An International Cohort Study of Prognosis Associated With Pathologically Complete Response Following Neoadjuvant Chemotherapy Versus Chemoradiotherapy of Surgical Treated Esophageal Adenocarcinoma
Conclusions:
The results of this international cohort study show that the prognosis of pCR following different neoadjuvant regimes differs, bringing into question the validity of this measure as an oncological surrogate when comparing neoadjuvant treatment schemes for esophageal adenocarcinoma. (Source: Annals of Surgery)
Source: Annals of Surgery - October 15, 2022 Category: Surgery Tags: ESA Paper Source Type: research
CROSS Versus FLOT Regimens in Esophageal and Esophagogastric Junction Adenocarcinoma: A Propensity-Matched Comparison
Background:
The FLOT protocol and the CROSS trimodality regimen represent current standards in the management of locally advanced esophageal adenocarcinoma. In the absence of published Randomised Controlled Trial data, this propensity-matched comparison evaluated tolerance, toxicity, impact on sarcopenia and pulmonary physiology, operative complications, and oncologic metrics.
Methods:
Two hundred and twenty-two patients, 111 in each arm, were included from 2 high-volume centers. Computed tomography-measured sarcopenia, and pulmonary function (forced expiratory volume in first second/forced vital capacity/diffus...
Source: Annals of Surgery - October 15, 2022 Category: Surgery Tags: ESA Paper Source Type: research
A Novel Tumor Staging System Incorporating Tumor Regression Grade (TRG) With Lymph Node Status (ypN-Category) Results in Better Prognostication Than ypTNM Stage Groups After Neoadjuvant Therapy for Esophageal Squamous Cell Carcinoma
Conclusion:
TRG-N stage shows better prognostication than the AJCC postneoadjuvant therapy (ypTNM) stage groups. (Source: Annals of Surgery)
Source: Annals of Surgery - October 15, 2022 Category: Surgery Tags: ESA Paper Source Type: research
Machine Learning Risk Prediction Model of 90-day Mortality After Gastrectomy for Cancer
Conclusions:
A robust clinical model for predicting the risk of 90DM after surgery of gastric cancer was developed. Its use may aid patients and surgeons in making informed decisions. (Source: Annals of Surgery)
Source: Annals of Surgery - October 15, 2022 Category: Surgery Tags: ESA Paper Source Type: research
Effect of the Use of Reinforced Stapling on the Occurrence of Pancreatic Fistula After Distal Pancreatectomy: Results of the REPLAY (REinforcement of the Pancreas in distaL pAncreatectomY) Multicenter Randomized Clinical Trial
Conclusion:
The results of this randomized clinical trial did not favor the use of RS during DP to reduce the rate of PF. (Source: Annals of Surgery)
Source: Annals of Surgery - October 15, 2022 Category: Surgery Tags: ESA-Randomized Controlled Trial Source Type: research
The Role of Pelvic Floor Muscle Training on Low Anterior Resection Syndrome: A Multicenter Randomized Controlled Trial
Conclusions:
PFMT for bowel symptoms after TME resulted in lower proportions and faster recovery of bowel symptoms up to 6 months after surgery/stoma closure, justifying PFMT as an early, first-line treatment option for bowel symptoms after RC. (Source: Annals of Surgery)
Source: Annals of Surgery - October 15, 2022 Category: Surgery Tags: ESA-Randomized Controlled Trial Source Type: research
Alternative Randomized Trial Designs in Surgery: A Systematic Review
Introduction:
Randomized controlled trials (RCTs) yield the highest level of evidence but are notoriously difficult to perform in surgery. Surgical RCTs may be hampered by slow accrual, the surgical learning curve, and lack of financial support. Alternative RCT designs such as stepped-wedge randomized controlled trials (SW-RCTs), registry-based randomized controlled trials (RB-RCTs), and trials-within-cohorts (TwiCs) may overcome several of these difficulties. This review provides an overview of alternative RCT designs used in surgical research.
