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Prenatal Diagnosis and Molecular Cytogenetic Analyses of a de novo Deletion on Chromosome 4p16.3p15.33
Altern Ther Health Med. 2023 Sep 15:AT8915. Online ahead of print.ABSTRACTWolf-Hirschhorn syndrome (WHS) (OMIM 194190) is a contiguous gene syndrome with an estimated prevalence of around 1 in 50,000 births. The syndrome is caused by the deletion of a critical region (Wolf-Hirschhorn Syndrome Critical region-WHSCR) on chromosome 4p16.3. Its core features are typical facial gestalt, growth retardation, intellectual disability, developmental delay, and seizures. Prenatal diagnosis of WHS helps clinicians and parents make informed decisions about pregnancy management. In this research, a 31-year-old woman (gravida 1, para 0) ...
Source: Alternative Therapies in Health and Medicine - September 14, 2023 Category: Complementary Medicine Authors: Huili Luo Ruijie Chang Fangfang Liu Xia Gao Source Type: research

Magnetic Localization of Breast Lesions: A Large-Scale European Evaluation in a National Cancer Institute
CONCLUSIONS: Image-guided localization with magnetic seeds is an easy, safe, reliable, and effective method for localizing nonpalpable breast lesions. Both radiologists and surgeons agreed that the technology was intuitive to use and that it can be widely applied in preoperative localization in breast units.PMID:37704563 | DOI:10.1016/j.clbc.2023.08.004
Source: Clinical Breast Cancer - September 13, 2023 Category: Cancer & Oncology Authors: Catherine Depretto Gianmarco Della Pepa Claudia De Berardinis Laura Suman Claudio Ferranti Monica Marchesini Ilaria Maugeri Gabriele Martelli Massimiliano Gennaro Secondo Folli Giancarlo Pruneri Gianfranco Paride Scaperrotta Source Type: research

Intravascular Ultrasound in Detection of Bridging Stent Graft Instability During Fenestrated and Branched Endovascular Aneurysm Repair Procedures: A Multicentre Study on 274 Target Vessels
CONCLUSION: This study suggests that IVUS is a safe and potentially valuable adjunct imaging technology for intra-operative detection of TVV instability. Further long term investigations on larger cohorts are required to validate these promising results and to compare IVUS with alternative technologies in terms of efficiency, radiation exposure, procedural time, and costs.PMID:37704100 | DOI:10.1016/j.ejvs.2023.09.009
Source: PubMed: Eur J Vasc Endovasc ... - September 13, 2023 Category: Surgery Authors: Giuseppe Asciutto Abdulhakim Ibrahim Nicola Leone Gennai Stefano Michele Piazza Michele Antonello Anders Wanhainen Kevin Mani David Lindstr öm Lisa Struk Alexander Oberhuber Source Type: research

Nondeformed Ultrasound Image Production Method for Ultrasound-Guided Radiotherapy
Conclusion: The pixel displacement-based deformation correction method can solve the limitation imposed by image deformation on image alignment in US-guided radiotherapy. Compared with USdef, the alignment results of USrev with CT were better.PMID:37700675 | DOI:10.1177/15330338231194546
Source: Technology in Cancer Research and Treatment - September 13, 2023 Category: Cancer & Oncology Authors: Qixuan Li Fan Zhang Qianyi Xi Zhuqing Jiao Xinye Ni Source Type: research

Clinical Observation and Analysis of Thyroglossal Duct Cyst Carcinoma: A Report of 5 Cases
This study aimed to address these gaps by analyzing and summarizing the clinical features of 5 cases of papillary carcinoma arising in thyroglossal duct cysts (TGDC).Five patients with papillary carcinoma in TGDC treated by modified Sistrunk's procedure were included. Their clinical manifestation, physical examination findings, iconography, pathological findings, treatment, and outcomes were analyzed in aiding the diagnosis and treatment of TGDCCa. Immunohistochemistry was used to confirm the papillary carcinoma subtype. The BRAFV600E mutation was detected in 2 patients. No evidence of cancer recurrence, distant metastases...
Source: Ear, Nose and Throat Journal - September 13, 2023 Category: ENT & OMF Authors: Lei Lei Min Chen Zongguo Pang Jian Zou Lin Ma NingYing Song Jifeng Liu Source Type: research

