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Total 1829 results found since Jan 2013.

Coding and non-coding nucleotides': The future of stroke gene therapeutics
Genomics. 2021 Mar 4:S0888-7543(21)00084-7. doi: 10.1016/j.ygeno.2021.03.003. Online ahead of print.ABSTRACTStroke is the foremost cause of death ranked after heart disease and cancer. It is the fatal life-threatening event that requires immediate medical admissions to overcome following morbidity and mortality. The therapeutic advances in stroke therapy have been manipulated with diverse paths for last 5 years. Recent research and clinical trials have investigated a variety of anti-stroke agents including anti-coagulants, cerebro-protective agents, antiplatelet therapy, stem-cell therapy, and specified gene therapy. In re...
Source: Genomics - March 7, 2021 Category: Genetics & Stem Cells Authors: Vishal Chavda Kajal Madhwani Source Type: research

Comparison of Clinical Features, Immune-Inflammatory Markers, and Outcomes Between Patients with Acute In-Hospital and Out-of-Hospital Ischemic Stroke
CONCLUSION: Patients with IHIS had more complicated clinical features, higher levels of immune-inflammatory markers, and higher rates of mortality than patients with OHIS. The most significant predictor for mortality among those with OHIS was NIHSS score >10, and the predictors among patients with IHIS were NLR >5.5 and SII >2120.PMID:35177921 | PMC:PMC8843816 | DOI:10.2147/JIR.S342830
Source: Atherosclerosis - February 18, 2022 Category: Cardiology Authors: Pei-Ya Chen Guei-Chiuan Chen Cheng-Lun Hsiao Po-Jen Hsu Fu-Yi Yang Chih-Yang Liu Adam Tsou Wan-Ling Chang Hsiu-Hsun Liu Shinn-Kuang Lin Source Type: research

Predictive Value of the Systemic Immune Inflammation Index for Adverse Outcomes in Patients With Acute Ischemic Stroke
ConclusionThe systemic immune-inflammation index is associated with short-term adverse outcomes in patients with acute ischemic stroke, and the nomograms can predict the risk of adverse outcomes in patients with acute ischemic stroke.
Source: Frontiers in Neurology - March 18, 2022 Category: Neurology Source Type: research

Effect modification of age and hypertension on cancer and prevalence of self ‐reported stroke – A cross‐sectional study
The objective of this study was to examine the effect modification of age on the relationship between cancer and prevalence of self-reported stroke. We used cross-sectional data from the 2015 –2016 iteration of the Canadian Community Health Survey. A multivariable logistic regression model was used to assess the association between cancer and self-reported stroke. Covariates were assessed for effect modification using the maximum likelihood estimation method. We analyzed 86,809 subject s; the prevalence of self-reported stroke was 1.11%. The odds ratio for the association between cancer and self-reported stroke was 1.26 ...
Source: Cancer Medicine - April 21, 2023 Category: Cancer & Oncology Authors: Ronda Lun, Joseph R. Shaw, Danielle Carole Roy, Deborah Siegal, Tim Ramsay, Yue Chen, Dar Dowlatshahi Tags: BRIEF COMMUNICATION Source Type: research

Original Articles Low Socioeconomic Status and Psychological Distress as Synergistic Predictors of Mortality From Stroke and Coronary Heart Disease
Conclusions People in low socioeconomic circumstances are more vulnerable to the adverse effect of psychological distress. This pattern should be taken into account when evaluating the association between psychosocial variables and health outcomes.
Source: Psychosomatic Medicine - April 3, 2013 Category: Psychiatry & Psychology Authors: Lazzarino, A. I., Hamer, M., Stamatakis, E., Steptoe, A. Tags: Social Class, Stress and Coping, Coronary Artery Disease Original Articles Source Type: research

Application of Knowledge Discovery Process on the Prediction of Stroke
Stroke is a significant cause for cognitive disorders around the world. In developing countries, there is a shortage of data in regards to the public health extent of stroke [1]. Stroke is a growing illness and is the third prevalent cause for death after coronary heart disease and cancer in the world, particularly in older people. Stroke regularly caused increased morbidity, mortality and decreased life quality in the community [2].
Source: Computer Methods and Programs in Biomedicine - March 14, 2015 Category: Bioinformatics Authors: Cemil Colak, Esra Karaman, M. Gokhan Turtay Source Type: research

Stroke.
Authors: Abstract Essential facts According to the Stroke Association, approximately 152,000 people in the UK have a stroke each year and one in five are fatal. In 2010, stroke was the fourth largest cause of death after heart disease, cancer and respiratory disease. One in four strokes in the UK happen to people under the age of 65. PMID: 26036380 [PubMed - in process]
Source: Nursing Standard - June 3, 2015 Category: Nursing Tags: Nurs Stand Source Type: research

UK heart disease and stroke death rates now lower than cancer
Conclusion This valuable research informs on the burden of cardiovascular disease and associated mortality across European countries. It demonstrates that CVD is still the most common cause of death across Europe, but rates have been falling over the past 10 years. This fall means that in several European countries, including the UK, cancer rates now overtake CVD death rates in men. Generally, CVD disability and burden of disease seems to be greater in Eastern European countries. The WHO mortality data and population data are quite up-to-date and should be reliable, though as the researchers say, there was a lack of high ...
Source: NHS News Feed - August 15, 2016 Category: Consumer Health News Tags: Heart/lungs Cancer Neurology Source Type: news

A new era in stroke care gives larger treatment window and better outcomes
According to the American Heart/American Stroke Association, stroke affects nearly 800,000 people in the United States each year. It is the fifth leading cause of death, and the leading cause of long-term disability.  It’s also the leading cause of preventable disability. In China it is the leading cause of death surpassing both cancer and heart disease. Stroke occurs when a blood vessel carrying oxygen and nutrients to the brain is either blocked by a blood clot or plaque (ischemic stroke), or…
Source: bizjournals.com Health Care News Headlines - August 15, 2018 Category: Health Management Authors: Alexandria Foley Source Type: news

Edoxaban for the prevention of stroke in patients with atrial fibrillation.
Authors: Cervantes CE, Merino JL, Barrios V Abstract INTRODUCTION: Edoxaban is the last direct oral anticoagulant marketed for the prevention of stroke among patients with nonvalvular atrial fibrillation (AF). Areas covered: ENGAGE AF-TIMI 48 was the pivotal clinical trial that led to the approval of edoxaban 60 mg once daily. After the publication of this study, a great number of substudies and post hoc analyses have been published, together with some observational studies. The aim of this review was to update the current evidence about the use of edoxaban in AF patients. Expert commentary: In the ENGAGE AF-TIMI 4...
Source: Expert Review of Cardiovascular Therapy - March 24, 2019 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Change in Prescribing for  Secondary Prevention of Stroke and Coronary Heart Disease in Finnish Nursing Homes and Assisted Living Facilities
ConclusionsThe decline in cardiovascular medication use in residents with CHD and dementia suggests Finnish physicians are adopting a more conservative approach to the management of cardiovascular disease in the NH population.
Source: Drugs and Aging - April 4, 2019 Category: Geriatrics Source Type: research