Master Techniques in Surgery: Breast Surgery
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: BOOK REVIEWS Source Type: research

Surgery Boot Camp Manual: A Multimedia Guide for Surgical Training
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: BOOK REVIEWS Source Type: research

Master Techniques in Surgery: Hepatobiliary and Pancreatic Surgery, 2nd Edition
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: BOOK REVIEWS Source Type: research

Clinical Scenarios in Surgery: Decision Making and Operative Technique
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: BOOK REVIEWS Source Type: research

Cleveland Clinic Illustrated Tips and Tricks in Colon and Rectal Surgery
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: BOOK REVIEWS Source Type: research

The Association Between Symptoms and COVID-19 Test Results Among Healthcare Workers
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: COVID-19 Source Type: research

Postoperative Onset and Detection of SARS-CoV-2 in Surgically Resected Specimens From Gastrointestinal Cancer Patients With Pre/Asymptomatic COVID-19
Conclusions: Gastrointestinal cancer patients with pre/asymptomatic COVID-19 were at high risk of postoperative onset and death. At current pandemic, elective surgery should be postponed or canceled. It highlights the need for investigating the full clinical spectrum and natural history of this infection. The early colorectal tropism of SARS-CoV-2 may have major implications on prevention, diagnosis, and treatment of COVID-19. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: COVID-19 Source Type: research

Results of COVID-minimal Surgical Pathway During Surge-phase of COVID-19 Pandemic
Conclusions: A COVID-minimal pathway comprised of physical space modifications and operational changes may allow urgent cancer treatment to safely continue during the COVID-19 pandemic, even during the surge-phase. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: COVID-19 Source Type: research

Prone Positioning for Severe Acute Respiratory Distress Syndrome in COVID-19 Patients by a Dedicated Team: A Safe and Pragmatic Reallocation of Medical and Surgical Work Force in Response to the Outbreak
Conclusions: To overcome the surge of critically ill COVID-19 patients, reallocating health care workers to targeted medical tasks beyond their respective expertise such as PP was safe. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: COVID-19 Source Type: research

The Impact of Telemedicine Adoption on a Multidisciplinary Bariatric Surgery Practice During the COVID-19 Pandemic
This study aims to show how full-time telemedicine adoption has impacted patient visit volume and attendance in a comprehensive metabolic and weight loss center. Summary Background Data: Elective surgical practices have been profoundly impacted by the global COVID-19 pandemic, leading to a rapid increase in the utilization of telemedicine. The abrupt initiation of audio-video telehealth visits for all providers of a multidisciplinary clinic on March 19th 2020 provided unique circumstances to assess the impact of telemedicine. Methods: Data from the clinical booking system (new patient and follow-up visits) fo...
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: COVID-19 Source Type: research

Critical Considerations for Reopening Scheduled Surgical Care in the Setting of the COVID-19 Pandemic: A Framework for Implementation
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: COVID-19 Source Type: research

Reducing Moral Distress in the Setting of a Public Health Crisis
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: COVID-19 Source Type: research

Planning the Full Recovery Phase: An Antifragile Perspective on Surgery After COVID-19
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: COVID-19 Source Type: research

Elective Surgery and COVID-19: A Framework for the Untested Patient
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: COVID-19 Source Type: research

Pancreatic Cancer Prognostication: From Trousseau to Thrombelastography
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: BRIEF CLINICAL REPORTS Source Type: research

Thrombelastography as a Prognostic Tool in Adenocarcinoma of the Pancreas
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: BRIEF CLINICAL REPORTS Source Type: research

A Framework for the Future
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: BRIEF CLINICAL REPORTS Source Type: research

Parathyroidectomy for Mild Hyperparathyroidism in the Octogenarian: Is Age Really Just a Number?
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: BRIEF CLINICAL REPORTS Source Type: research

A Tale of Two Livers
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: BRIEF CLINICAL REPORTS Source Type: research

Liver Paired Exchange Using Compatible Pairs – US Single Center Experience
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: BRIEF CLINICAL REPORTS Source Type: research