Comparison of ultrasound elastography, magnetic resonance elastography and finite element model to quantify nonlinear shear modulus
Phys Med Biol. 2023 Sep 13. doi: 10.1088/1361-6560/acf98c. Online ahead of print.ABSTRACTThe aim of this study is to validate the estimation of the nonlinear shear modulus (A) from the acoustoelasticity theory with two experimental methods, ultrasound (US) elastography and magnetic resonance elastography (MRE), and a finite element method.
Experiments were performed on agar (2%) - gelatin (8%) phantom considered as homogeneous, elastic and isotropic. Two specific setups were built to ensure a uniaxial stress step by step on the phantom, one for US and a nonmagnetic version for MRE. The stress was controlled identic...
Source: Physics in Medicine and Biology - September 13, 2023 Category: Physics Authors: Gwena ël Pagé Marion Bied Philippe Garteiser Bernard Van Beers Nicolas Etaix Christophe Fraschini Aline Bel-Brunon Jean-Luc Gennisson Source Type: research

Deep learning for fast denoising filtering in ultrasound localization microscopy
Phys Med Biol. 2023 Sep 13. doi: 10.1088/1361-6560/acf98f. Online ahead of print.ABSTRACTSuper-resolution ultrasound (SR-US) microvascular imaging has important implications in the diagnosis of tumor growth and metastasis. Addition of a denoising filter step in ultrasound localization microscopy (ULM) imaging has been shown to effectively reduce the error localizations of microbubbles (MBs) and improve the resolution of SR-US imaging. However, previous image-denoising methods (e.g., block-matching 3-D, BM3D), required long data acquisition and processing times,which made ULM only able to be processed offline. To overcome...
Source: Physics in Medicine and Biology - September 13, 2023 Category: Physics Authors: Xiangyang Yu Shunyao Luan Shuang Lei Jing Huang Zeqing Liu Xudong Xue Teng Ma Yi Ding Benpeng Zhu Source Type: research

The correlation between prenatal ultrasound and MRI in isolated periventricular pseudocysts: Analysis of 10 years' experience at the University Hospital of Angers
CONCLUSION: The finding of periventricular cysts in antenatal ultrasound should lead to a reference ultrasound, a key procedure for distinguishing between SEPC and FHC. In our study, no additional benefit from MRI and TFU was established for the evaluation of FHC. These findings should be considered as normal variants, thus limiting pre- and postnatal investigations. The visualization of SEPC, THC, or a parenchymal abnormality on the reference ultrasound should lead to an additional MRI being performed and a personalized follow-up of the child.PMID:37704521 | DOI:10.1016/j.arcped.2023.06.010
Source: Archives de Pediatrie - September 13, 2023 Category: Pediatrics Authors: Alis ée Pengam Benoit Delorme Fran çoise Boussion Patrick Van Bogaert Pierre-Emmanuel Bouet Didier Loisel Source Type: research

Operative hysteroscopy versus ultrasound-guided electric vacuum aspiration for removal of retained products of conception: A prospective cohort study
CONCLUSION: In our cohort study, no significant differences in IUAs or complications were found. RPOC removal with HR was more often complete than removal with EVA, and additional therapeutic hysteroscopy was less frequently required after HR. These findings need to be correlated with those of RCTs.CLINICAL TRIAL REGISTRATION: The study was registered in de Dutch Trial Register (NTR4923). Date of registration 23-11-2014. Date of first enrollment 01-01-2015. https://trialsearch.who.int/Trial2.aspx?TrialID=NTR4923.PMID:37701632 | PMC:PMC10493502 | DOI:10.1016/j.eurox.2023.100230
Source: Reproductive Biology - September 13, 2023 Category: Reproduction Medicine Authors: Liselot P Wagenaar Hubertus A van Vliet Celine M Radder Louisette W Peters Steven Weyers Benedictus C Schoot Tjalina W Hamerlynck Source Type: research

Does unenhanced computerized tomography as imaging standard post-retrograde intrarenal surgery paradoxically reduce stone-free rate and increase additional treatment for residual fragments? Outcomes from 5395 patients in the FLEXOR study by the TOWER group
CONCLUSIONS: CT is the only reliable imaging to assess the burden of RFs following RIRS and urologist should consider at least one CT scan to determine the same and definitely plan reintervention only based on CT rather than ultrasound and X-ray combination.PMID:37701535 | PMC:PMC10493056 | DOI:10.1177/17562872231198629
Source: Adv Data - September 13, 2023 Category: Epidemiology Authors: Vineet Gauhar Daniele Castellani Ben Hall Chew Daron Smith Chu Ann Chai Khi Yung Fong Jeremy Yuen-Chun Teoh Olivier Traxer Bhaskar Kumar Somani Thomas Tailly Source Type: research

