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Cancer: Brain Cancers

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Total 2156 results found since Jan 2013.

Intra-and peritumoral hemorrhage in the meningioma of a nonagenarian due to administration of direct oral anticoagulants after mechanical thrombectomy
CONCLUSION: Peritumoral edema representing a pial blood supply might be a significant factor associated with intracranial hemorrhage due to DOAC administration in patients with meningioma. The evaluation of hemorrhagic risk due to DOACs is important not only for meningioma but also for other brain tumor cases.PMID:37292413 | PMC:PMC10246366 | DOI:10.25259/SNI_18_2023
Source: Surgical Neurology International - June 9, 2023 Category: Neurosurgery Authors: Katsuyoshi Miyashita Kosuke Nambu Shio Kinami Kenshu Nogami Iku Nambu Yasuo Tohma Source Type: research

Can ‘toxic’ bilirubin treat a variety of illnesses?
Generations of medical and biology students have been instilled with a dim view of bilirubin. Spawned when the body trashes old red blood cells, the molecule is harmful refuse and a sign of illness. High blood levels cause jaundice, which turns the eyes and skin yellow and can signal liver trouble. Newborns can’t process the compound, and although high levels normally subside, a persistent surplus can cause brain damage. Yet later this year up to 40 healthy Australian volunteers may begin receiving infusions of the supposedly good-for-nothing molecule. They will be participating in a phase 1 safety trial, sponsored ...
Source: ScienceNOW - June 8, 2023 Category: Science Source Type: news

Comprehensive Update and Review of Clinical and Imaging Features of SMART Syndrome ADULT BRAIN
SUMMARY: Stroke-like migraine attacks after radiation therapy (SMART) syndrome is a delayed complication of cranial irradiation, with subacute onset of stroke-like symptoms including seizures, visual disturbance, speech impairment, unilateral hemianopsia, facial droop, and aphasia, often associated with migraine-type headache. The diagnostic criteria were initially proposed in 2006. However, the diagnosis of SMART syndrome is challenging because clinical symptoms and imaging features of SMART syndrome are indeterminate and overlap with tumor recurrence and other neurologic diseases, which may result in inappropriate clinic...
Source: American Journal of Neuroradiology - June 8, 2023 Category: Radiology Authors: Ota, Y., Liao, E., Shah, G., Srinivasan, A., Capizzano, A. A. Tags: ADULT BRAIN Source Type: research

A measurement for chronic pain is a scientific holy grail – and we’re getting closer | Abdul-Ghaaliq Lalkhen
People who have chronic pain without a visible injury are often not believed, but new research can help visualise that painMost people, including doctors, do not appreciate that the organ that produces pain is the brain. A broken bone, damaged tissue or a bleeding wound is often the focus, but the experience of pain is the sum total of more than just the physical injury – it is the result of information sent from our nerves being filtered through an individual’s unique psychological makeup, genetics, gender, beliefs, expectations, motivations and emotional context. Pain is therefore an individual experience, and often ...
Source: Guardian Unlimited Science - May 25, 2023 Category: Science Authors: Abdul-Ghaaliq Lalkhen Tags: Medical research Health Science Neuroscience UK news Stroke Cancer Back pain Diabetes Source Type: news

Neuroprotective effect of aloe emodin against Huntington's disease-like symptoms in R6/1 transgenic mice
Food Funct. 2023 May 16. doi: 10.1039/d3fo00156c. Online ahead of print.ABSTRACTAloe emodin is a natural anthraquinone derived from aloe or rhubarb, showing anti-renal fibrosis, anti-atherosclerosis and anti-cancer effects. Aloe emodin also shows neuroprotective effects in ischemic stroke rats. Naturally, anthraquinone derivatives generally have the effect of inhibiting the transforming growth factor-β1 (TGF-β1) pathway. There is an increase in the calcium/calmodulin-dependent protein kinase II (CaMKII) and TGF-β1 levels in both Huntington's disease (HD) patients' brains and HD transgenic mice. Thus, we hypothesized tha...
Source: Atherosclerosis - May 16, 2023 Category: Cardiology Authors: Nan Yan Shuai Wang Haotian Gao Jiaqi Chen Jiahui Cao Pengsheng Wei Xue Li Ying Yu Yan Wang Yalin Niu Yijie Wang Shuyuan Liu Ge Jin Source Type: research