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Total 1829 results found since Jan 2013.

Scan could detect those on brink of heart attack
Conclusion This is a valuable study which shows the promise of using PET-CT with radioactively labelled sodium fluoride (NaF) as a way of identifying fatty deposits in the heart arteries that could be at risk of rupturing and causing a heart attack. The results confirmed that the marker used in this study (NaF) was better than the chemical marker normally used in PET-CT scans (FDG). The technique has the principal value of being a non-invasive technique compared with coronary angiography, which is the standard method used to look at blockages in heart arteries. As it does not involve surgical intervention, this could ha...
Source: NHS News Feed - November 11, 2013 Category: Consumer Health News Tags: Heart/lungs Medical practice Source Type: news

Effects of Habitual Coffee Consumption on Cardiometabolic Disease, Cardiovascular Health, and All-cause Mortality: O'Keefe JH, Bhatti SK, Patil HR. J Am Coll Cardiol 2013;62:1043−51.
This study examines existing data regarding coffee consumption and its effect on health and all-cause mortality. Coffee consumption confers a benefit in the reduction of Type II diabetes mellitus (T2DM). There was significant reduction in a dose-dependent relationship of coffee consumption and reduction of T2DM. Caffeinated and noncaffeinated beverages confer the same benefit. The authors conclude that coffee's effect on serum lipids is a dose-dependent increase in serum total cholesterol and a nonsignificant increase in low-density lipoprotein concentrations in only boiled preparations of coffee, but not for filtered coff...
Source: The Journal of Emergency Medicine - April 24, 2014 Category: Emergency Medicine Authors: Java Tunson Tags: Abstracts Source Type: research

Cycling linked to prostate cancer, but not infertility
Conclusion This study has looked at the associations between the number of hours spent cycling a week and erectile dysfunction, infertility and prostate cancer in men over the age of 50 who cycle regularly. It found no association between the time spent cycling and erectile dysfunction or infertility, but did find a dose-response association with prostate cancer for men over the age of 50, with risk increasing as the time a week spent cycling increased. As the researchers point out, this type of study cannot prove causality (that increased cycling time leads to prostate cancer), only an association. Different study desig...
Source: NHS News Feed - July 9, 2014 Category: Consumer Health News Tags: Cancer Lifestyle/exercise Source Type: news

A critique of Women's Health Initiative Studies (2002-2006).
Authors: Clark JH Abstract The Women's Health Initiative Studies (WHI) were designed to examine the effects of estrogen and progestin (E+P; Prempro) and estrogen alone (Premarin) in post-menopausal women. The authors of the WHI studies and the National Heart Lung and Blood Institute (NHLBI) concluded that E+P treatment increased the risks of coronary heart disease, invasive breast cancer, stroke and venous thromboembolism. The following paper contains a reevaluation of these studies based on the graphic analysis of their tabulated data. In contrast to the conclusions reached by the WHI and the NHLBI, I conclude tha...
Source: Nuclear receptor signaling - November 12, 2014 Category: Molecular Biology Tags: Nucl Recept Signal Source Type: research

Title: Ritual Risk: Incense Use and Cardiovascular Mortality
This study is of particular significance given that cardiovascular disease is one of the most common chronic diseases in the population worldwide,” says Karin Yeatts, an epidemiologist at the University of North Carolina at Chapel Hill, who has studied indoor air quality in the Middle East. In contrast with outdoor air pollution, incense exposure may be easier for an individual to avoid, but Yeatts says education will be needed to help people understand the risks of these exposures, similar to educational campaigns about cigarette smoking. Limitations to the study include lack of information on the type of incense burned...
Source: EHP Research - December 1, 2014 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Cardiovascular Health Combustion Emissions December 2014 Household Air Pollution Indoor Air Quality International Environmental Health Particulate Matter (PM) Volatile Organic Compounds (VOCs) Source Type: research

Managing menopause.
Authors: Reid R, Abramson BL, Blake J, Desindes S, Dodin S, Johnston S, Rowe T, Sodhi N, Wilks P, Wolfman W, Menopause and Osteoporosis Working Group, Fortier M, Reid R, Abramson BL, Blake J, Desindes S, Dodin S, Graves L, Guthrie B, Khan A, Johnston S, Rowe T, Sodhi N, Wilks P, Wolfman W Abstract OBJECTIVE: To provide updated guidelines for health care providers on the management of menopause in asymptomatic healthy women as well as in women presenting with vasomotor or urogenital symptoms and on considerations related to cardiovascular disease, breast cancer, urogynaecology, and sexuality. OUTCOMES: Lifestyle...
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - December 2, 2014 Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research

Abstract B84: Increasing disparities in breast cancer mortality for young black women in the U.S. from 1979-2010
Conclusions: Though mortality rates have declined over the past 30 years for women under 50, significant disparities in the two leading causes of death, cancer and CVD, remain. The persistence of disparities across diseases highlights the need to focus on improving health outcomes broadly, in addition to disease centered approaches, in order to prevent premature deaths among young women. The breast cancer mortality rate was two times greater among black women younger than 50 compared to white women, indicating a more profound disparity in younger women than older women. Furthermore, while relative disparities have decrease...
Source: Cancer Epidemiology Biomarkers and Prevention - November 13, 2014 Category: Cancer & Oncology Authors: McCarthy, A. M., Yang, J., Armstrong, K. Tags: Screening and Early Detection: Poster Presentations - Proffered Abstracts Source Type: research

