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Condition: Arthritis
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Total 18 results found since Jan 2013.

Recurrent Embolic Strokes Associated with Vertical Atlantoaxial Subluxation in a Patient with Rheumatoid Arthritis: A Case Report and Review of Literature
We report a 78-year-old woman with rheumatoid arthritis who developed recurrent embolic cerebellar strokes associated with vertical atlantoaxial subluxation (AAS). On contrast angiography, the bilateral vertebral arteries (VAs) were occluded between the C1 and C2 levels, and the distal parts of bilateral VA were supplied by the collateral circulations. Dynamic cerebral angiography and carotid duplex ultrasonography showed that blood flow was substantially decreased in the left VA and left posterior inferior cerebellar artery on cervical anteflexion. It is suggested that vertical AAS reduced the blood flow of collateral cir...
Source: Journal of Stroke and Cerebrovascular Diseases - August 5, 2013 Category: Neurology Authors: Takuma Kuroki, Yuji Ueno, Ikuko Takeda, Taiki Kambe, Kenya Nishioka, Hideki Shimura, Masanori Itoh, Nobutaka Hattori, Takao Urabe Tags: Case Reports Source Type: research

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Healing through music
The last time I had a mammogram, I got a big surprise — and it was a good one. A string quartet was playing just outside the doors of the breast imaging center, and my thoughts immediately shifted from “What are they going to find on the mammogram?” to “Is that Schubert, or Beethoven?” By the time my name was called, I had almost forgotten why I was there. The unexpected concert was the work of Holly Chartrand and Lorrie Kubicek, music therapists and co-coordinators of the Environmental Music Program at Massachusetts General Hospital. But bringing music to hospital corridors is just a sideline for music therapist...
Source: New Harvard Health Information - November 5, 2015 Category: Consumer Health News Authors: Beverly Merz Tags: Behavioral Health Mental Health Pain Management Surgery Source Type: news

Rheumatoid Arthritis–Induced Lateral Atlantoaxial Subluxation With Multiple Vertebrobasilar Infarctions
Conclusion. In patients with RA, the potential risk of AAS should be recognized. Lateral AAS in particular may induce cerebral ischemia by positional VA occlusion in advanced stages of the disease. Level of Evidence: N/A
Source: Spine - January 31, 2015 Category: Orthopaedics Tags: Case Report Source Type: research

Duplex Ultrasonography-Detected Positional Vertebral Artery Occlusion in Upper Cervical Rheumatoid Arthritis
Study Design. Prospective imaging study. Objective. To clarify the frequency of positional vertebral artery (VA) occlusion using duplex ultrasonography in patients with rheumatoid arthritis (RA). Summary of Background Data. Some patients with upper cervical RA develop thromboembolic stroke related to positional and transient VA occlusions; however, whether RA patients have positional VA occlusion without neurological symptoms is unclear. Methods. Outpatients with RA were enrolled. Clinical data were collected, and radiograph examinations were performed to measure the anterior atlantodental interval (AADI), the posterior at...
Source: Spine - December 21, 2015 Category: Orthopaedics Tags: Cervical Spine Source Type: research

Not Just Acid Reflux: The Need to Think Worst First
Discussion Heart disease is the leading cause of death in the United States.1 This year, 720,000 Americans will have a new coronary event—defined as first hospitalized myocardial infarction (MI) or coronary heart disease death—and around 335,000 will have a recurrent event. Approximately 35% of people who experience a coronary event in a given year and around 14% of patients who have an acute coronary syndrome will die from it.1 Roughly 60% of patients with an acute coronary syndrome are transported to the emergency department via ambulance.2–4. Up to one-third of patients experiencing an MI may not complain of chest...
Source: JEMS Special Topics - January 13, 2019 Category: Emergency Medicine Authors: Stephen Sanko, MD, FACEP Tags: Exclusive Articles Cardiac & Resuscitation Source Type: news

