patients with symptomatic carotid stenosis. The overall quality of studies was low, and improved reporting of CEA outcomes in the literature is necessary.PMID:35241374 | DOI:10.1016/j.ejvs.2021.12.037
Source: PubMed: Eur J Vasc Endovasc ... - March 4, 2022 Category: Surgery Authors: Jerry C Ku Shervin Taslimi Jeffrey Zuccato Christopher R Pasarikovski Nathalie Nasr Ofir Chechik Emiliano Chisci Daniele Bissacco Vincent Larrue Yefim Rabinovich Stefano Michelagnoli Piergiorgio G Settembrini Stefano M Priola Michael D Cusimano Victor X D Source Type: research
Mirror Mirror on the Wall, Which Is the Most Protective Antithrombotic Therapy of Them All?
Antiplatelet therapy remains a matter of controversy in patients undergoing carotid endarterectomy (CEA). It is still not clear whether the benefit of dual antiplatelet therapy (DAPT) in terms of peri-procedural stroke is counterbalanced by the increased risk of bleeding. To answer this question, Ku et al.1 aimed to add new information compared with a recently published meta-analysis.2,3 Overall data from 47 411 patients (30% receiving DAPT; mixed symptomatic status) reported in 11 studies (two randomised controlled trials [RCTs]) were included.
Source: European Journal of Vascular and Endovascular Surgery - March 2, 2022 Category: Surgery Authors: Barbara Rantner, Gert J. de Borst Tags: Invited Commentary Source Type: research
Protamine for Heparin Reversal After Carotid Endarterectomy is Significantly Underutilised: Results from a UK National Survey
Protamine sulphate is widely used to reverse anticoagulation with heparin after various surgical and interventional procedures, and is currently the only drug licensed for this indication. Reversal of intra-operative heparin after carotid endarterectomy (CEA) to reduce the incidence of post-operative bleeding complications, particularly re-exploration for neck haematoma (NH) with airway compromise, has received renewed attention in recent years. Two meta-analyses have shown that intra-operative heparin reversal can be done without increasing the risk of post-operative stroke, myocardial infarction (MI), or death.
Source: European Journal of Vascular and Endovascular Surgery - February 17, 2022 Category: Surgery Authors: Aminder A. Singh, Jonathan R. Boyle, Ian Chetter, Florian Falter Tags: Research Letter Source Type: research
Editorial Commentary: The Current Evidence in Support of Tranexamic Acid in Arthroscopic Surgery Is Poor
Tranexamic acid (TXA) has been used to treat severe bleeding events for nearly 60 years and is on the list of World Health Organization essential medicines. Initially, it was described to treat heavy menstrual bleeding, but it is now used for a variety of applications. In orthopedic surgery, TXA is commonly used to reduce bleeding after total joint arthroplasty and spine surgery. The use of TXA for joint arthroplasty has been principally endorsed by various orthopedic societies, but they have also criticized a lack of evidence for high-risk patients with a history of pulmonary embolus, vascular stents, stroke, transient is...
Source: Arthroscopy - Journal of Arthroscopic and Related Surgery - February 1, 2022 Category: Surgery Authors: Erik Hohmann Tags: Editorial Commentary Source Type: research
Protamine use in transcarotid arterial revascularization
CONCLUSIONS: We identified a near 1:1 ratio of a protamine/heparin dosing regimen for the reversal of heparin during TCAR, with postoperative bleeding complications similar to those reported in the literature. However, patients who received a lower protamine/heparin ratio did not experience bleeding complications. In the era of protamine shortages, a future larger-scale study is needed to evaluate the impact of a lower protamine dose on postoperative complications.PMID:35040739 | DOI:10.1177/17085381211067047
Source: Vascular - January 18, 2022 Category: Surgery Authors: John J Kanitra Rebekah L Bjorklund David J Clausen R David Hayward Renee A Paxton Jimmy C Haouilou Source Type: research
