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Condition: Dementia

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Total 4555 results found since Jan 2013.

Development and validation of a dementia risk score in the UK Biobank and Whitehall II cohorts
Background Current dementia risk scores have had limited success in consistently identifying at-risk individuals across different ages and geographical locations. Objective We aimed to develop and validate a novel dementia risk score for a midlife UK population, using two cohorts: the UK Biobank, and UK Whitehall II study. Methods We divided the UK Biobank cohort into a training (n=176 611, 80%) and test sample (n=44 151, 20%) and used the Whitehall II cohort (n=2934) for external validation. We used the Cox LASSO regression to select the strongest predictors of incident dementia from 28 candidate predictors and then dev...
Source: Evidence-Based Mental Health - August 21, 2023 Category: Psychiatry & Psychology Authors: Anatürk, M., Patel, R., Ebmeier, K. P., Georgiopoulos, G., Newby, D., Topiwala, A., de Lange, A.-M. G., Cole, J. H., Jansen, M. G., Singh-Manoux, A., Kivimäki, M., Suri, S. Tags: Open access, Press releases Old age psychiatry Source Type: research

Risk factors for dementia in older intensive care unit (ICU) survivors
DISCUSSION: Future studies will need to examine whether interventions targeting post-ICU stroke and depression can lower dementia incidence in ICU survivors.HIGHLIGHTS: Risk factors for post-intensive care unit (ICU) dementia were distinct from those of Alzheimer's disease. Cardiovascular risk factors were not associated with dementia in older ICU survivors. Post-ICU stroke was associated with a higher risk of dementia in older ICU survivors. Post-ICU depression was associated with a higher risk of dementia in older ICU survivors.PMID:37589315 | DOI:10.1002/alz.13423
Source: The Journal of Alzheimers Association - August 17, 2023 Category: Psychiatry Authors: Sophia Wang Anthony J Perkins Rosalyn Chi Brandon A Yates Sikandar H Khan Sujuan Gao Malaz Boustani Babar A Khan Source Type: research

Atrial fibrillation catheter ablation associated silent cerebral emboli: A narrative review
AbstractThe incidence of silent cerebral emboli (SCE) associated with atrial fibrillation catheter ablation (AFCA) is much higher than that of stroke/transient ischemic attack (TIA). Interventional electrophysiologists have been increasingly alerted to asymptomatic cerebral infarction over the years. Plentiful studies revealed that diagnostic definitions, detection modalities, energy sources, ablation strategies, perioperative anticoagulation regimens, and patient-related factors were associated with the risk of AFCA-associated SCE. Studies related to non-interventional procedures found that SCE may prompt stroke, cognitiv...
Source: Pacing and Clinical Electrophysiology : PACE - August 15, 2023 Category: Cardiology Authors: Jingrui Zhang, Songnan Li, Caihua Sang, Changsheng Ma Tags: INVITED REVIEW Source Type: research

Dysphagia in Neurological Disorders
Semin Neurol DOI: 10.1055/s-0043-1771458Dysphagia is a common symptom in many neurologic disorders. Patients with oropharyngeal dysphagia present with difficulties when they start to swallow, often with coughing and choking; whereas patients with esophageal dysphagia describe the feeling that swallowed food stops in the chest. Chronic neurologic diseases such stroke, Parkinson's disease, or dementia often have dysphagia as a symptom, particularly oropharyngeal dysphagia, and the term “neurogenic dysphagia” is often used. A disruption of the sophisticated, integrated sensorimotor swallowing system is usually the main re...
Source: Seminars in Neurology - August 14, 2023 Category: Neurology Authors: El Halabi, Maan Arwani, Remy Parkman, Henry P. Tags: Review Article Source Type: research

The Polyherbal Functional Ingredient Containing Ginger, Chinese Date, and Wood Ear Mushroom Protects against Dementia following Metabolic Syndrome
This study was performed to test this hypothesis and to explore the underlying mechanism. Male Wistar rats weighing 180-220 g were induced metabolic syndrome (MetS) with a 16-week high-carbohydrate high-fat diet (HCHF) feeding. The rats with MetS characteristics were orally administered GCJ at various doses (GCJ100, GCJ200, and GCJ300 mg kg-1 BW) 21 days pre-induction and 21 days post-induction of reperfusion injury (I/R) at the right middle cerebral artery (MCAO). Memory was evaluated every 7 days during the study period. At the end of the study, neuron density, AChE activity, and the expressions of eNOS, BDNF, and pERK/E...
Source: Biomed Res - August 11, 2023 Category: Research Authors: Thuntiva Nakyam Jintanaporn Wattanathorn Wipawee Thukham-Mee Supaporn Muchimapura Source Type: research

Alzheimer's Behavioral and Psychiatric Burden in Saudi Arabia: Validation of the Saudi Version of the Neuropsychiatric Inventory
CONCLUSIONS: The SNPI is valid and reliable for assessing BPSD in Saudi AD patients. Longitudinal studies of BPSDs in Saudi specialized dementia clinics are needed.PMID:37561963 | DOI:10.1097/WAD.0000000000000563
Source: Alzheimer Disease and Associated Disorders - August 10, 2023 Category: Psychiatry Authors: Haythum O Tayeb Nadeem S Butt Roaa Khallaf Bassam Yahghmour Mohammed A Basheikh Sultan H Alamri Abrar O Baduwailan Faten Alzaben Haifa K Abdulghaffar Harold G Koenig Source Type: research

Dementia Prevalence and Risk Factors: Data From Rural Tanzania
CONCLUSIONS: The prevalence of dementia in this population is similar to a recent community-based rate in Tanzania and lower than a hospital-based rate in Senegal. This is the first time the association between visual impairment and dementia has been reported in SSA. Other associations are in keeping with previous literature.PMID:37561952 | DOI:10.1097/WAD.0000000000000564
Source: Alzheimer Disease and Associated Disorders - August 10, 2023 Category: Psychiatry Authors: Caitlin Roe Ssenku Safic Lwitiko Mwaipopo Catherine L Dotchin Joanna Klaptocz William Gray Marcyella Joseph Aimee Spector Sarah Urasa Richard W Walker Source Type: research

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