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Specialty: Allergy & Immunology

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Total 1296 results found since Jan 2013.

IL-24 Contributes to Neutrophilic Asthma in an IL-17A-Dependent Manner and Is Suppressed by IL-37
CONCLUSIONS: IL-24 aggravated neutrophilic airway inflammation by increasing epithelium-derived IL-17A production, which could be suppressed by IL-37. Targeting the IL-24/IL-17A signaling axis is a potential strategy, and IL-37 is a potential candidate agent for alleviating neutrophilic airway inflammation in asthma.PMID:36174993 | DOI:10.4168/aair.2022.14.5.505
Source: Allergy, Asthma and Immunology Research - September 29, 2022 Category: Allergy & Immunology Authors: Kang-Ni Feng Ping Meng Min Zhang Xiao-Ling Zou Shuang Li Chu-Qin Huang Ke-Fang Lai Hong-Tao Li Tian-Tuo Zhang Source Type: research

1,25(OH) < sub > 2 < /sub > D < sub > 3 < /sub > promotes the elimination of Klebsiella pneumoniae infection by inducing autophagy through the VDR-ATG16L1 pathway
CONCLUSIONS: The present study demonstrated the protective features of 1,25(OH)2D3 in macrophages against Kp infection and may provide evidence for further exploration of its potential as an adjunctive therapy agent for the treatment of bacterial infections.PMID:36174418 | DOI:10.1016/j.intimp.2022.109266
Source: International Immunopharmacology - September 29, 2022 Category: Allergy & Immunology Authors: Jinhui Tang Liwen Gu Jieyu Luo Haihua Luo Qingli Zeng Yong Jiang Source Type: research