A More Extensive Lymphadenectomy Enhances Survival After Neoadjuvant Chemoradiotherapy in Locally Advanced Esophageal Adenocarcinoma
Conclusions:
The optimal extent of lymphadenectomy to enhance both staging and survival after chemoradiotherapy, regardless of treatment response, is approximately 25 lymph nodes. (Source: Annals of Surgery)
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Original Articles Source Type: research
Comprehensive Analysis of Multiple Primary Cancers in Patients With Esophageal Squamous Cell Carcinoma Undergoing Esophagectomy
This study consisted of 3 retrospective investigations. A total of 766 consecutive patients with ESCC who underwent esophagectomy between April 2005 and December 2019 were eligible for epidemiological analysis. Of these, 688 patients without missing data were analyzed for the risk of MPCs. In total, 364 patients who underwent NAC (115) and no preoperative treatments (249) were investigated for the association between NAC and PMC.
Results:
Of 766 patients, 288 (38%) patients experienced 357 MPCs in their life. PMCs identified after the completion of 5-year postoperative follow-up were significantly more advanced (P =...
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Original Articles Source Type: research
Distribution of Residual Disease and Recurrence Patterns in Pathological Responders After Neoadjuvant Chemotherapy for Esophageal Squamous Cell Carcinoma
This study aimed to elucidate the residual disease distribution and recurrence patterns in patients with ESCC responding to NAC.
Summary Background Data:
To appropriately plan a prospective trial for the organ preservation approach which includes additional chemoradiotherapy in patients who responded to NAC, the distribution of residual disease needs to be elucidated. Given that the residual tumor is located in the regional field, chemoradiotherapy can be safely added to eliminate the residual disease.
Methods:
Overall, 483 patients with resectable ESCC who received NAC followed by transthoracic esophagectomy...
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Original Articles Source Type: research
The Accumulating Deficits Model for Postoperative Mortality and Readmissions: Comparison of Four Methods Over Multiple Calendar Year Cohorts
Conclusions:
The 4 methods of calculating frailty performed similarly and were stable. The actual method of determining the accumulated deficits may not be as important as enumerating their number. (Source: Annals of Surgery)
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Original Articles Source Type: research
STOPS: A Coping Framework for Surgeons Who Experience Intraoperative Error
Conclusions and Relevance:
This study provides both novel insight into how surgeons cope with intraoperative errors and a framework that may be of great use to trainees and faculty alike. (Source: Annals of Surgery)
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Original Articles Source Type: research
Association Between American Board of Surgery Initial Certification and Medical Malpractice Payments
Conclusions:
Failing to obtain board certification was associated with a higher rate of medical malpractice payments. In addition, failing examinations in the certification examination process on the first attempt was also associated with higher rates of medical malpractice payments. This study provides further evidence that board certification is linked to potential indicators for patient outcomes and practice quality. (Source: Annals of Surgery)
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Original Articles Source Type: research
Orthopedic Surgery Causes Gut Microbiome Dysbiosis and Intestinal Barrier Dysfunction in Prodromal Alzheimer Disease Patients: A Prospective Observational Cohort Study
Conclusions:
Surgery exacerbates both preexisting microbiota dysbiosis and intestinal barrier dysfunction in pAD patients, all of which may be associated with systemic inflammation and, in turn, may lead to further cognitive deterioration. (Source: Annals of Surgery)
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Original Articles Source Type: research
The Problem of Appetite Loss After Major Abdominal Surgery: A Systematic Review
Conclusions:
Appetite loss after major abdominal surgery is common and associated with increased morbidity and reduced quality of life. Recent studies demonstrate the influence of reduced gastric volume and ghrelin secretion, and increased satiety hormone secretion. There are various treatment options available including level IA evidence for postoperative gum chewing. In the future, surgical trials should include the assessment of appetite loss as a relevant outcome measure. (Source: Annals of Surgery)
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Review Papers Source Type: research
Early Barriers to Career Progression of Women in Surgery and Solutions to Improve Them: A Systematic Scoping Review
Conclusions:
Identification and recognition of obstacles to career progression is the first step to addressing the gender gap in surgery. Active strategies should be improved to promote a culture of diversity and to create equal opportunity for women in surgery, while implementing structured mentoring programs and investing on an adequate communication on social media to engage the future generations. (Source: Annals of Surgery)
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Review Papers Source Type: research
Safety of Intraoperative Blood Salvage During Liver Transplantation in Patients With Hepatocellular Carcinoma: A Systematic Review and Meta-analysis
Conclusions:
Based on available observational data, use of IBS during liver transplantation in patients with HCC does not result in impaired disease-free survival, increased HCC recurrence or impaired overall survival. Therefore, use of IBS during liver transplantation for HCC patients is a safe procedure. (Source: Annals of Surgery)
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Meta-Analysis Source Type: research
Moderate to Severe Soft Tissue Diabetic Foot Infections: A Randomized, Controlled, Pilot Trial of Post-debridement Antibiotic Treatment for 10 versus 20 days
Conclusions:
In this randomized, controlled pilot trial, post-debridement antibiotic therapy for soft tissue DFI for 10 days gave similar (and non-inferior) rates of remission and AEs to 20 days. A larger confirmatory trial is under way.
Trial registration:
ClinicalTrials NCT03615807. (Source: Annals of Surgery)
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Randomized Controlled Trials Source Type: research
The Efficacy of Liposomal Bupivacaine on Postoperative Pain Following Abdominal Wall Reconstruction: A Randomized, Double-blind, Placebo-controlled Trial
Conclusions:
There are no apparent clinical benefits to using liposomal bupivacaine transversus abdominis plane block when compared with simple bupivacaine and placebo for open abdominal wall reconstruction. (Source: Annals of Surgery)
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Randomized Controlled Trials Source Type: research
Prediction of R Status in Resections for Pancreatic Cancer Using Simplified Radiological Criteria: Not So Simple
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Features Source Type: research
Prediction of R Status in Resections for Pancreatic Cancer Using Simplified Radiological Criteria
Conclusions:
The novel criteria were accurate predictors of R status in PDAC patients undergoing upfront resection. After neoadjuvant treatment, likelihood of positive resection margins is approximately halved, and only perivascular SMA stranding remained a predictive factor. (Source: Annals of Surgery)
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Features Source Type: research
Defining Critical Portions of Surgery
No abstract available (Source: Annals of Surgery)
Source: Annals of Surgery - July 15, 2022 Category: Surgery Tags: Features Source Type: research
