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Total 2156 results found since Jan 2013.
The role of STING signaling in central nervous system infection and neuroinflammatory disease
This article is categorized under:
Neurological Diseases> Molecular and Cellular Physiology
Infectious Diseases> Molecular and Cellular Physiology
Immune System Diseases> Molecular and Cellular Physiology
Source: Wiley Interdisciplinary Reviews: Systems Biology and Medicine - January 12, 2023 Category: Biomedical Science Authors: Lauren E. Fritsch,
Colin Kelly,
Alicia M. Pickrell Tags: Advanced Review Source Type: research
DL-3-n-butylphthalide (NBP) alleviates poststroke cognitive impairment (PSCI) by suppressing neuroinflammation and oxidative stress
In this study, we aimed to investigate the influences of NBP on cognitive function in an ischemic reperfusion (I/R) rat model. Our results showed that NBP profoundly decreased neurological scores, reduced cerebral infarct areas and enhanced cerebral blood flow (CBF). NBP potently alleviated poststroke cognitive impairment (PSCI) including depression-like behavior and learning, memory and social cognition impairments, in I/R rats. NBP distinctly suppressed the activation of microglia and astrocytes and improved neuron viability in the ischemic brain. NBP inhibited the expression of inflammatory cytokines, including interleu...
Source: Frontiers in Pharmacology - January 11, 2023 Category: Drugs & Pharmacology Source Type: research
Feasibility and acceptability of the Resilient Living program among persons with stroke or brain tumor and their family caregivers
CONCLUSION: The study confirms prior research suggesting that interventions targeting resilience are feasible, but larger studies with more rigorous methods are needed to appreciate the influence of resilience interventions in persons with brain disorders and their caregivers. Further research is needed to identify the characteristics of those most likely to benefit from resilience interventions and the optimal timing of such interventions.PMID:36617758 | DOI:10.3233/NRE-220127
Source: NeuroRehabilitation - January 9, 2023 Category: Rehabilitation Authors: Lori M Rhudy Emily A Hines Ellen M Farr Sherry S Chesak Source Type: research
Corrigendum: Case report: Cryptogenic giant brain abscess caused by Providencia rettgeri mimicking stroke and tumor in a patient with impaired immunity
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research
Depletion of circ_0006459 protects human brain microvascular endothelial cells from oxygen-glucose deprivation-induced damage through the miR-940/FOXJ2 pathway
CONCLUSION: Depletion of circ_0006459 protected human brain microvascular endothelial cells from oxygen-glucose deprivation-induced damage through miR-940/FOXJ2 pathway, providing a promising therapeutic target for ischemic stroke.PMID:36608833 | DOI:10.1016/j.trim.2022.101780
Source: Transplant Immunology - January 7, 2023 Category: Transplant Surgery Authors: Wei Li Hong Pang Lin Xie Source Type: research
