Elective lung cancer surgery in the COVID-19 era: how do we do it?
Authors: Bilkhu R, Billè A Abstract The coronavirus 2019 (COVID-19) pandemic has caused significant mortality around the world and the focus has been on reducing the number of infections. In order not to compromise treatment of oncology patients, reducing the number of patients with COVID-19 undergoing treatment is mandatory. We reviewed the experience of the National Institute of Cancer in Milan and compared it with our experience. PMID: 32462984 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - May 30, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Precocious pseudopuberty, a paraneoplastic manifestation: a report of 2 cases.
We describe 2 young children with β-hCG-secreting tumors presenting with signs of pubertal activation. In the first patient, a 16-month-old boy with hepatoblastoma, only initial signs of PPP at presentation were identifiable, with concomitant high levels of β-hCG. Although the tumor had good response to therapy, β-hCG levels were fluctuant until the tumor was resected surgically. The second patient, an 18-month-old boy with intracranial germ cell tumor, presented with clear signs of pubertal activation and genitalia enlargement with no initial alteration of sex hormones. In both cases, the oncologic response...
Source: Tumori - May 30, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Corrigendum.
Authors: PMID: 32458738 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - May 28, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Activity of lenvatinib plus everolimus combination in a heavily pretreated patient with papillary renal cell carcinoma: a case report.
CONCLUSION: According to immunohistologic and biological findings in our patient both on primary tumor and liver metastasis, we hypothesize that selected patients with metastatic pRCC, progressed to standard/available treatments (including angiogenic drugs, mTOR inhibitors, and immunotherapy) and dissociated response to everolimus, could benefit from adding lenvatinib to everolimus. PMID: 32458743 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - May 28, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Comparison of clinical and oncologic effectiveness between flexible 3-dimensional and bidimensional video-thoracoscopic surgery for lung cancer.
CONCLUSION: Nonrandomized comparison of different surgical approaches is challenging. In our experience, 3D-VATS was safe and effective and offered excellent operative perception and sensitivity, enabling safer dissection of hilar structures. The 3D-VATS system helped skilled surgeons beyond the boundaries of more oncologically aggressive surgery. PMID: 32458749 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - May 28, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Analysis of survival of patients with metastatic malignant pleural mesothelioma.
Authors: Bille A, Okiror L, Harling L, Pernazza F, Muzio A, Roveta A, Grosso F Abstract AIM: To report the outcomes and prognosis of patients with malignant pleural mesothelioma (MPM) who present with or develop metastases during treatment. METHODS: This is a retrospective observational study of patients diagnosed with MPM over 7 years. Metastases at presentation or during follow-up were recorded. Multivariate Cox regression was used to evaluate the relationship of clinicopathologic variables and overall survival (OS). Logistic regression was used for propensity score matching of patients to assess chemotherapy...
Source: Tumori - May 28, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Real-world efficacy and safety of pembrolizumab in patients with non-small cell lung cancer: a retrospective observational study.
CONCLUSION: The results of the present study suggest that pembrolizumab seems less effective in the real-life population than in the pivotal clinical trials in patients with NSCLC but remains an effective treatment option for patients with NSCLC. Longer follow-up is needed. PMID: 32458769 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - May 28, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Finalization of autologous stem cell transplant in complex and multirelapsed follicular lymphoma.
CONCLUSIONS: Stem cell transplantation has emerged as the standard of care for young patients with FL but may be effective also in complex and multirelapsed clinical cases. PMID: 32442038 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - May 24, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

A feasibility exploratory study of a novel modality of using patient-reported outcomes (PROsEXPLOR) in the real world.
CONCLUSIONS: Using sPQs in routine clinical practice was feasible and well-accepted by patients. PROs allowed us to recognize and promptly manage adverse events, reducing unplanned emergency department or hospital visits to zero. PMID: 32432979 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - May 21, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Magnetic resonance-guided radiotherapy feasibility in elderly cancer patients: proposal of the MASTER scoring system.
CONCLUSIONS: MRgRT appears to be feasible in elderly patients and the MASTER score is proposed to support clinical decision-making in recommending elderly patients for this technology. PMID: 32410505 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - May 17, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Primary leiomyosarcoma of the uterine cervix: report of 4 cases, systematic review, and meta-analysis.
