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Specialty: Surgery
Condition: Bleeding

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Total 190 results found since Jan 2013.

Oral Surgery in Patients With Sturge-Weber Syndrome
The Sturge-Weber syndrome (SSW) is a congenital neurocutaneous malformation, with angiomas involving the leptomeningea and facial skin. This syndrome is characterized by corticocerebral angiomatosis, cerebral calcifications, ocular affections, mental retardation, increased risk of stroke, counterlateral hemiplegia, and seizures. Another important feature of SSW is the flameus nevus on the face. In the oral cavity, SSW appears as hemangiomatous lesions affecting the mucous membranes and occasionally the dental pulp. Gingival hyperplasia may be present due to the use of anticonvulsant drugs. The present article reports the m...
Source: Journal of Craniofacial Surgery - January 1, 2021 Category: Surgery Tags: Brief Clinical Studies Source Type: research

Robot-assisted coronary artery bypass surgery: a systematic review and meta-analysis of comparative studies.
CONCLUSION: Although the findings from this review of comparative studies of RCAB appear promising and suggest that RCAB may offer some benefits to patients, in the absence of randomized controlled trials, these results should be interpreted cautiously. PMID: 33155975 [PubMed - in process]
Source: Canadian Journal of Surgery - November 1, 2020 Category: Surgery Authors: Hammal F, Nagase F, Menon D, Ali I, Nagendran J, Stafinski T Tags: Can J Surg Source Type: research

Blunt cerebrovascular injury: The case for universal screening
CONCLUSION Almost 20% of patients with BCVI, including a quarter of those with BCVI grade 3 or higher, would have gone undiagnosed by even the most extensive and sensitive BCVI screening criteria. Implementation of universal screening should strongly be considered to ensure the detection of all clinically relevant BCVIs. LEVEL OF EVIDENCE Diagnostic study, level III.
Source: Journal of Trauma and Acute Care Surgery - October 27, 2020 Category: Surgery Tags: WTA PODIUM - 2020 Source Type: research

Protamine Reduces Serious Bleeding Complications Associated with Carotid Endarterectomy in Asymptomatic Patients without Increasing the Risk of Stroke, Myocardial Infarction, or Death in a Large National Analysis.
CONCLUSION: Protamine reduces serious bleeding complications at the time of CEA without increasing the risk of MI, stroke, or death, in this large North American analysis. Based on this and previous regional work regarding protamine use in CEA, it is believed that there is now sufficient evidence to support its routine use, and it should be considered as a benchmark for quality during CEA. PMID: 33127243 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - October 27, 2020 Category: Surgery Authors: Stone DH, Giles KA, Kubilis P, Suckow BD, Goodney PP, Huber TS, Powell RJ, Cronenwett JL, Scali ST Tags: Eur J Vasc Endovasc Surg Source Type: research

Protamine Reduces Serious Bleeding Complications Associated with Carotid Endarterectomy in Asymptomatic Patients without Increasing the Risk of Stroke, Myocardial Infarction, or Death in a Large National Analysis
Controversy persists regarding the use of protamine during carotid endarterectomy (CEA), despite real world evidence to support its use. The purpose of this study was to determine the impact of protamine reversal of heparin anticoagulation on the outcome of CEA in the USA.
Source: European Journal of Vascular and Endovascular Surgery - October 27, 2020 Category: Surgery Authors: David H. Stone, Kristina A. Giles, Paul Kubilis, Bjoern D. Suckow, Philip P. Goodney, Thomas S. Huber, Richard J. Powell, Jack L. Cronenwett, Salvatore T. Scali Source Type: research

Editor's Choice – Protamine Reduces Serious Bleeding Complications Associated with Carotid Endarterectomy in Asymptomatic Patients without Increasing the Risk of Stroke, Myocardial Infarction, or Death in a Large National Analysis
Controversy persists regarding the use of protamine during carotid endarterectomy (CEA), despite real world evidence to support its use. The purpose of this study was to determine the impact of protamine reversal of heparin anticoagulation on the outcome of CEA in the USA.
Source: European Journal of Vascular and Endovascular Surgery - October 27, 2020 Category: Surgery Authors: David H. Stone, Kristina A. Giles, Paul Kubilis, Bjoern D. Suckow, Philip P. Goodney, Thomas S. Huber, Richard J. Powell, Jack L. Cronenwett, Salvatore T. Scali Tags: National Registry Source Type: research

Antimalarial and cytotoxic drugs on COVID-19 and the cardiovascular burden: Literature review and lessons to be learned.
DISCUSSION: There is no convincing clinical evidence of chloroquine, hydroxychloroquine with or without azithromycin, and remdesivir use in COVID-19. As evidence of systemic inflammation is rapidly unfolding, there is a dire need to maximize our resources to find the best possible solutions to the current crisis while conclusive evidence from clinical trials emerges. PMID: 32691699 [PubMed - as supplied by publisher]
Source: Vascular - July 20, 2020 Category: Surgery Authors: Sultan S, Acharya Y Tags: Vascular Source Type: research

