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Specialty: Surgery
Condition: Bleeding

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Total 190 results found since Jan 2013.

Systemic thrombolysis increases hemorrhagic stroke risk without survival benefit compared with catheter-directed intervention for the treatment of acute pulmonary embolism
Conclusions ST for acute PE may not improve in-hospital mortality compared with CDI but increases the overall risk of hemorrhagic stroke compared with CDI. Further prospective studies should examine the comparative effectiveness and safety of these two treatments.
Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders - January 15, 2017 Category: Surgery Source Type: research

STRAUMA: A Novel Alert System for a Combined Stroke and Trauma
CONCLUSION: The novel STRAUMA activation allows for an evaluation of both stroke and trauma to facilitate safe and timely administration of lifesaving interventions.PMID:35773229 | DOI:10.1177/00031348221111510
Source: The American Surgeon - June 30, 2022 Category: Surgery Authors: Janet S Lee Heather Finch Kelly Higa Abid D Khan Janice Millar Jonathan O'Neil Chamisa MacIndoe Valerie Brockman Donna Stringer Thomas J Schroeppel Source Type: research

Protamine Reduces Serious Bleeding Complications Associated with Carotid Endarterectomy in Asymptomatic Patients without Increasing the Risk of Stroke, Myocardial Infarction, or Death in a Large National Analysis.
CONCLUSION: Protamine reduces serious bleeding complications at the time of CEA without increasing the risk of MI, stroke, or death, in this large North American analysis. Based on this and previous regional work regarding protamine use in CEA, it is believed that there is now sufficient evidence to support its routine use, and it should be considered as a benchmark for quality during CEA. PMID: 33127243 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - October 27, 2020 Category: Surgery Authors: Stone DH, Giles KA, Kubilis P, Suckow BD, Goodney PP, Huber TS, Powell RJ, Cronenwett JL, Scali ST Tags: Eur J Vasc Endovasc Surg Source Type: research

Deep Vein Thrombosis After Total Hip Arthroplasty and Total Knee Arthroplasty in Patients With Previous Ischemic Stroke
The present study evaluated the prevalence and therapy of deep vein thrombosis (DVT) after total hip arthroplasty (THA) and total knee arthroplasty (TKA) in 57 patients with previous ischemic stroke. Postoperative anticoagulants were used for DVT prophylaxis, and batroxobin and prolonged anticoagulants were used for thrombolysis in DVT subjects. The incidence of DVT after THA and TKA in patients with previous ischemic stroke was 16.2% and 20%, respectively. No bleeding complications were observed and no new ischemic stroke occurred during the following 3 months. The prevalence DVT after THA and TKA in patients with previou...
Source: The International Journal of Lower Extremity Wounds - December 17, 2013 Category: Surgery Authors: Qin, J., Xu, Z., Shi, D., Chen, D., Dai, J., Teng, H., Jiang, Q. Tags: Clinical Research Source Type: research

Protamine Reduces Bleeding Complications without Increasing the Risk of Stroke after Carotid Endarterectomy: A Meta-analysis.
CONCLUSION: On the basis of the available data, heparin reversal with protamine seems to reduce the risk of wound haematoma, without increasing the risk of procedural stroke. However, taking into account the limitations of the analysis, further studies are needed to increase the level of evidence provided by the current meta-analysis. PMID: 27389942 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - July 3, 2016 Category: Surgery Authors: Kakisis JD, Antonopoulos CN, Moulakakis KG, Schneider F, Geroulakos G, Ricco JB Tags: Eur J Vasc Endovasc Surg Source Type: research

Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in Chinese patients with atrial fibrillation.
In conclusion, oral administration of rivaroxaban reduced the risk of stroke or systemic embolism without significantly increasing the safety concern. PMID: 23929423 [PubMed - as supplied by publisher]
Source: Vascular - June 18, 2013 Category: Surgery Authors: Mao L, Li C, Li T, Yuan K Tags: Vascular Source Type: research

Prevention of Stroke With Ticagrelor in Patients With Prior Myocardial Infarction: Insights from PEGASUS-TIMI 54 (Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin-Thrombolysis in Myocardial Infarction)
In patients with prior myocardial infarction, ticagrelor 60  mg twice daily reduces risk of stroke without an excess of hemorrhagic stroke but with more major bleeding.
Source: Journal of Vascular Surgery - December 20, 2016 Category: Surgery Authors: M.P. Bonaca, S. Goto, D.L. Bhatt Tags: Abstract Source Type: research

Dual Antiplatelet Therapy Is Associated with Increased Risk of Bleeding and Decreased Risk of Stroke Following Carotid Endarterectomy
Despite many patients undergoing carotid endarterectomy (CEA) being on dual antiplatelet therapy (DAPT) for cardiac or neurologic indications, the impact of such therapy on perioperative outcomes remains unclear. We aim to compare rates of postoperative bleeding, stroke and major adverse events (stroke, death or MI) among patients on Aspirin alone (ASAA) versus DAPT (Clopidogrel and Aspirin).
Source: Annals of Vascular Surgery - July 31, 2022 Category: Surgery Authors: Rohini J. Patel, Rebecca Marmor, Hanaa Dakour, Nadin Elsayed, Mokhshan Ramachandran, Mahmoud B. Malas Tags: Clinical Research Source Type: research

Bleeding, Transfusion and the Risk of Stroke after Coronary Surgery: A Prospective Cohort Study of 2,357 patients
This study was planned to investigate the impact of severe bleeding and blood transfusion on the development of stroke after coronary surgery.
Source: International Journal of Surgery - June 21, 2016 Category: Surgery Authors: Fausto Biancari, Tuomas Tauriainen, Andrea Perrotti, Magnus Dalén, Giuseppe Faggian, Ilaria Franzese, Sidney Chocron, Vito G. Ruggieri, Karl Bounader, Helmut Gulbins, Daniel Reichart, Peter Svenarud, Giuseppe Santarpino, Theodor Fischlein, Tamas Puski, D Tags: Original Research Source Type: research

Commentary on ‘Protamine Reduces Bleeding Complications Without Increasing the Risk of Stroke After Carotid Endarterectomy: A Meta-analysis’
Kakisis et al. demonstrate in their meta-analysis that reversing the effect of heparin with protamine seems to reduce the number of major neck hematomas associated with CEA. One might fear that this would be at the cost of an increased level of cerebral thromboembolism. However, Kakisis et al. showed that administration of protamine does not seem to influence the rate of stroke.1
Source: European Journal of Vascular and Endovascular Surgery - July 13, 2016 Category: Surgery Authors: L.K. Rathenborg Tags: Invited Commentary Source Type: research

Commentary on 'Protamine Reduces Bleeding Complications Without Increasing the Risk of Stroke After Carotid Endarterectomy: A Meta-analysis'.
PMID: 27424007 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - July 12, 2016 Category: Surgery Authors: Rathenborg LK Tags: Eur J Vasc Endovasc Surg Source Type: research

Commentary on ‘Protamine Reduces Bleeding Complications Without Increasing the Risk of Stroke After Carotid Endarterectomy: A Meta-analysis’
Kakisis et  al. demonstrate in their meta-analysis that reversing the effect of heparin with protamine seems to reduce the number of major neck hematomas associated with CEA. One might fear that this would be at the cost of an increased level of cerebral thromboembolism. However, Kakisis et al. showed that a dministration of protamine does not seem to influence the rate of stroke.1
Source: European Journal of Vascular and Endovascular Surgery - July 13, 2016 Category: Surgery Authors: L.K. Rathenborg Tags: Invited Commentary Source Type: research