Authors: Kiliç C, Yuksel D, Cakir C, Turkmen O, Kimyon Comert G, Başaran D, Turan T Abstract BACKGROUND: Primary cervical leiomyosarcomas (CLMS) constitute 21% of all cervical sarcomas. Because of their rarity, to our knowledge, fewer than 40 cases have been reported. The aim of this study is to evaluate the clinical and surgical-pathological features, prognosis, treatment options, and survival of primary CLMS. METHODS: A systematic review of the medical literature was conducted to evaluate articles about primary CLMS. The literature was searched between 1959 and May 2019. On final evaluation, there wer...
Source: Tumori - May 15, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Targeted next-generation sequencing as a diagnostic tool in gastrointestinal system cancer/polyposis.
CONCLUSION: The accumulation of analyses with multigene testing will increase the available data for cancer predisposition genes in hereditary gastrointestinal cancer/polyposis. Educational campaigns for prevention, efficient screening programs, and more personalized care based on the profile of individual patients are necessary. PMID: 32390558 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - May 13, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

PD-L1 expression level in different thymoma stages and thymic carcinoma: a meta-analysis.
Authors: Chen HF, Wu LX, Li XF, Zhu YC, Pan WW, Wang WX, Xu CW, Huang JH, Wu MH, Du KQ Abstract BACKGROUND: The immune checkpoint ligand, programmed cell death 1 ligand 1 (PD-L1), is expressed in various tumors and associated with response to drugs that target programmed cell death protein 1. Previous studies have estimated the level of PD-L1 expression among different stages of thymoma and thymic carcinoma to evaluate its potential use as a diagnostic factor; however, its varying expression level has been problematic. We conducted this meta-analysis of published literature to evaluate PD-L1 expression in thymomas ...
Source: Tumori - May 7, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Response of a comprehensive cancer center to the COVID-19 pandemic: the experience of the Fondazione IRCCS-Istituto Nazionale dei Tumori di Milano.
CONCLUSION: Applying filters to protect our comprehensive cancer center from COVID-19 spread contributed to guaranteeing cancer care during the COVID-19 crisis in Milan. A surveillance area and surgical triage allowed us to protect the hospital from as many as 33 patients infected with SARS-CoV-2. PMID: 32364028 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - May 6, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Use of a natural multicomponent mouthwash plus oral hygiene vs oral hygiene alone to prevent everolimus-induced stomatitis: the STOP multicenter, randomized trial.
CONCLUSION: This study showed that the use of a natural multicomponent mouthwash coupled with regular oral hygiene was able to reduce the severity and duration of everolimus-induced stomatitis in patients with RCC. TRIAL REGISTRATION NUMBER: ISRCTN14568888. PMID: 32364051 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - May 6, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Cost-effectiveness analysis of fruquintinib as third-line treatment for patients with metastatic colorectal cancer.
CONCLUSIONS: Addition of fruquintinib to BSC is not a cost-effective regimen in the third-line setting for patients with metastatic CRC from the Chinese societal perspective. PMID: 32354261 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - May 3, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Electronic cigarette use among Italian smokers: patterns, settings, and adverse events.
CONCLUSION: In Italy, most conventional cigarette smokers use electronic cigarettes where smoking conventional cigarettes is prohibited. About half of users reported 1 or more symptoms attributable to electronic cigarettes, despite the relatively short duration of use. PMID: 32338200 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - April 28, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Erector spine plane block as postoperative rescue analgesia in thoracic surgery.
CONCLUSION: The use of ESPB as postoperative rescue analgesia can offer several advantages due to effective rescue analgesia and safety that makes it easy to perform in the thoracic surgical ward or in an outpatient clinic setting. PMID: 32326829 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - April 26, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

The effect of systemic inflammation indexes and 18FDG PET metabolic parameters on survival in advanced lung adenocarcinoma.
CONCLUSION: Age and LMR parameters were prognostic for survival in Cox regression analysis. There was no correlation between 18FDG PET parameters and inflammatory indexes. PMID: 32326835 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - April 26, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Pleuropulmonary blastoma: a report from the TREP (Tumori Rari in Et à Pediatrica) Project.
CONCLUSIONS: The TREP Registry showed an excellent capacity for registering cases of PPB. Patients received homogeneous treatment after the TREP Project started. Long-term outcomes were excellent for type I and unsatisfactory for type II and III. Tumor invasiveness and IRS stage were of prognostic value. PMID: 32270754 [PubMed - in process] (Source: Tumori)
Source: Tumori - April 11, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Ultrasound-guided erector spinae block for post-thoracotomy pain syndrome in video-assisted thoracic surgery.
