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Total 4555 results found since Jan 2013.

Cerebral ischemic injury after transcatheter aortic valve replacement in patients with pure aortic regurgitation
J Zhejiang Univ Sci B. 2023 Jun 15;24(6):530-538. doi: 10.1631/jzus.B2200444.ABSTRACTConsidering the surgical risk stratification for patients with severe calcific aortic stenosis (AS), transcatheter aortic valve replacement (TAVR) is a reliable alternative to surgical aortic valve replacement (SAVR) (Fan et al., 2020, 2021; Lee et al., 2021). Despite the favorable clinical benefits of TAVR, stroke remains a dreaded perioperative complication (Auffret et al., 2016; Kapadia et al., 2016; Kleiman et al., 2016; Huded et al., 2019). Ischemic overt stroke, identified in 1.4% to 4.3% of patients in TAVR clinical practice, has be...
Source: J Zhejiang Univ Sci ... - June 13, 2023 Category: Science Authors: Xianbao Liu Hanyi Dai Jiaqi Fan Dao Zhou Gangjie Zhu Abuduwufuer Yidilisi Jun Chen Yeming Xu Lihan Wang Jian'an Wang Source Type: research

Cerebral Small Vessel Disease burden: An independent biomarker for anomia treatment responsiveness in chronic stroke patients with aphasia
CONCLUSIONS: cSVD, a marker of brain reserve and a robust risk factor for post-stroke dementia, may be used as a biomarker for distinguishing patients that are more likely to respond to anomia therapy from those that are less likely to do so and for individualizing treatment parameters (e.g., targeting both linguistic and nonlinguistic cognition in severe cSVD).PMID:37290492 | DOI:10.1016/j.apmr.2023.05.008
Source: Health Physics - June 8, 2023 Category: Physics Authors: Maria Varkanitsa Claudia Pe ñaloza Andreas Charidimou Swathi Kiran Source Type: research

Inflammatory-associated proteomic predictors of cognitive outcome in subjects with ELVO treated by mechanical thrombectomy
Emergent Large Vessel Occlusion (ELVO) stroke causes devastating vascular events which can lead to significant cognitive decline and dementia. In the subset of ELVO subjects treated with mechanical thrombectom...
Source: BMC Neurology - June 6, 2023 Category: Neurology Authors: Benton Maglinger, Jordan P. Harp, Jacqueline A. Frank, Chintan Rupareliya, Christopher J. McLouth, Shivani Pahwa, Lila Sheikhi, David Dornbos III, Amanda L. Trout, Ann M. Stowe, Justin F. Fraser and Keith R. Pennypacker Tags: Research article Source Type: research

Risks of neurological and psychiatric sequelae 2 years after hospitalisation or intensive care admission with COVID-19 compared to admissions for other causes
Brain Behav Immun. 2023 May 30:S0889-1591(23)00132-0. doi: 10.1016/j.bbi.2023.05.014. Online ahead of print.ABSTRACTThe association between COVID-19 and subsequent neurological and psychiatric disorders is well established. However, two important questions remain unanswered. First, what are the risks in those admitted to intensive care unit (ICU) with COVID-19? Admission to ICU is itself associated with neurological and psychiatric sequelae and it is not clear whether COVID-19 further increases those risks or changes their profile. Second, what are the trajectories of neurological and psychiatric risks in patients admitted...
Source: Brain, Behavior, and Immunity - June 1, 2023 Category: Neurology Authors: Harriet Ley Zuzanna Skorniewska Paul J Harrison Maxime Taquet Source Type: research

A bibliometric analysis of cerebral microbleeds and cognitive impairment
CONCLUSION: This bibliometric analysis reveals a strong link between CMBs and cognitive impairment-related diseases and that specific brain networks were affected by CMBs. This provides further insights into the possible mechanisms and causes of CMBs and cognitive impairment. The direct and indirect damage (such as oxidative stress and neuroinflammation) to the brain caused by CMBs, destruction of the frontal-subcortical circuits, elevated Cystatin C levels, and iron deposition are involved in the occurrence and development of cognitive impairment. CMBs may be a potential marker for detecting, quantifying, and predicting c...
Source: Brain and Cognition - June 1, 2023 Category: Neurology Authors: Rui Yang Jia Li Yaya Qin Li Zhao Rong Liu Fanhui Yang Guohui Jiang Source Type: research

