Commentary on ‘Protamine Reduces Bleeding Complications Without Increasing the Risk of Stroke After Carotid Endarterectomy: A Meta-analysis’

Kakisis et al. demonstrate in their meta-analysis that reversing the effect of heparin with protamine seems to reduce the number of major neck hematomas associated with CEA. One might fear that this would be at the cost of an increased level of cerebral thromboembolism. However, Kakisis et al. showed that administration of protamine does not seem to influence the rate of stroke.1
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Tags: Invited Commentary Source Type: research