System Factors Affecting Intraoperative Risk and Resilience: Applying a Novel Integrated Approach to Study Surgical Performance and Patient Safety
Conclusions: Safety threats and resilience supports were found to be systematic in the surgical setting. Identified safety threats should be prioritized for remediation, and clinician behaviors that contribute to fostering resilience should be valued and protected. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Nontechnical Skill Assessment of the Collective Surgical Team Using the Non-Technical Skills for Surgeons (NOTSS) System
Conclusion: The NOTSS system, although developed for assessment of individual surgeons, is a useful tool for observing and rating surgical teams. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Opioid Prescription Patterns for Children Following Laparoscopic Appendectomy
Conclusions: There was substantial variation in opioid prescribing patterns. Opioid prescription duration increased risk of ED visits for constipation, but not for pain or refill. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Metabolic Systems Analysis of Shock-Induced Endotheliopathy (SHINE) in Trauma: A New Research Paradigm
Conclusions: We confirm that trauma patients have a significantly different metabolic profile compared with controls. A minimum of 4 shock-induced endotheliopathy phenotypes were identified, which were independent of syndecan-1level (except 1 phenotype) verifying that the endothelial response to trauma is heterogeneous and most likely driven by a genetic component. Moreover, we introduced a new research tool in trauma by using metabolic systems biology, laying the foundation for personalized medicine. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Utilizing Machine Learning Methods for Preoperative Prediction of Postsurgical Mortality and Intensive Care Unit Admission
Conclusions: Machine learning can be used to improve surgical risk prediction compared to traditional risk calculators. AUPRC should be used to evaluate model predictive performance instead of AUROC when the dataset is imbalanced. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

The Primary Aldosteronism Surgical Outcome Score for the Prediction of Clinical Outcomes After Adrenalectomy for Unilateral Primary Aldosteronism
Conclusions: The predictive score and the primary aldosteronism surgical outcome predictor can be used in a clinical setting to differentiate patients who are likely to be clinically cured after surgery from those who will need continuous surveillance after surgery due to persistent hypertension. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Main Duct Dilatation Is the Best Predictor of High-grade Dysplasia or Invasion in Intraductal Papillary Mucinous Neoplasms of the Pancreas
Conclusions: In agreement with current IPMN management guidelines, we found MPD dilatation, even low levels from 5 mm to 9.9 mm, to be the single best predictor of HG-IPMN or invasion, highlighting the critical role that MPD plays in the selection of surgical candidates. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Drain Management Following Distal Pancreatectomy: Characterization of Contemporary Practice and Impact of Early Removal
Conclusion: Although not yet widely implemented, early drain removal after distal pancreatectomy is associated with better outcomes. This study demonstrates the potential benefits of early removal and provides a substrate to define best practices and improve the quality of care for DP. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

County-level Variation in Use of Surgery and Cancer-specific Survival for Stage I-II Pancreatic Adenocarcinoma
Objective: The aim of the study was to describe county-level variation in use of surgery for stage I-II pancreatic ductal adenocarcinoma (PDAC) and the association between county surgery rates and cancer-specific survival (CSS). Background: The degree of small geographic area variation in use of surgery for stage I-II PDAC and the association between area surgery rates and CSS remain incompletely defined. Methods: This is a retrospective cohort study of patients aged 18 to 80 years in the 2007 to 2015 Surveillance, Epidemiology, and End Results database with stage I-II PDAC without contraindications to su...
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Metastatic Potential and Survival of Duodenal and Pancreatic Tumors in Multiple Endocrine Neoplasia Type 1: A GTE and AFCE Cohort Study (Groupe d’étude des Tumeurs Endocrines and Association Francophone de Chirurgie Endocrinienne)
Conclusions: DP-NETs of 2 cm in size or more, regardless of the associated secretion, should be removed to prevent metastasis and increase survival. Surgery for gastrinoma remains debatable. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Histopathologic Predictors of Survival and Recurrence in Resected Ampullary Adenocarcinoma: International Multicenter Cohort Study
Conclusions: Independent predictors of OS in resected ampullary cancer were N-stage, perineural invasion, and adjuvant chemotherapy. N-stage was the only predictor of DFS. These findings improve predicting survival and recurrence after resection of ampullary adenocarcinoma. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