This article describes our experience with 5 patients with post-thoracotomy pain syndrome after video-assisted thoracoscopic lobectomies, treated with weekly erector spinae plane block. We injected corticosteroid and local anesthetic. At the end of the treatment period, pain scores decreased significantly. Our experience suggests that erector spinae plane block may have a role in the treatment of post-thoracoscopy pain syndrome. PMID: 32194005 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - March 22, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Corrigendum.
Authors: PMID: 32172676 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - March 18, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

High expression of RAD21 predicts poor survival in patients with operated non-small-cell lung cancer.
CONCLUSION: High RAD21 expression indicates poor survival in patients with NSCLC. RAD21 may become a novel prognostic biomarker and therapeutic target in patients with NSCLC. PMID: 32178590 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - March 18, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Cannabinoids use in adolescents and young adults with cancer: a single-center survey.
CONCLUSIONS: Cannabis use by patients may often be unknown to caregivers. Studying this subject may help to better define important therapeutic aspects of these substances. PMID: 32178596 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - March 18, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Response on DCE-MRI predicts outcome of salvage radiotherapy for local recurrence after radical prostatectomy.
CONCLUSIONS: Patients whose lesions disappear during follow-up have a better outcome than those with unchanged lesions after sRT alone. PMID: 32180511 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - March 18, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Adnexal masses in pregnancy: an updated review on diagnosis and treatment.
Authors: D'Ambrosio V, Brunelli R, Musacchio L, Del Negro V, Vena F, Boccuzzi G, Boccherini C, Di Donato V, Piccioni MG, Benedetti Panici P, Giancotti A Abstract Adnexal masses are not common in pregnancy. They are often discovered incidentally during routine ultrasound examinations. In general, 24%-40% of the cases are benign tumors; up to 8% are malignant tumors. Adnexal masses are usually asymptomatic, but sometimes can be responsible for abdominal or pelvic pain. Transvaginal and transabdominal ultrasound is essential to define the morphology of pelvic masses and to distinguish between benign and malignant case...
Source: Tumori - March 18, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Retrospective analysis of gastric cancer management in a real-world setting: a single-institution experience.
CONCLUSIONS: Our results confirm that resection is the standard surgical approach to GC, and that chemotherapy is not widely used in adjuvant and metastatic settings. Older age and comorbidities are associated with nontreatment. PMID: 32167020 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - March 15, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Chronic lymphocytic leukemia focus in the context of a cardiac mass in a pretreated patient: an exceptional incidental finding.
CONCLUSIONS: The concomitant presence of B-CLL in the context of an atrial myxoma is extremely rare. The best strategy to treat these cardiac hematologic malignancies is unclear. PMID: 32162585 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - March 14, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Patient-reported pain and other symptoms among breast cancer survivors: prevalence and risk factors.
Authors: Divella M, Vetrugno L, Bertozzi S, Seriau L, Carla C, Bove T Abstract OBJECTIVE: To investigate the prevalence and risk factors associated with chronic pain and other symptoms related to breast cancer 6 months after surgery. METHODS: In an observational study of 261 female breast cancer survivors treated between January 2017 and January 2018, patients were asked about their pain symptoms using a questionnaire that utilized the Numeric Rating Score (NRS) and the Douleur Neuropathique Score (DN4) for neuropathic pain; it also addressed phantom sensations and functional disorders on the ipsilateral should...
Source: Tumori - March 14, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Association of various dietary habits and risk of lung cancer: an updated comprehensive literature review.
Authors: Fakhri G, Al Assaad M, Tfayli A Abstract Lung cancer remains the leading cause of cancer death in both men and women worldwide. Tobacco smoking remains the single most important factor. Recent research has focused on the role of nutrition and dietary habits on lung tumorigenesis. With many individual reports on separate dietary aspects, no single review is available in the literature that summarizes the updated studies. To our knowledge, this is the first review that comprehensively reviews the updated literature on the effect of dietary habits on lung cancer. This review was concluded in February 2019 and...
Source: Tumori - March 5, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Safety and activity of radium-223 in metastatic castration-resistant prostate cancer: the experience of Istituto Nazionale dei Tumori.
CONCLUSIONS: Our study provides clinically useful real-world data on radium-223, highlighting the importance of multidisciplinary patient management to guarantee the best continuum of care for patients with mCRPC. PMID: 32116138 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - March 4, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Additional value of MRI-detected EMVI scoring system in rectal cancer: applicability in predicting synchronous metastasis.