Nanoparticles used to treat damaged arteries
Conclusion This exciting study in mice has shown that nanoparticles can be manufactured to target the plaques that form in atherosclerosis, and help stabilise them. It appears that the nanoparticles honed in on the plaques, rather than affecting other organs such as the spleen or liver, which gives an early indication that there may not be substantial side effects. However, it will be necessary to see if the same holds true for other organs. As with all mice studies, they give an indication of the likely biological effects of a new technique, but they do not provide the full picture of what may happen in humans, especially...
Source: NHS News Feed - February 19, 2015 Category: Consumer Health News Tags: Heart/lungs Medical practice Medication Source Type: news

Occupational class differences in later life hospital use by women who survived to age 80: the Renfrew and Paisley prospective cohort study
Conclusion: in this population, there were no socio-economic gradients seen in hospital utilisation for general admissions in old age. However, occupational class was associated with mental health admissions, coronary heart disease, stroke and cancer.
Source: Age and Ageing - April 27, 2015 Category: Geriatrics Authors: Hart, C. L., McCartney, G., Watt, G. C. M. Tags: Short Reports Source Type: research

Inflammatory Claims About Inflammation
We all appreciate the elegance of simple solutions to complex problems. But we know too that simplicity can often masquerade as truth, hiding a more nuanced reality. Such is the case with inflammation, where pseudoscience, exaggerated claims, false promises, and dangerous oversimplification have dominated for too long. Here is a typical missive: "Inflammation controls our lives. Have you or a loved one dealt with pain, obesity, ADD/ADHD, peripheral neuropathy, diabetes, heart disease, stroke, migraines, thyroid issues, dental issues, or cancer? If you answered yes to any of these disorders you are dealing with inflammatio...
Source: Science - The Huffington Post - May 29, 2015 Category: Science Source Type: news

Reduction of risk of dying from tobacco-related diseases after quitting smoking in Italy.
CONCLUSIONS: Estimates of risk reduction by quitting smoking are useful to provide a sounder scientific basis for public health messages and clinical advice. PMID: 26108248 [PubMed - as supplied by publisher]
Source: Tumori - June 26, 2015 Category: Cancer & Oncology Tags: Tumori Source Type: research

Metabolic Burden and Disease and Mortality Risk Associated with Impaired Fasting Glucose in Elderly Adults
ConclusionIFG was an intermediary condition for heart disease, inflammation, and oxidative stress in elderly adults but not for 2‐year incident disease or all‐cause mortality. Longer‐term prospective studies are needed to clarify whether IFG in elderly adults portends greater morbidity and mortality.
Source: Journal of the American Geriatrics Society - July 3, 2015 Category: Geriatrics Authors: Katherine Samaras, John Crawford, Helen L. Lutgers, Lesley V. Campbell, Bernhard T. Baune, Ora Lux, Henry Brodaty, Julian N. Trollor, Perminder Sachdev Tags: Brief Reports Source Type: research

Effect of Low‐Density Lipoprotein Cholesterol Lowering by Ezetimibe/Simvastatin on Outcome Incidence: Overview, Meta‐Analyses, and Meta‐Regression Analyses of Randomized Trials
ABSTRACT This analysis investigated the extent of different outcome reductions from low‐density lipoprotein cholesterol (LDL‐C) lowering following ezetimibe/simvastatin treatment and the proportionality of outcome to LDL‐C reductions. The authors searched PubMed between 1997 and mid‐June 2015 (any language) and the Cochrane Library to identify all randomized controlled trials comparing ezetimibe/simvastatin with placebo or less intensive LDL‐C lowering. Risk ratios (RR) and 95% confidence intervals (CIs), standardized to 20 mg/dL LDL‐C reduction, were calculated for 5 primary outcomes (fatal and nonfatal) and...
Source: Clinical Cardiology - August 18, 2015 Category: Cardiology Authors: Costas Thomopoulos, George Skalis, Helena Michalopoulou, Costas Tsioufis, Thomas Makris Tags: Review Source Type: research

Consumption of nuts and risk of total and cause-specific mortality over 15 years
Conclusions Nut consumption was independently associated with a decreased risk of overall and vascular-disease mortality, particularly in women.
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 25, 2015 Category: Nutrition Source Type: research

Can HRT in early menopause cut heart disease risk?
ConclusionThis double-blind RCT found that women taking HRT less than six years after the menopause had slower artery wall thickening than those taking a placebo. This represented the main measure of atherosclerosis progression tested; other measures showed no difference, so the results were not as conclusive as they could have been. Women taking HRT 10 or more years after menopause also showed no difference in atherosclerosis progression compared with a placebo, further complicating the picture.An important limitation of this study is the lack of a patient relevant endpoint, such as cardiovascular events or mortality. Pre...
Source: NHS News Feed - April 1, 2016 Category: Consumer Health News Tags: Heart/lungs Medication Source Type: news