APC and PIK3CA Mutational Cooperativity Predicts Pathologic Response and Survival in Patients Undergoing Resection for Colorectal Liver Metastases
Objective: The aim of the study was to determine the prognostic impact of co-existence of APC and PIK3CA mutations in patients undergoing preoperative chemotherapy and resection for colorectal liver metastases (CLM). Background: Co-occurring genetic events have been shown to drive carcinogenesis in multiple malignancies. Methods: We identified 396 patients with primary colorectal cancer and known somatic mutation status by next-generation sequencing who underwent hepatectomy for CLM (2005–2015). Survival after hepatectomy in patients with double mutation of APC and PIK3CA and others was analyzed. Pr...
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Females Are More Resistant to Ischemia-Reperfusion-induced Intestinal Injury Than Males: A Human Study
Conclusion: The human female small intestine seems less susceptible to IR-induced tissue injury than the male small intestine. Recognition of such differences could lead to the development of novel therapeutic strategies to reduce IR-associated morbidity and mortality. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Neoadjuvant Radiotherapy Versus Surgery Alone for Stage II/III Mid-low Rectal Cancer With or Without High-risk Factors: A Prospective Multicenter Stratified Randomized Trial
Objective: The aim of this study was to compare stage II/III rectal cancers with or without high-risk factors, and evaluate the effect of neoadjuvant radiotherapy (NRT) in these 2 cohorts. Background: NRT is often used in stage II/III rectal cancers to improve local control, while not affecting overall survival. However, good-quality surgery without NRT may also achieve good local control in selected patients. Methods: According to risk-stratification criteria and clinical staging, consecutive eligible participants of stage II/III rectal cancer were preoperatively classified into patients with (high-risk)...
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Bariatric Surgery is Associated With Reduced Risk of Breast Cancer in Both Premenopausal and Postmenopausal Women
Conclusions: Bariatric surgery was associated with a reduced risk of breast cancer among severely obese women. These findings have significant public health relevance because the prevalence of obesity continues to rise, and few modifiable breast cancer risk factors have been identified, especially for premenopausal women. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Patient Behaviors and Characteristics Related to Weight Regain After Roux-en-Y Gastric Bypass: A Multicenter Prospective Cohort Study
Objective: To identify patient behaviors and characteristics related to weight regain after Roux-en-Y gastric bypass surgery (RYGB). Background: There is considerable variation in the magnitude of weight regain after RYGB, highlighting the importance of patient-level factors. Methods: A prospective cohort study of adults who underwent bariatric surgery in 6 US cities between 2006 and 2009 included presurgery, and 6-month and annual assessments for up to 7 years. Of 1573 eligible participants, 1278 (81%) with adequate follow-up were included (80% female, median age 46 years, median body mass index 46 kg/...
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Influence of Preoperative Oropharyngeal Microflora on the Occurrence of Postoperative Pneumonia and Survival in Patients Undergoing Esophagectomy for Esophageal Cancer
This study included 675 patients who underwent esophagectomy between 2007 and 2014. Saliva samples from the oropharynx were collected 2 days before the operation. There were 442 patients with indigenous flora (Ind group) and 233 with allopatric flora. Among the patients with allopatric flora, 140 had antibiotic-sensitive microbes only (Allo-S group) while 93 had different types of antibiotic-resistant microbes (Allo-R group). We investigated the correlation between the types of oropharyngeal microflora and the incidence of postoperative complications as well as long-term outcomes. Results: Sixteen microbes could be ...
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Tumor Long-interspersed Nucleotide Element-1 Methylation Level and Immune Response to Esophageal Cancer
Conclusions: Tumor LINE-1 hypomethylation level is associated with a diminished peritumoral lymphocytic reaction, providing impetus for further investigations on potential interactive roles of tumor LINE-1 hypomethylation and host immunity in esophageal cancer development. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Recertification Exam Performance in General Surgery is Associated With Subsequent Loss of License Actions
Conclusions: Failing the first recertification exam attempt was associated with a greater rate of subsequent loss-of-license actions. These results suggest that demonstrating sufficient surgical knowledge is a significant predictor of future loss-of-license actions. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Video-based Learning in Surgery: Establishing Surgeon Engagement and Utilization of Variable-duration Videos
Objective: To measure surgeon engagement and preferred video duration in a video-based learning program for nerve surgery. Background: Educational videos can improve, standardize, and democratize best practices in surgery. To improve care internationally, educators must optimize their videos for learning. However, surgeon engagement and optimal video duration remain undefined. Methods: A YouTube channel and a video-based learning website, PASSIO Education (passioeducation.com), were examined from 2011 to 2017. We assessed views, geographic location, audience engagement (average percent of video watched), ...
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Concordance Between Registry and Administrative Data in the Determination of Comorbidity: A Multi-institutional Study
Objective: To characterize agreement between administrative and registry data in the determination of patient-level comorbidities. Background: Previous research finds poor agreement between these 2 types of data in the determination of outcomes. We hypothesized that concordance between administrative and registry data would also be poor. Methods: A cohort of inpatient operations (length of stay 1 day or greater) was obtained from a consortium of 8 hospitals. Within each hospital, National Surgical Quality Improvement Program (NSQIP) data were merged with intra-institutional inpatient administrative data. ...
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Recalibration and External Validation of the Risk Analysis Index: A Surgical Frailty Assessment Tool
Objective and Background: The Risk Analysis Index (RAI) predicts 30-, 180-, and 365-day mortality based on variables constitutive of frailty. Initially validated, in a single-center Veteran hospital, we sought to improve model performance by recalibrating the RAI in a large, veteran surgical registry, and to externally validate it in both a national surgical registry and a cohort of surgical patients for whom RAI was measured prospectively before surgery. Methods: The RAI was recalibrated among development and confirmation samples within the Veterans Affairs Surgical Quality Improvement Program (VASQIP; 2010&nda...
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