CONCLUSIONS: mrEMVI positivity is an independent risk factor for synchronous distant metastasis in rectal cancer. mrEMVI score 4 is a stronger risk factor for synchronous metastasis than mrEMVI score 3 in rectal cancer. PMID: 32116150 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - March 4, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Management of lymphoma survivor patients in Italy: an evaluation by Fondazione Italiana Linfomi.
Authors: Minoia C, Bari A, Nassi L, Banzi R, Gerardi C, Lenti V, Calabrese M, Spina M, Guarini A Abstract Several outpatient models for the follow-up of cancer survivors have been developed worldwide. A multidisciplinary approach is often necessary to guarantee the best monitoring of long-term toxicities. Guidelines also indicate a close education on healthy lifestyles. In this context, we have analyzed the Italian follow-up modalities of lymphoma survivors, with the aim to have a starting line to hypothesize and plan the best model for Italian hematology centers. PMID: 32116159 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - March 4, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Effectiveness of home-based preoperative pulmonary rehabilitation in COPD patients undergoing lung cancer resection.
Authors: Rispoli M, Salvi R, Cennamo A, Di Natale D, Natale G, Meoli I, Gioia MR, Esposito M, Nespoli MR, De Finis M, Buono S, Corcione A, Lavoretano S, Bianco A, Fiorelli A, Curcio C, Perrotta F Abstract OBJECTIVE: To investigate the effectiveness of a home-based preoperative rehabilitation program for improving preoperative lung function and surgical outcome of patients with chronic obstructive pulmonary disease (COPD) undergoing lobectomy for cancer. METHODS: This was a prospective, observational, single-center study including 59 patients with mild COPD who underwent lobectomy for lung cancer. All patients a...
Source: Tumori - February 26, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Prevalence of human papillomavirus in archival head and neck cancer in the eastern Inner Mongolian Autonomous Region, China.
CONCLUSIONS: The prevalence of HPV in HNC from this area is very low. The lineage/sublineage classification of the 3 HPV types in HNC in this area is consistent with the previous reported data of HPV lineage distribution in cervical cancer within China. PMID: 32066343 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - February 20, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Recurrent thrombosis followed by Lazarus response in ROS1 rearranged NSCLC treated with crizotinib: a case report.
CONCLUSIONS: Cancer diagnosis should always be considered in patients with unprovoked thrombosis and, if NSCLC is diagnosed, genetic alterations should be always sought after. A possible relation between venous thromboembolism and oncogenic drivers, particularly for ALK translocations, has been hypothesized. Similarly to ALK-positive NSCLC, ROS1 rearranged disease has been associated with an increased thromboembolic risk. Further studies are needed to better evaluate this relation and to evaluate the potential benefit of a prophylactic anticoagulating treatment in this subset of patients. PMID: 32066344 [PubMed - as su...
Source: Tumori - February 20, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Low Tesla magnetic resonance guided radiotherapy for locally advanced cervical cancer: first clinical experience.
CONCLUSIONS: Despite the retrospective nature of the observations and the low number of enrolled patients, the application of MRgRT in LACC appears to be safe and feasible with a favorable toxicity profile and response rates comparable to gold standard, supporting the setup of larger prospective studies to investigate the potentialities of this new technology. PMID: 32066345 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - February 20, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Prognostic value of [18F]FDG PET/CT parameters in surgically resected primary lung adenocarcinoma: a single-center experience.
Authors: Ventura L, Scarlattei M, Gnetti L, Silini EM, Rossi M, Tiseo M, Sverzellati N, Bocchialini G, Musini L, Balestra V, Ampollini L, Rusca M, Carbognani P, Ruffini L Abstract OBJECTIVE: To evaluate the prognostic role of maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) measured by FDG-positron emission tomography (PET)/computed tomography (CT) in patients with primary lung adenocarcinoma undergoing surgical resection. METHODS: All consecutive patients undergoing curative surgery for primary lung adenocarcinoma at the Thoracic Surgery Unit of the Un...
Source: Tumori - February 16, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Health technology assessment-based approach to flow cytometric immunophenotyping of acute leukemias: a literature classification.
CONCLUSIONS: We assessed the literature on flow cytometric immunophenotyping of AL over 3 decades as the first step toward an evidence-based analysis of the impact of this technology on the clinical management of patients with AL. PMID: 32056511 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - February 16, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Nivolumab efficacy in leptomeningeal metastasis of renal cell carcinoma: a case report.
