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Condition: Rheumatoid Arthritis
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Total 493 results found since Jan 2013.
A Population-Based Cohort Study on Chronic Comorbidity Risk Factors for Adverse Dengue Outcomes
Am J Trop Med Hyg. 2021 Sep 27:tpmd210716. doi: 10.4269/ajtmh.21-0716. Online ahead of print.ABSTRACTThe global burden of dengue is increasing against a background of rising global prevalence of chronic noncommunicable diseases (NCDs) and an epidemiological shift of dengue toward older age groups. The contribution of NCDs toward risk for adverse clinical and healthcare utilization outcomes was assessed in a national linked-database study. About 51,433 adult dengue cases between 2014 and 2015 were assessed for outpatient and inpatient claims data in Taiwan's National Health Insurance Research Database for the 30 days after ...
Source: Am J Trop Med Hyg - September 28, 2021 Category: Infectious Diseases Authors: Chia-En Lien Yiing-Jenq Chou Yi-Jung Shen Theodore Tsai Nicole Huang Source Type: research
Contrast agents for photoacoustic imaging: a review of stem cell tracking
Stem Cell Res Ther. 2021 Sep 25;12(1):511. doi: 10.1186/s13287-021-02576-3.ABSTRACTWith the advent of stem cell therapy for spinal cord injuries, stroke, burns, macular degeneration, heart diseases, diabetes, rheumatoid arthritis and osteoarthritis; the need to track the survival, migration pathways, spatial destination and differentiation of transplanted stem cells in a clinical setting has gained increased relevance. Indeed, getting regulatory approval to use these therapies in the clinic depends on biodistribution studies. Although optoacoustic imaging (OAI) or photoacoustic imaging can detect functional information of ...
Source: Cell Research - September 26, 2021 Category: Cytology Authors: Soorya James Kai Neuhaus Mary Murphy Martin Leahy Source Type: research
Synthetically-tailored and nature-derived dual COX-2/5-LOX inhibitors: Structural aspects and SAR
Eur J Med Chem. 2021 Aug 27;225:113804. doi: 10.1016/j.ejmech.2021.113804. Online ahead of print.ABSTRACTInflammation is a most complex pathological process that gives birth to different diseases. Different inflammatory mediators are released during an inflammation responsible for acute pain and chronic inflammatory diseases like cancer, asthma, rheumatoid arthritis, osteoarthritis, neurodegenerative diseases, metabolic and cardiovascular disorders. The arachidonic acid pathway, which results in the production of inflammatory mediators, provides several targets for anti-inflammatory intervention. The most popularly used me...
Source: European Journal of Medicinal Chemistry - September 3, 2021 Category: Chemistry Authors: Minakshi A Meshram Utkarsha O Bhise Priyanka N Makhal Venkata Rao Kaki Source Type: research
Cardiovascular risk and mortality in rheumatoid arthritis compared with diabetes mellitus and the general population
Dear Editor, We read with great interest the work of L øgstrupet al. [1] studying cardiovascular risk and mortality in RA compared with diabetes mellitus (DM) and the general population. In their work, the authors longitudinally followed patients with RA and DM. They highlighted that RA is associated with an increased risk of heart failure, myocardial infarction (MI), stroke and coronary revascularization than is found in the general population, but without reaching the risk levels observed in DM patients. They pointed out that patients with incident RA have the same 10 year risk of MI compared with DM patients. Howeve...
Source: Rheumatology - August 13, 2021 Category: Rheumatology Source Type: research
Risk of thromboembolic events and associated risk factors, including treatments, in patients with immune-mediated diseases
This study assessed the association between thromboembolic events (TEs) and immune-mediated diseases (IMDs) and characterized the risk profile of TEs among patients with IMDs.METHODS: An administrative claims database (2014-2018) was used to identify adults with ≥2 diagnoses on different dates for ≥1 IMD (IMD cohort; ankylosing spondylitis, atopic dermatitis, inflammatory bowel disease, multiple sclerosis, psoriasis, psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus); patients without an IMD diagnosis were assigned to the non-IMD cohort. Patients in the IMD cohort were matched 1:1 to patients ...
Source: Clinical Therapeutics - July 9, 2021 Category: Drugs & Pharmacology Authors: Juliana Setyawan Fan Mu Andres Yarur Miriam L Zichlin Hongbo Yang Catherine Fernan Emma Billmyer Nathaniel Downes Nassir Azimi Vibeke Strand Source Type: research
Development and validation of a nomogram for predicting stroke risk in rheumatoid arthritis patients
In conclusion, the nomogram can be used for individualized preoperative prediction of stroke risk in RA patients.PMID:34081620 | DOI:10.18632/aging.203071
Source: Aging - June 3, 2021 Category: Biomedical Science Authors: Fangran Xin Lingyu Fu Bowen Yang Haina Liu Tingting Wei Cunlu Zou Bingqing Bai Source Type: research
Clinical characteristics, triggering etiologies, and response of plasmapheresis in thrombotic microangiopathy in Taiwan
This study indicated the spectrum of underlying causes, extra-renal characteristics, and the response to plasmapheresis of patients with TMA in Taiwan. Of note, the poor clinical outcomes of plasmapheresis in patients with TMA might highlight the masked underlying etiology or worse disease condition that should be noticed.
Source: Medicine - May 21, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Association between ischemic stroke and seropositive rheumatoid arthritis in Korea: A nationwide longitudinal cohort study
by Dong Hyun Lee, Seung Hun Sheen, Dong-Geun Lee, Jae-Won Jang, Dong Chan Lee, Seung-Ho Shin, In-bo Han, Je Beom Hong, Hakyung Kim, Seil Sohn
The purpose of this longitudinal follow-up study was to investigate the risk of ischemic stroke nationwide in patients with seropositive rheumatoid arthritis (RA) and controls who were matched in age and sex. Patient data were collected from the National Health Insurance Service (NHIS) Health Scre ening (HEALS) cohort. Using the International Classification of Diseases code M05 (seropositive RA), with a prescription of any disease-modifying anti-rheumatic drug (DMARD), RA was identi...
Source: PLoS One - May 17, 2021 Category: Biomedical Science Authors: Dong Hyun Lee Source Type: research
Sinomenine activation of Nrf2 signaling prevents inflammation and cerebral injury in a mouse model of ischemic stroke
In conclusion, the findings of the present study identified a novel pathway through which SINO may exert its anti-inflammatory and cerebral protective functions, and provided a molecular basis for the potential applications of SINO in the treatment of cerebral inflammatory disorders.PMID:33968178 | PMC:PMC8097210 | DOI:10.3892/etm.2021.10079
Source: Experimental and Therapeutic Medicine - May 10, 2021 Category: General Medicine Authors: Fangfang Bi Yiyong Zhang Wenbo Liu Keliang Xie Source Type: research
Systemic inflammatory response index as an independent risk factor for ischemic stroke in patients with rheumatoid arthritis: a retrospective study based on propensity score matching
ConclusionSIRI was independently associated with the occurrence of ischemic stroke in patients with RA. Thus, RA patients with elevated SIRI should be closely monitored.Key points•RA patients with IS had fewer traditional risk factors such as hypertension and diabetes, while inflammatory indicators were significantly increased.•The SIRI have drawn attention in recent years as novel non-specific inflammatory markers. However, only a few studies have been conducted to investigate their value in RA.•This study completes the gaps in the research on the relationship between SIRI and the risk of IS occurrence in RA patients.
Source: Clinical Rheumatology - May 9, 2021 Category: Rheumatology Source Type: research
