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Specialty: Drugs & Pharmacology
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Total 5439 results found since Jan 2013.
Systematic review and cost-effectiveness analysis of the treatment of post-stroke spasticity with abobotulinumtoxinA compared to physiotherapy
CONCLUSION: The cost-effectiveness analyses show that aboBoNT-A together with physiotherapy would be a cost-effective treatment compared with physiotherapy alone, independently of the perspective considered.PMID:37507277 | DOI:10.1016/j.farma.2023.06.008
Source: Farmacia Hospitalaria - July 28, 2023 Category: Drugs & Pharmacology Authors: Mar ía Errea Rodríguez Mar ía Fernández Juan Del Llano Roberto Nu ño-Solinís Source Type: research
The Critical Role of Equilibrative Nucleoside Transporter-2 in Modulating Cerebral Damage and Vascular Dysfunction in Mice with Brain Ischemia-Reperfusion
ConclusionsEnt2 plays a critical role in modulating cerebral collateral circulation and ameliorating pathological events of brain ischemia and reperfusion injury.
Source: Pharmaceutical Research - July 27, 2023 Category: Drugs & Pharmacology Source Type: research
Transcription Factor EB: A Promising Therapeutic Target for Ischemic Stroke
This article describes the basic structure, regulation of transcriptional activity, and biological roles of TFEB relevant to ischemic stroke. Additionally, we explore the effects of TFEB on the various pathological processes underlying ischemic stroke and current therapeutic approaches. The information compiled here may inform clinical and basic studies on TFEB, which may be an effective therapeutic drug target for ischemic stroke.PMID:37491856 | DOI:10.2174/1570159X21666230724095558
Source: Current Neuropharmacology - July 26, 2023 Category: Drugs & Pharmacology Authors: Jie Shao Yue Lang Manqiu Ding Xiang Yin Li Cui Source Type: research
Global Economic Burden Associated with Chronic Kidney Disease: A Pragmatic Review of Medical Costs for the Inside CKD Research Programme
ConclusionGlobally, CKD carries a significant economic burden, which increases substantially with increasing disease severity. We identified significant gaps in published costs and inconsistent costing definitions. Cost-effective interventions that target primary prevention and disease progression are essential to reduce CKD burden. Our results can be used to guide cost collection and facilitate better comparisons across countries/regions to inform healthcare policy.
Source: Advances in Therapy - July 26, 2023 Category: Drugs & Pharmacology Source Type: research
Tizanidine induced hypotension: report of a case and review of literature
CONCLUSION: This patient highlights the need for close monitoring of patients receiving tizanidine co-medication with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers. These drugs have a synergistic effect on reducing the renin-angiotensin-aldosterone system, thereby hypotension and bradycardia.PMID:37489780 | DOI:10.2174/1574886318666230725113855
Source: Current Drug Safety - July 25, 2023 Category: Drugs & Pharmacology Authors: Roopali Mahajan Jayantee Kalita Source Type: research
Sovateltide: First Approval
This article summarizes the milestones in the development of sovateltide leading to this first approval for use in patients with ACIS.
Source: Drugs - July 24, 2023 Category: Drugs & Pharmacology Source Type: research
Towards a Systemic Concept of the Brain Ishemia Stroke: Monte Carlo Driven in Silico Model
CONCLUSION: For the first time, a mathematical model has been constructed that allows us to represent the spatial dynamics of the development of the affected area in ischemic stroke of the brain, taking into account neurovascular units as single morphofunctional structures.PMID:37469160 | DOI:10.2174/1871527322666230719111903
Source: CNS and Neurological Disorders Drug Targets - July 20, 2023 Category: Drugs & Pharmacology Authors: Valentin V Fursov Alexander V Ananiev Dmitry A Kuznetsov Source Type: research
