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Drug: Medroxyprogesterone

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Total 487 results found since Jan 2013.

Effects of a fertility-sparing re-treatment for recurrent atypical endometrial hyperplasia and endometrial cancer: a systematic literature review
J Gynecol Oncol. 2023 Mar 6. doi: 10.3802/jgo.2023.34.e49. Online ahead of print.ABSTRACTTo examine the effectiveness of progestin re-treatment for recurrent endometrial intraepithelial neoplasia (EIN), atypical endometrial hyperplasia (AH) and endometrial cancer (EC) following initial fertility-sparing treatment. A comprehensive systematic review and meta-analysis were conducted by an Expert Panel of the Japan Society of Gynecologic Oncology Endometrial Cancer Committee. Multiple search engines, including PubMed/MEDLINE and the Cochrane Database, were searched in December 2021 using the keywords "Endometrial neoplasms," "...
Source: Journal of Gynecologic Oncology - March 17, 2023 Category: OBGYN Authors: Isao Murakami Hiroko Machida Tohru Morisada Yasuhisa Terao Tsutomu Tabata Mikio Mikami Yasuyuki Hirashima Yoichi Kobayashi Tsukasa Baba Satoru Nagase Source Type: research

Getting Up to Date with What Works: A Systematic Review on the Effectiveness and Safety of Task Sharing of Modern Methods in Family Planning Services
CONCLUSION: The evidence suggests that self-injection of DMPA-SC and tubal ligation performed by associate clinicians are safe and effective. These findings should be complemented with the evidence on the feasibility and acceptability of task sharing of these methods. The review protocol was registered with PROSPERO CRD42021283336.PMID:36817856 | PMC:PMC9936454 | DOI:10.1155/2023/8735563
Source: Biomed Res - February 23, 2023 Category: Research Authors: Tieba Millogo Eunice Chomi Seni Kouanda Moazzam Ali Source Type: research

Invasiveness of endometrial cancer cell lines is potentiated by estradiol and blocked by a traditional medicine Guizhi Fuling at clinically relevant doses
Front Oncol. 2023 Jan 16;12:1015708. doi: 10.3389/fonc.2022.1015708. eCollection 2022.ABSTRACTThe Traditional Chinese medicine, Guizhi Fuling (here called Fuling), has been confirmed in meta-analysis studies to reduce recurrence of endometriosis and improve pregnancy outcomes; however, the possible use of Fuling as a fertility-preserving treatment in endometrial cancer has not previously been tested. Results here are the first to demonstrate dose-dependent inhibition of cell motility by Fuling in two endometrial cancer cell lines, classified as Grade I which is responsive to progesterone treatment, and Grade III (MFE-280) ...
Source: Cancer Control - February 2, 2023 Category: Cancer & Oncology Authors: Sidra Khan Alanah Varricchio Carmela Ricciardelli Andrea J Yool Source Type: research

Correction to: Incidence of Herpes Simplex Virus Type 2 Infection Among African Women Using Depot Medroxyprogesterone Acetate, a Copper Intrauterine Device, or a Levonorgestrel Implant for Contraception: A Nested Randomized Trial
Clin Infect Dis. 2023 Jan 23:ciac309. doi: 10.1093/cid/ciac309. Online ahead of print.NO ABSTRACTPMID:36689296 | DOI:10.1093/cid/ciac309
Source: Herpes - January 23, 2023 Category: Infectious Diseases Source Type: research

Obstetric outcomes after medroxyprogesterone acetate treatment for early stage endometrial cancer or atypical endometrial hyperplasia: a single hospital-based study
CONCLUSION: Pregnancy after MPA therapy is associated with a high risk of placenta accreta. In cases in which the frequency of D&C is high, placenta accreta should be considered.PMID:36662363 | DOI:10.1007/s10147-023-02297-y
Source: Cancer Control - January 20, 2023 Category: Cancer & Oncology Authors: Maki Oishi Yoshifumi Kasuga Yuka Fukuma Asuka Hamuro Junko Tamai Yuya Tanaka Keita Hasegawa Takuma Yoshimura Satoru Ikenoue Daigo Ochiai Wataru Yamagami Mamoru Tanaka Source Type: research

Corrigendum to "Aberrant upregulation of CDK1 contributes to medroxyprogesterone acetate (MPA) resistance in cancer-associated fibroblasts of the endometrium" Biochem. Biophys. Res. Commun. 628 (2022) 133-140
Biochem Biophys Res Commun. 2022 Dec 31:S0006-291X(22)01736-3. doi: 10.1016/j.bbrc.2022.12.065. Online ahead of print.NO ABSTRACTPMID:36593136 | DOI:10.1016/j.bbrc.2022.12.065
Source: Biochemical and Biophysical Research communications - January 2, 2023 Category: Biochemistry Authors: Intan Sofia Omar Noor Azmi Mat Adenan Alejandro Godoy Ik Hui Teo Yogeeta Gunasagran Ivy Chung Source Type: research

Contraceptive exposure associates with urinary tract infection risk in a cohort of reproductive-age women: a case control study
CONCLUSION: This study notes potential for a small increase in UTIs with contraceptive use. Prospective studies are required before this information is applied in clinical settings.CONDENSATION: Although non-barrier contraception is commonly prescribed, the risk of urinary tract infections (UTI) with contraceptive exposure is poorly understood. This large-cohort, case-control study notes potential for a small increase in UTIs with contraceptive use.PMID:36537554 | DOI:10.1080/13625187.2022.2156278
Source: The European Journal of Contraception and Reproductive Health Care - December 20, 2022 Category: Reproduction Medicine Authors: Claire Lo Abin Abraham Cosmin A Bejan Seth A Reasoner Mario Davidson Loren Lipworth David M Aronoff Source Type: research