Methods:
We systematically searched PubMed, EMBASE, and Cochrane Ce...
Source: Annals of Surgery - October 15, 2022 Category: Surgery Tags: Special ESA Lecture 2022 Source Type: research
Towards a Virtual “Global Academia of Surgeons”
Conclusion:
E-learning can improve local academic training and promote the global visibility of strong academic centers. Providing free and unrestricted expertise via social media is a novel and groundbreaking opportunity that fills a global education gap by dissemination of surgical education on an unprecedented scale. Expert associations such as the ESA may adopt similar formats and foster their perception as true beacons of knowledge. (Source: Annals of Surgery)
Source: Annals of Surgery - October 15, 2022 Category: Surgery Tags: Special ESA Lecture 2022 Source Type: research
So, You Want to be a Surgeon?
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - October 15, 2022 Category: Surgery Tags: Presidential Address Source Type: research
Comment on “Birth of a Healthy Baby 9 Years After a Surgically Successful Deceased Donor Uterus Transplant”: Erratum
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - September 16, 2022 Category: Surgery Tags: Annals of Surgery Source Type: research
Outcomes for Physiologic Microsurgical Treatment of Secondary Lymphedema Involving the Extremity
Conclusions:
Patients with secondary UEL/LEL who undergo VLNT/LVB demonstrate improved functional status and reduced affected limb volumes postoperatively. Patients with UEL seem to have a more substantial reduction in limb volume differential compared to LEL patients. (Source: Annals of Surgery)
Source: Annals of Surgery - September 16, 2022 Category: Surgery Tags: Original Articles Source Type: research
Sarcopenia Aneurysm Scoring System Predicts Early and Midterm Mortality After Endovascular Repair for Abdominal Aortic Aneurysm
Conclusion:
We developed the SAS to predict all-cause mortality after elective EVAR and this scoring showed excellent predictive performance. (Source: Annals of Surgery)
Source: Annals of Surgery - September 16, 2022 Category: Surgery Tags: Original Articles Source Type: research
Complications and Failure to Rescue After Inpatient Pediatric Surgery
Objective:
To describe the frequency and patterns of postoperative complications and FTR after inpatient pediatric surgical procedures and to evaluate the association between number of complications and FTR.
Summary and Background:
FTR, or a postoperative death after a complication, is currently a nationally endorsed quality measure for adults. Although it is a contributing factor to variation in mortality, relatively little is known about FTR after pediatric surgery.
Methods:
Cohort study of 200,554 patients within the National Surgical Quality Improvement Program-Pediatric database (2012–2016) who und...
Source: Annals of Surgery - September 16, 2022 Category: Surgery Tags: Original Articles Source Type: research
Fate of Patients With Intraductal Papillary Mucinous Neoplasms of Pancreas After Resection According to the Pathology and Margin Status: Continuously Increasing Risk of Recurrence Even After Curative Resection Suggesting Necessity of Lifetime Surveillance
This study evaluated the associated factors and prognosis according to pathology and margin after surgical resection of intraductal papillary mucinous neoplasms (IPMN).
Background:
There is limited information on recurrence patterns according to pathology and margin in IPMN.
Methods:
Total 577 patients who underwent operation for IPMN at a tertiary center were included. Factors associated with recurrence, survival, and recurrence outcomes according to pathology and margin were analyzed.
Results:
Among 548 patients analyzed, 353 had low-grade dysplasia (LGD), 78 had high-grade dysplasia (HGD), and 117 h...
Source: Annals of Surgery - September 16, 2022 Category: Surgery Tags: Original Articles Source Type: research
Salvage of Declined Extended-criteria DCD Livers Using In Situ Normothermic Regional Perfusion
Conclusion:
aNRP can safely select and thus is able to rescue DCD liver grafts that were deemed unsuitable for transplantation, while preventing primary nonfunction and minimizing ischemic cholangiopathy. (Source: Annals of Surgery)
Source: Annals of Surgery - September 16, 2022 Category: Surgery Tags: Original Articles Source Type: research