Multimodal Optical Diagnostics of the Microhaemodynamics in Upper and Lower Limbs
Conclusion The use of optical non-invasive diagnostic methods has a great potential for the detection of concomitant microcirculation disorders in patients with rheumatic diseases and diabetes. In this review, it was shown that the use of laser Doppler flowmetry, optical tissue oximetry and fluorescence spectroscopy together or separately may have important diagnostic value for the detection of violations, assessment of their severity, as well as for the analysis of the effectiveness of the therapy. The joint application of the considered technologies with the methods of machine learning (discriminant analysis) can be use...
Source: Frontiers in Physiology - April 15, 2019 Category: Physiology Source Type: research

Biologics may prevent cardiovascular events in rheumatoid arthritis by inhibiting coronary plaque formation and stabilizing high ‐risk lesions
ConclusionIn rheumatoid arthritis, bDMARD use associated with reduced CVD risk, protective calcification of non ‐calcified lesions and lower likelihood of new plaque formation in patients with early atherosclerosis.
Source: Arthritis and Rheumatology - April 20, 2020 Category: Rheumatology Authors: George A Karpouzas, Sarah R Ormseth, Elizabeth Hernandez, Matthew J Budoff Tags: FULL LENGTH Source Type: research

Biologics May Prevent Cardiovascular Events in Rheumatoid Arthritis by Inhibiting Coronary Plaque Formation and Stabilizing High ‐Risk Lesions
ConclusionOur findings indicate that in RA, biologic DMARD use is associated with reduced CVD risk, protective calcification of noncalcified lesions, and lower likelihood of new plaque formation in patients with early atherosclerosis.
Source: Arthritis and Rheumatology - August 6, 2020 Category: Rheumatology Authors: George A. Karpouzas, Sarah R. Ormseth, Elizabeth Hernandez, Matthew J. Budoff Tags: Original Article Source Type: research

Trans ‐ventricular catheter device‐based closure of postmyocardial infarction ventricular septal defect following coronary artery bypass grafting: A staged hybrid approach
AbstractA 66 ‐year‐old woman with a history of hypertension, ischemic stroke, and rheumatoid arthritis presented to the hospital with severe angina pectoris and dyspnea and was diagnosed with myocardial infarction (MI). Coronary angiography revealed multisystem coronary artery occlusive disease. Due to refra ctory myocardial ischemia/evolving MI, emergency coronary artery bypass grafting (CABG) was undertaken. Intraoperative transesophageal echocardiography additionally revealed an apical muscular ventricular septal defect (VSD). Concomitant VSD repair was deferred due to the absence of surface evidence of transmural M...
Source: Journal of Cardiac Surgery - January 27, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Pranav Loyalka, Faisal H. Cheema, Shakeel Thakurdas, Keshava Rajagopal, Abdul Hannan Chaugle Tags: CASE REPORT Source Type: research

Serum cholesterol loading capacity on macrophages is linked to coronary atherosclerosis and cardiovascular event risk in rheumatoid arthritis
CONCLUSION: CLC was linked to long-term cardiovascular event risk in RA and associated with high-risk low attenuation and obstructive coronary plaque presence and burden in bDMARD non-users. Its prospective validation as a predictive biomarker may be, therefore, warranted.PMID:36113961 | DOI:10.1136/rmdopen-2022-002411
Source: Atherosclerosis - September 16, 2022 Category: Cardiology Authors: George Athanasios Karpouzas Bianca Papotti Sarah Ormseth Marcella Palumbo Elizabeth Hernandez Maria Pia Adorni Francesca Zimetti Matthew Budoff Nicoletta Ronda Source Type: research

ATP-binding cassette G1 membrane transporter-mediated cholesterol efflux capacity influences coronary atherosclerosis and cardiovascular risk in Rheumatoid Arthritis
CONCLUSION: ABCG1-CEC inversely associated with plaque burden and vulnerability, and plaque progression conditionally on cumulative inflammation and corticosteroid dose. ABCG1-CEC inversely associated with events specifically in patients with noncalcified plaques, lower inflammation and in prednisone users.PMID:36996698 | DOI:10.1016/j.jaut.2023.103029
Source: Journal of Autoimmunity - March 30, 2023 Category: Allergy & Immunology Authors: George A Karpouzas Bianca Papotti Sarah R Ormseth Marcella Palumbo Elizabeth Hernandez Maria Pia Adorni Francesca Zimetti Matthew J Budoff Nicoletta Ronda Source Type: research