Gender heterogeneity in the influencing factors for cerebral microbleeds in acute ischemic stroke patients
CONCLUSION: There are gender differences in the influencing factors for CMBs in AIS patients. Age, old LIs, and blood glucose are independent risk or protective factors for comorbid CMBs in female AIS patients, although they are not associated with the risk of developing CMBs in male AIS patients.PMID:37259500 | DOI:10.1080/03007995.2023.2219581
Source: Current Medical Research and Opinion - June 1, 2023 Category: Research Authors: Xin Guo Yuan Xing Zhenjie Teng Zhiyuan Shen Xiaosu Guo Peiyuan Lv Shujuan Tian Source Type: research

Occupational therapy for persons with cognitive impairments
CONCLUSIONS: Based on this systematic overview, it can neither be proven nor excluded with certainty that occupational therapy for cognitive impairment is an effective therapy for adult patients with central nervous system injuries compared to no occupational therapy. There is a lack of randomised trials with sufficient sample size, well-defined interventions, and comparable concomitant therapies in the control groups, but there is also a lack of well-designed observational studies in routine care and health economic studies. The identified systematic reviews on patient and social aspects provide information on the needs o...
Source: GMS German Medical Science - June 1, 2023 Category: General Medicine Authors: Petra Schnell-Inderst Annette Conrads-Frank Igor Stojkov Cornelia Krenn Lisa-Maria Kofler Uwe Siebert Source Type: research

Risks of neurological and psychiatric sequelae 2 years after hospitalisation or intensive care admission with COVID-19 compared to admissions for other causes
Brain Behav Immun. 2023 May 30:S0889-1591(23)00132-0. doi: 10.1016/j.bbi.2023.05.014. Online ahead of print.ABSTRACTThe association between COVID-19 and subsequent neurological and psychiatric disorders is well established. However, two important questions remain unanswered. First, what are the risks in those admitted to intensive care unit (ICU) with COVID-19? Admission to ICU is itself associated with neurological and psychiatric sequelae and it is not clear whether COVID-19 further increases those risks or changes their profile. Second, what are the trajectories of neurological and psychiatric risks in patients admitted...
Source: Brain, Behavior, and Immunity - June 1, 2023 Category: Neurology Authors: Harriet Ley Zuzanna Skorniewska Paul J Harrison Maxime Taquet Source Type: research

Occupational therapy for persons with cognitive impairments
CONCLUSIONS: Based on this systematic overview, it can neither be proven nor excluded with certainty that occupational therapy for cognitive impairment is an effective therapy for adult patients with central nervous system injuries compared to no occupational therapy. There is a lack of randomised trials with sufficient sample size, well-defined interventions, and comparable concomitant therapies in the control groups, but there is also a lack of well-designed observational studies in routine care and health economic studies. The identified systematic reviews on patient and social aspects provide information on the needs o...
Source: GMS German Medical Science - June 1, 2023 Category: General Medicine Authors: Petra Schnell-Inderst Annette Conrads-Frank Igor Stojkov Cornelia Krenn Lisa-Maria Kofler Uwe Siebert Source Type: research

A bibliometric analysis of cerebral microbleeds and cognitive impairment
CONCLUSION: This bibliometric analysis reveals a strong link between CMBs and cognitive impairment-related diseases and that specific brain networks were affected by CMBs. This provides further insights into the possible mechanisms and causes of CMBs and cognitive impairment. The direct and indirect damage (such as oxidative stress and neuroinflammation) to the brain caused by CMBs, destruction of the frontal-subcortical circuits, elevated Cystatin C levels, and iron deposition are involved in the occurrence and development of cognitive impairment. CMBs may be a potential marker for detecting, quantifying, and predicting c...
Source: Brain and Cognition - June 1, 2023 Category: Neurology Authors: Rui Yang Jia Li Yaya Qin Li Zhao Rong Liu Fanhui Yang Guohui Jiang Source Type: research

Gender heterogeneity in the influencing factors for cerebral microbleeds in acute ischemic stroke patients
CONCLUSION: There are gender differences in the influencing factors for CMBs in AIS patients. Age, old LIs, and blood glucose are independent risk or protective factors for comorbid CMBs in female AIS patients, although they are not associated with the risk of developing CMBs in male AIS patients.PMID:37259500 | DOI:10.1080/03007995.2023.2219581
Source: Current Medical Research and Opinion - June 1, 2023 Category: Research Authors: Xin Guo Yuan Xing Zhenjie Teng Zhiyuan Shen Xiaosu Guo Peiyuan Lv Shujuan Tian Source Type: research