CONCLUSIONS: Meningeal carcinomatosis metastasis from renal cancer is a rare condition. Diagnosis is often challenging: the onset of nonspecific presenting symptoms could be initially attributed to bone involvement, side effects of oncologic therapy, or paraneoplastic syndromes. Our case suggests that nivolumab could be an effective and safe treatment option in patients with pretreated renal cancer with leptomeningeal metastasis. PMID: 32041500 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - February 13, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Anlotinib in treatment of an elderly patient with recurrent advanced SCLC.
CONCLUSION: This is the first report on the precise efficacy of anlotinib in the treatment of advanced small cell lung cancer. Anlotinib is an important option for patients with small cell lung cancer. PMID: 32031060 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - February 8, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Cell-free DNA BRAF V600E measurements during BRAF inhibitor therapy of metastatic melanoma: long-term analysis.
CONCLUSIONS: Monitoring of plasma BRAF p.V600E cfDNA concentrations in patients with metastatic melanoma on targeted therapy may have prognostic value. Undetectable cfDNA p.V600E before and during treatment was associated with a favorable prognosis. PMID: 32026754 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - February 7, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Does cytoreductive surgery followed by adjuvant chemo-radiotherapy decrease the risk of recurrence and death in stage III endometrial cancer?
CONCLUSIONS: Our study demonstrated that optimal cytoreduction is the most significant prognostic factor and adjuvant CRT seems to be associated with a significant decreased risk of recurrence in stage III EC. PMID: 32008470 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - February 6, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Palliative care: not only for treating symptoms: a case report.
CONCLUSION: We present a case that underlines the importance of specialized PC assessment not limited to the control of symptoms. The search for the etiopathogenesis of a patient's symptoms and the evaluation of overall clinical conditions may be necessary to plan appropriate diagnostic evaluations, target palliative therapies, and achieve effective symptom control. PMID: 32008478 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - February 6, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Soft tissue necrosis in patients treated with transoral robotic surgery and postoperative radiotherapy: preliminary results.
CONCLUSION: We found an acceptable toxicity profile of PORT performed after a TORS procedure. Diabetes mellitus might be a risk factor for STN. PMID: 31996091 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - February 1, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Duration of one-lung ventilation as a risk factor for postoperative pulmonary complications after McKeown esophagectomy.
Authors: Lai G, Guo N, Jiang Y, Lai J, Li Y, Lai R Abstract OBJECTIVE: To assess whether the duration of one-lung ventilation (OLV) affects postoperative pulmonary complications after McKeown esophagectomy for esophageal cancer. METHODS: A retrospective analysis of data stored in a database for esophageal cancer was carried out to identify predictors of postoperative pulmonary complications in patients undergoing McKeown esophagectomy at Sun Yat-sen University Cancer Center between 2010 and 2012. RESULTS: Patients in the OLV ⩾150 minutes group had a higher incidence of postoperative pulmonary complication...
Source: Tumori - January 24, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

T-shaped linear-stapled cervical esophagogastric anastomosis for minimally invasive esophagectomy: a pilot study.
CONCLUSION: The T-shaped linear-stapled cervical esophagogastric anastomosis is efficient, reliable, easy to perform, and associated with lower postoperative complication rate. PMID: 31955641 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - January 22, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

κ and λ urine free light chains: a new method for quantification.
CONCLUSIONS: The new immunochemical method has a satisfactory performance and almost perfect agreement with immunofixation electrophoresis and gives the advantage of FLC quantification. PMID: 31955649 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - January 22, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Trends of gallbladder cancer incidence, mortality, and diagnostic approach in urban Shanghai between 1973 and 2009.
CONCLUSIONS: Thirty-seven years of cancer registry data document a tremendous increase in incidence/mortality and a slight decline in incidence/mortality over the last decades for GBC, especially among women, in Shanghai. The development of diagnostic approaches and aging population may play important roles. PMID: 31950882 [PubMed - as supplied by publisher] (Source: Tumori)
Source: Tumori - January 18, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research

Relationship of radiometabolic biomarkers to KRAS mutation status and ALK rearrangements in cases of lung adenocarcinoma.
CONCLUSIONS: The small numbers of KRAS mutations and ALK rearrangements are the limitation of this study for evaluation of diagnostic imaging. The frequency of these genetic alterations was as reported in the literature. We believe that our work will contribute to future meta-analysis. PMID: 31910789 [PubMed - in process] (Source: Tumori)
Source: Tumori - January 10, 2020 Category: Cancer & Oncology Tags: Tumori Source Type: research