Synchronous versus staged carotid artery stenting and coronary artery bypass graft for patients with concomitant severe coronary and carotid artery stenosis: A systematic review and meta-analysis.
CONCLUSION: The simultaneous approach was associated with an increased risk of 30-day stroke compared to staged CAS and CABG. However, no statistically significant difference was found in long-term results of mortality, MI and stroke between the two approaches. Future studies are warranted to validate our results. PMID: 32493182 [PubMed - as supplied by publisher]
Source: Vascular - June 2, 2020 Category: Surgery Authors: Tzoumas A, Giannopoulos S, Charisis N, Texakalidis P, Kokkinidis DG, Zisis SN, Machinis T, Koullias GJ Tags: Vascular Source Type: research

Protamine sulfate use during tibial bypass does not appear to increase thrombotic events or affect short-term graft patency.
CONCLUSIONS: Heparin reversal with protamine sulfate after tibial or peroneal bypass grafting is not associated with higher cardiovascular morbidity, bypass thrombosis, amputation, or mortality. Additionally, there was no statistically significant difference in post-operative bleeding or thrombosis complications for patients who did not receive protamine, although the findings are suggestive of a potential difference in a more adequately powered study. Our results suggest that protamine sulfate is safe for intraoperative use without increased risk of thrombotic complications or early tibial bypass graft failure. PMID:...
Source: Vascular - May 10, 2020 Category: Surgery Authors: Phair J, Futchko J, Trestman EB, Carnevale M, Friedmann P, Shukla H, Garg K, Koleilat I Tags: Vascular Source Type: research

Protamine use in transcarotid artery revascularization is associated with lower risk of bleeding complications without higher risk of thromboembolic events
Recent studies have found that transcarotid artery revascularization (TCAR) is associated with lower risk of stroke or death compared with transfemoral carotid artery stenting but higher risk of bleeding complications, presumably associated with the need for an incision. Heparin anticoagulation is universally used during TCAR, so protamine use may reduce bleeding complications. However, the safety and effectiveness of protamine use in TCAR are unknown. We therefore evaluated the impact of protamine use on perioperative outcomes after TCAR in the Vascular Quality Initiative TCAR Surveillance Project.
Source: Journal of Vascular Surgery - April 5, 2020 Category: Surgery Authors: Patric Liang, Raghu L. Motaganahalli, Mahmoud B. Malas, Grace J. Wang, Jens Eldrup-Jorgensen, Jack L. Cronenwett, Brian W. Nolan, Vikram S. Kashyap, Marc L. Schermerhorn Source Type: research

Drain placement confers no benefit after carotid endarterectomy in the Vascular Quality Initiative
Whereas bleeding complications requiring a return to the operating room (OR) after carotid endarterectomy (CEA) are infrequent (1%), they are associated with an increased 30-day combined postoperative stroke or death rate. Drain placement after CEA varies among vascular surgeons, and there are limited data to support the practice. The goal of this study was to evaluate factors leading to drain placement and the effect of drains on postoperative outcomes including return to OR for bleeding, stroke, and death.
Source: Journal of Vascular Surgery - February 11, 2020 Category: Surgery Authors: Christopher J. Smolock, Katherine L. Morrow, Jeanwan Kang, Rebecca L. Kelso, James F. Bena, Daniel G. Clair Source Type: research

Protamine Reduces the Risk of Serious Bleeding at the Time of CEA without Increased Risk of Stroke, MI or Death
Introduction: Controversy persists regarding the use of Protamine during carotid endarterectomy (CEA) despite real world evidence to support its use. The purpose of this study was to best determine the impact of protamine reversal of heparin anticoagulation on the outcome of CEA throughout the United States.
Source: European Journal of Vascular and Endovascular Surgery - November 30, 2019 Category: Surgery Authors: David Stone, Kristina Giles, Bjoern Suckow, Philip Goodney, Thomas Huber, Richard Powell, Jack Cronenwett, Salvatore Scali Source Type: research

LEA 24. Synthetic Marijuana and Acute Lower Limb Thromboembolism and Ischemia —A Case Report
Synthetic marijuana use has been reported in the last years as a possible causative factor of different cardiovascular events, including myocardial infarction, ischemic stroke, intracranial bleeding, and cerebral vasospasm. One case of aortic thrombosis was also reported, but that was in a patient using cocaine and synthetic marijuana together. A case of lower limb thromboembolism and synthetic marijuana use has not been reported to date. Intoxication, material impurity, blood vessel reactivity, and chemical interaction with other drugs have been proposed as possible mechanisms of these events.
Source: Journal of Vascular Surgery - October 21, 2019 Category: Surgery Authors: Asaf Rabin Source Type: research

Use of Machine Learning for Prediction of Patient Risk of Postoperative Complications After Liver, Pancreatic, and Colorectal Surgery
ConclusionMachine learning was used to develop an algorithm that accurately predicted patient risk of developing complications following liver, pancreatic, or colorectal surgery. The algorithm had very  good predictive ability to predict specific complications and demonstrated superiority over other established methods.
Source: Journal of Gastrointestinal Surgery - August 4, 2019 Category: Surgery Source Type: research

Cervical Debranching in the Endovascular Era: A Single Centre Experience.
CONCLUSION: The results of cervical debranching procedures showed not only excellent patency rates, but also a significant rate of local complications. Carotid-subclavian bypass appeared to be safer with significantly fewer post-operative complications. Staged hybrid procedures also seemed to be safer. PMID: 31204185 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - June 12, 2019 Category: Surgery Authors: Konstantinou N, Debus ES, Vermeulen CFW, Wipper S, Diener H, Larena-Avellaneda A, Kölbel T, Tsilimparis N Tags: Eur J Vasc Endovasc Surg Source Type: research