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Condition: Dementia

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Total 4555 results found since Jan 2013.

Malnutrition risk in hospitalized patients measured with Nutrition Risk Screening 2002 tool and its association with in-hospital mortality
CONCLUSIONS: AMR revealed that NRS-2002 is positive in approximately half of the hospitalized patients, which is associated with in-hospital mortality independent of the underlying diseases. NT is related to weight gain and increased serum albumin.PMID:37401318 | DOI:10.26355/eurrev_202306_32820
Source: European Review for Medical and Pharmacological Sciences - July 4, 2023 Category: Drugs & Pharmacology Authors: O K Bakkaloglu M Bektas B Ince S Amikishiyev Y B Tor M Alt ınkaynak Y Goksoy B Ozmen S Buyukdemir S N Erten T S Akpinar B Saka Source Type: research

Characterising heart rhythm abnormalities associated with Xp22.31 deletion
Conclusion Our data suggest AHRs are frequently associated with Xp22.31 deletion, and highlight subgroups of deletion carriers that may be prioritised for screening. Examining cardiac function further in deletion carriers, and in model systems lacking steroid sulfatase, may clarify AF pathophysiology.
Source: Journal of Medical Genetics - June 21, 2023 Category: Genetics & Stem Cells Authors: Wren, G., Baker, E., Underwood, J., Humby, T., Thompson, A., Kirov, G., Escott-Price, V., Davies, W. Tags: Open access Genotype-phenotype correlations Source Type: research

Edaravone Dexborneol Alleviates Neuroinflammation by Reducing Neuroglial Cell Proliferation and Suppresses Neuronal Apoptosis/Autophagy in Vascular Dementia Rats
In this study, we established the VD model of rats by bilateral carotid artery occlusion to explore the neuroprotective effect of EDB and its mechanism. Morris Water Maze test was applied to assess the cognitive function of rats. H&E and TUNEL staining were applied to observe the cellular structure of the hippocampus. Immunofluorescence labeling was used to observe the proliferation of astrocytes and microglia. ELISA was applied to examine the levels of TNF-α, IL-1β and IL-6, and RT-PCR was applied to examine their mRNA expression levels. Western blotting was applied to examine apoptosis-related proteins (Bax, Bcl-2,...
Source: Neurochemical Research - June 20, 2023 Category: Neuroscience Authors: Jiawei Zhang Yining Xiao Hongna Liu Lili Xu Xing Guo Yaran Gao Meixi Li Jing Xu Qianqian Qi Peiyuan Lv Source Type: research

Sex differences in cognitive impairment after focal ischemia in middle-aged rats and the effect of iv miR-20a-3p treatment
Neurobiol Aging. 2023 May 5;129:168-177. doi: 10.1016/j.neurobiolaging.2023.05.001. Online ahead of print.ABSTRACTStroke is a major cause of death and disability worldwide and is also a leading cause of vascular dementia and Alzheimer's disease, with older women experiencing accelerated decline. Our previous studies show that intravenous (iv) injections of miR-20a-3p, a small noncoding RNA (miRNA) delivered after stroke improves acute stroke outcomes in middle-aged male and female rats. The present study tested whether mir-20a-3p treatment would also ameliorate stroke-induced cognitive decline in the chronic phase. Acyclic...
Source: Neurobiology of Aging - June 19, 2023 Category: Geriatrics Authors: Dayalan Sampath Taylor E Branyan Kylee G Markowsky Rithvik Gunda Nadia Samiya Andre Obenaus Farida Sohrabji Source Type: research