Invited commentary

The key findings were that adding clopidogrel to regular aspirin therapy ≤48 hours of carotid endarterectomy (CEA) was associated with significant reductions in postoperative stroke, at the expense of increased bleeding complications.1 The latter will, inevitably, reinforce certain prejudices regarding dual-antiplatelet therapy (DAPT), even though the rate of bleeding complications was only 1.2% (DAPT) vs 0.7% (monotherapy). However, before uncritically disregarding any role for DAPT, it is worth considering why this debate is so important.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Clinical research study Source Type: research