Ultrasound-guided acupotomy for trigger finger: a systematic review and meta-analysis
CONCLUSION: Our systematic review and meta-analysis can prove the effectiveness and safety of ultrasound-guided acupotomy in the treatment of trigger finger, but this still needs to be verified by a clinical standard large sample test.PMID:37705066 | DOI:10.1186/s13018-023-04127-3
Source: Hand Surgery - September 13, 2023 Category: Surgery Authors: Yong-Shan Liang Ling-Yan Chen Yao-Yun Cui Chun-Xiao Du Yun-Xiang Xu Lun-Hui Yin Source Type: research

Does unenhanced computerized tomography as imaging standard post-retrograde intrarenal surgery paradoxically reduce stone-free rate and increase additional treatment for residual fragments? Outcomes from 5395 patients in the FLEXOR study by the TOWER group
CONCLUSIONS: CT is the only reliable imaging to assess the burden of RFs following RIRS and urologist should consider at least one CT scan to determine the same and definitely plan reintervention only based on CT rather than ultrasound and X-ray combination.PMID:37701535 | PMC:PMC10493056 | DOI:10.1177/17562872231198629
Source: Adv Data - September 13, 2023 Category: Epidemiology Authors: Vineet Gauhar Daniele Castellani Ben Hall Chew Daron Smith Chu Ann Chai Khi Yung Fong Jeremy Yuen-Chun Teoh Olivier Traxer Bhaskar Kumar Somani Thomas Tailly Source Type: research

Translational strategies and systems biology insights for blood-brain barrier opening and delivery in brain tumors and Alzheimer's disease
Biomed Pharmacother. 2023 Sep 11;167:115450. doi: 10.1016/j.biopha.2023.115450. Online ahead of print.ABSTRACTThe blood-brain barrier (BBB) plays a critical role in determining the effectiveness of systemic treatments for brain diseases. Over the years, several innovative approaches in BBB opening and drug delivery have been developed and progressed into clinical testing phases, including focused ultrasound (FUS) with circulating microbubbles, mannitol-facilitated delivery of anti-neoplastic drugs, receptor-mediated transcytosis (RMT) by antibody-drug conjugates (ADCs), and viral vectors for gene therapy. We provided a com...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 13, 2023 Category: Drugs & Pharmacology Authors: Gefei Song Pierce Plumlee Ju Young Ahn Stephen Tc Wong Hong Zhao Source Type: research

Operative hysteroscopy versus ultrasound-guided electric vacuum aspiration for removal of retained products of conception: A prospective cohort study
CONCLUSION: In our cohort study, no significant differences in IUAs or complications were found. RPOC removal with HR was more often complete than removal with EVA, and additional therapeutic hysteroscopy was less frequently required after HR. These findings need to be correlated with those of RCTs.CLINICAL TRIAL REGISTRATION: The study was registered in de Dutch Trial Register (NTR4923). Date of registration 23-11-2014. Date of first enrollment 01-01-2015. https://trialsearch.who.int/Trial2.aspx?TrialID=NTR4923.PMID:37701632 | PMC:PMC10493502 | DOI:10.1016/j.eurox.2023.100230
Source: Reproductive Biology - September 13, 2023 Category: Reproduction Medicine Authors: Liselot P Wagenaar Hubertus A van Vliet Celine M Radder Louisette W Peters Steven Weyers Benedictus C Schoot Tjalina W Hamerlynck Source Type: research

Evaluation of the efficacy of ultrasound-guided radiofrequency ablation of papillary thyroid microcarcinoma after one year
CONCLUSION: Ultrasound-guided radiofrequency ablation is safe and effective for treating single-focus micropapillary thyroid carcinoma while retaining thyroid function, with few and minor complications, which can be used as an ideal surgical option.PMID:37704471 | DOI:10.1016/j.asjsur.2023.08.218
Source: Asian Journal of Surgery - September 13, 2023 Category: Surgery Authors: Shixiong Wang Nan Yao Zhenzhen Guo Ning Mao Hongtao Wu Fan Xu Jinmao Li Source Type: research