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Condition: Asthma
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Total 773 results found since Jan 2013.
Circular RNA from phosphodiesterase 4D can attenuate chondrocyte apoptosis and matrix degradation under OA milieu induced by IL-1 β via circPDE4D/miR-4306/SOX9 cascade
CONCLUSION: CircPDE4D and miR-4306 were important regulators in regulating IL-1β-induced HNC apoptosis and matrix degradation via regulating the key transcription factor SOX9, suggesting a novel circPDE4D/miR-4306/SOX9 ceRNA pathway in OA-related chondrocyte dysfunction.PMID:35549803 | DOI:10.1080/08923973.2022.2077215
Source: Immunopharmacology and Immunotoxicology - May 13, 2022 Category: Allergy & Immunology Authors: Lixia Gao Xiaoyun Wang Jian Xiong Yan Ma Source Type: research
Syndemic Pandemic in Portugal: Social Inequality in Risk Factors Associated With COVID-19 Mortality
CONCLUSION: In 2019, we observed socioeconomic inequalities of high magnitude for the eight diseases with demonstrated link to COVID-19 mortality.PMID:35533082 | DOI:10.20344/amp.16031
Source: Acta Medica Portuguesa - May 9, 2022 Category: General Medicine Authors: Julian Perelman Source Type: research
Treatment of a 4-year-old boy with mepolizumab for Lymphocytic Hypereosinophilic Syndrome
A previously healthy 4-year-old boy presented to the emergency room with two days of headache, unsteady gait, and left hemiparesis. Emergent head CT revealed a right sided hypodensity concerning for ischemic stroke. Follow up MRI/MRA revealed multiple acute ischemic foci in the right MCA and PCA watershed territories, chronic appearing ischemic foci bilaterally, and bilateral carotid artery narrowing concerning for medium or large vessel vasculitis. Cardiac, hypercoagulability, and rheumatologic workup were unrevealing.
Source: Annals of Allergy, Asthma and Immunology - May 7, 2022 Category: Allergy & Immunology Authors: Jason A. Cascio, Madalyn Walsh, Kelly Hoenig, Benjamin Davis Tags: Letters Source Type: research
Risk of Chronic Conditions Found Higher Among Certain Groups With Depression, Anxiety
Women aged 20 to 60 with depression or anxiety were more likely to develop multiple chronic conditions over time compared with similarly aged women without depression or anxiety, according to areport published this week in JAMA Network Open. Women with comorbid anxiety and depression had an even greater risk of developing chronic conditions.Similarly, men with depression and/or anxiety at age 20 were more likely than those without depression or anxiety to develop chronic conditions.“Our findings support the need for managing comorbid depression and anxiety, which may help lower the risk of premature mortality associated ...
Source: Psychiatr News - May 5, 2022 Category: Psychiatry Tags: anxiety asthma cancer chronic conditions coronary artery disease depression diabetes hypertension JAMA Network Open men risk stroke women Source Type: research
Periodontitis Is Associated With Heart Failure: A Population-Based Study (NHANES III)
Conclusion: According to data from this nationally representative sample from the United States, periodontitis is associated with an increased risk of heart failure.
Source: Frontiers in Physiology - April 20, 2022 Category: Physiology Source Type: research
Allergies and the Heart; Tai Chi After Stroke; Viagra for Congenital Heart Disease?
(MedPage Today) -- Study finds that people with allergies and asthma were more likely to have high blood pressure and coronary heart disease, the American College of Cardiology announced.
The American Heart Association reviews the cardiovascular...
Source: MedPage Today Cardiovascular - April 12, 2022 Category: Cardiology Source Type: news
Prevalence and associated relating factors in patients with hereditary retinal dystrophy: a nationwide population-based study in Taiwan
CONCLUSIONS: 74% of the diagnosed HRD are retinitis pigmentosa. Population-based data suggested an increased incidence of cataract in younger patients, whereas older HRD patients are more susceptible to develop CME. Further work is needed to elucidate the mechanism between these ophthalmological disorders and HRD.PMID:35396285 | DOI:10.1136/bmjopen-2021-054111
Source: Cancer Control - April 9, 2022 Category: Cancer & Oncology Authors: Peng Yeong Woon Jia-Ying Chien Jen-Hung Wang Yu-Yau Chou Mei-Chen Lin Shun-Ping Huang Source Type: research
Oral tolerance: an updated review
Immunol Lett. 2022 Apr 5:S0165-2478(22)00041-4. doi: 10.1016/j.imlet.2022.03.007. Online ahead of print.ABSTRACTOral tolerance (OT) has classically been defined as the specific suppression of cellular and/or humoral immune responses to an antigen by prior administration of the antigen through the oral route. Multiple mechanisms have been proposed to explain the induction of OT including T cell clonal depletion and anergy when high doses of antigens are fed, and regulatory T (Treg) cell generation following oral administration of low and repeated doses of antigens. Oral antigen administration suppresses the immune response ...
Source: Immunology Letters - April 8, 2022 Category: Allergy & Immunology Authors: Rafael M Rezende Howard L Weiner Source Type: research
Influence of Renin-Angiotensin System Inhibitors on Postoperative Delirium in Patients With Pulmonary Arterial Hypertension: A Secondary Analysis of a Retrospective Cohort Study
ConclusionPreoperative use of ACEIs/ARBs in patients with PAH reduces the risk of POD. ACEIs/ARBs may be more recommended for patients with PAH in the future.
Source: Frontiers in Psychiatry - April 8, 2022 Category: Psychiatry Source Type: research