The Carbon Footprint of Surgical Operations: A Systematic Review
Conclusions: Future research should focus on optimizing the carbon footprint of operating theatres through streamlining operations, expanding assessments to other surgical contexts, and determining ways to reduce the footprint through targeting carbon hotspots. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: REVIEW PAPERS Source Type: research

Detecting the Near Infrared Autofluorescence of the Human Parathyroid: Hype or Opportunity?
Conclusions: Because NIRAF-based identification of PG is noninvasive and label-free, the popularity of this approach has considerably surged. As the present limitations of various technologies capable of NIRAF detection are identified, we anticipate that newer device iterations will continue to be developed enhancing the current merits of these modalities to aid surgeons in identifying and preserving PGs. However, more concrete and long-term outcome studies with these modalities are essential to determine the impact of this technique on patient outcome and actual cost-benefits. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: REVIEW PAPERS Source Type: research

The Effect of Perioperative Music on Medication Requirement and Hospital Length of Stay: A Meta-analysis
This study was registered with PROSPERO (CRD42018093140) and adhered to the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines. Results: The literature search yielded 2414 articles, 55 studies (N = 4968 patients) were included. Perioperative music significantly reduced postoperative opioid requirement (pooled SMD −0.31 [95% CI −0.45 to −0.16], P (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: META-ANALYSIS Source Type: research

Primary Open Versus Closed Implantation Strategy for Totally Implantable Venous Access Ports: The Multicentre Randomized Controlled PORTAS-3 Trial (DRKS 00004900)
Conclusion: A primary open strategy by cut-down of the cephalic vein, if necessary enhanced by a modified Seldinger technique, reduces the frequency of pneumothorax or haemothorax after central venous port implantation significantly compared with a closed strategy by primary puncture of the subclavian vein without routine sonographic guidance. Therefore, open surgical cut-down should be the reference standard for port implantation in comparable cohorts. Trial Registration: German Clinical Trials Register DRKS 00004900. (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: RANDOMIZED CONTROLLED TRIALS Source Type: research

The Influence of Perioperative Fluid Therapy on N-terminal-pro-brain Natriuretic Peptide and the Association With Heart and Lung Complications in Patients Undergoing Colorectal Surgery: Secondary Results of a Clinical Randomized Assessor-blinded Multicenter Trial
Objective: To investigate the influence of intravenous (iv) fluid volumes on the secretion of N-terminal-pro-brain natriuretic peptide (NT-Pro-BNP) in colorectal surgical patients and its association with cardiopulmonary complications (CPC). In addition, to examine if preoperative NT-Pro-BNP can predict the risk for postoperative CPC. Methods: Blood samples from patients enrolled in a previously published clinical randomized assessor-blinded multicenter trial were analyzed.1 Included were adult patients undergoing elective colorectal surgery with the American-Society-of-Anesthesiologists-scores of 1–3. Sam...
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: RANDOMIZED CONTROLLED TRIALS Source Type: research

Ensuring Equal Access to Mentorship and Sponsorship for Surgeons Through Structured Team-based Mentoring
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: COVID-19 - SURGICAL PERSPECTIVES Source Type: research

Responding to Unexpected Crises – The Role of Surgical Leadership
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: COVID-19 - SURGICAL PERSPECTIVES Source Type: research

Defining Domains of Survivorship
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - November 30, 2020 Category: Surgery Tags: COVID-19 - SURGICAL PERSPECTIVES Source Type: research