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Condition: Rheumatoid Arthritis

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Total 493 results found since Jan 2013.

Improved Incidence of Cardiovascular Disease in Patients with Incident Rheumatoid Arthritis in the 2000s: a Population-Based Cohort Study
CONCLUSION: Incidence of major CVD events in RA has declined in recent decades. The gap in CVD occurrence between RA patients and the general population is closing. Mortality after CVD events in RA may be improving.PMID:33589553 | DOI:10.3899/jrheum.200842
Source: J Rheumatol - February 16, 2021 Category: Rheumatology Authors: Elena Myasoedova John M Davis Veronique L Roger Sara J Achenbach Cynthia S Crowson Source Type: research

The increased risk of atrial fibrillation in inflammatory arthritis: a systematic review and meta-analysis of cohort studies.
Conclusion: Patients with inflammatory arthritis have increased risk of AF, probably due to the underlying chronic inflammation. Although various confounders have been adjusted like medications use and comorbidities, the risk of AF is still significantly increased in inflammatory arthritis patients. Abbreviations: AF: Atrial fibrillation; AS: Ankylosing spondylitis; CI: Confidence interval; HR: Hazard ratio; NOS: Newcastle-Ottawa scale; NSAIDs: Non-steroid anti-inflammatory drugs; PsA: Psoriatic arthritis; RA: Rheumatoid arthritis; SpA: Spondyloarthritis; TNFi: Tumor necrosis factors inhibitor; uSpA: Undifferentiated spond...
Source: Immunological Investigations - February 12, 2021 Category: Allergy & Immunology Tags: Immunol Invest Source Type: research

Trans ‐ventricular catheter device‐based closure of postmyocardial infarction ventricular septal defect following coronary artery bypass grafting: A staged hybrid approach
AbstractA 66 ‐year‐old woman with a history of hypertension, ischemic stroke, and rheumatoid arthritis presented to the hospital with severe angina pectoris and dyspnea and was diagnosed with myocardial infarction (MI). Coronary angiography revealed multisystem coronary artery occlusive disease. Due to refra ctory myocardial ischemia/evolving MI, emergency coronary artery bypass grafting (CABG) was undertaken. Intraoperative transesophageal echocardiography additionally revealed an apical muscular ventricular septal defect (VSD). Concomitant VSD repair was deferred due to the absence of surface evidence of transmural M...
Source: Journal of Cardiac Surgery - January 27, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Pranav Loyalka, Faisal H. Cheema, Shakeel Thakurdas, Keshava Rajagopal, Abdul Hannan Chaugle Tags: CASE REPORT Source Type: research

Association Between Chronic Inflammatory Diseases and Stroke-Associated Pneumonia – An Epidemiological Study
This study assessed the relationship between chronic inflammatory diseases and stroke-associated pneumonia (SAP).
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2021 Category: Neurology Authors: Layne Dylla, Paco S. Herson, Sharon N. Poisson, John D. Rice, Adit A. Ginde Source Type: research

Temporal trends from 2005 to 2018 in deaths and cardiovascular events in subjects with newly diagnosed rheumatoid arthritis
AbstractAlthough rheumatoid arthritis (RA) is associated with an increased risk of death and cardiovascular (CV) disease, the excess of these risks is expected to have diminished over time, in more recent incident cohorts with RA. We analysed the risk of all-cause death, stroke, and myocardial infarction as primary outcomes and all CV events as secondary outcomes in RA subjects compared to the general population, from 2005 to 2018. The risk outcomes were also evaluated in relation to the time since RA diagnosis. We conducted a cohort study using linkable administrative healthcare databases of the Lombardy Region, Northern ...
Source: Internal and Emergency Medicine - January 2, 2021 Category: Emergency Medicine Source Type: research

Impact of comorbid conditions on health care expenditure and work-related outcomes in patients with rheumatoid arthritis.
CONCLUSION: Comorbid conditions in RA patients were associated with higher annual health care expenditure, lower likelihood of employment, higher rates of absenteeism and lower income. Despite its low prevalence, heart failure was associated with the highest incremental health care expenditure and the lowest likelihood of being employed compared to other common comorbid conditions. PMID: 33323533 [PubMed - as supplied by publisher]
Source: J Rheumatol - December 15, 2020 Category: Rheumatology Authors: Vu M, Carvalho N, Clarke PM, Buchbinder R, Tran-Duy A Tags: J Rheumatol Source Type: research

Systemic sclerosis and risk of cardiovascular disease: A PRISMA-compliant systemic review and meta-analysis of cohort studies
Conclusion: This meta-analysis revealed that SSc was associated with an increased risk of CVD. Clinicians who manage patients with SSc should be aware of the increased cardiovascular burden and undertake preventive measures.
Source: Medicine - November 20, 2020 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Benefits of Methotrexate Use on Cardiovascular Disease Risk among Rheumatoid Arthritis Patients Initiating Biologic Disease-Modifying Antirheumatic Drugs.
CONCLUSION: Among RA patients receiving biologics, concomitant methotrexate use was associated with a 24% lower risk for CVD events. PMID: 33060309 [PubMed - as supplied by publisher]
Source: J Rheumatol - October 15, 2020 Category: Rheumatology Authors: Xie F, Chen L, Yun H, Levitan EB, Curtis JR Tags: J Rheumatol Source Type: research

Cardiovascular risk and mortality in rheumatoid arthritis compared with diabetes mellitus and the general population
ConclusionThis study demonstrates that RA is associated with an increased risk of HF, MI, stroke and coronary revascularization than found in the GP but without reaching the risk levels observed in DM patients.
Source: Rheumatology - September 27, 2020 Category: Rheumatology Source Type: research

Interleukin-17 and ischemic stroke.
Abstract Interleukin-17 (IL-17) is a cytokine family that includes 6 members, IL-17A through IL-17F, most of them are reported to have pro-inflammatory role. Through binding to their receptors (IL-17Rs), IL-17 activates the intracellular signaling pathways to play an important role in autoimmune diseases, including rheumatoid arthritis (RA) and multiple sclerosis (MS). Ischemic stroke is a complex pathophysiological process mainly caused by regional cerebral ischemia. Inflammatory factors contribute to the physiological process of stroke that leads to poor prognosis. IL-17 plays a crucial role in promoting inflamm...
Source: Immunology - September 15, 2020 Category: Allergy & Immunology Authors: Zhang Q, Liao Y, Liu Z, Dai Y, Li Y, Li Y, Tang Y Tags: Immunology Source Type: research

Cross-diagnostic scale-banking using Rasch analysis: Developing a common reference metric for generic and health condition-specific scales in people with rheumatoid arthritis and stroke.
CONCLUSION: This study provides a transformation table to enable direct comparisons among instruments measuring physical functioning commonly used in rheumatoid arthritis (HAQ) and stroke (FIMTM motor scale), as well as in people with disability in general (WHODAS 2.0). PMID: 32909047 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - September 12, 2020 Category: Rehabilitation Tags: J Rehabil Med Source Type: research

Cardiovascular events and change in cholesterol levels in patients with rheumatoid arthritis treated with tocilizumab: data from the REGATE Registry.
CONCLUSIONS: In current practice, cardiovascular events occurring under TCZ treatment is in the range of what is expected in RA patients despite a global increase in cholesterol levels. PMID: 32896267 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - September 12, 2020 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research