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Condition: Pregnancy

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Total 69693 results found since Jan 2013.

Both C57BL/KsJ (H2 d haplotype) and CB10-H2 (H2 b haplotype) mice are highly susceptible to congenital toxoplasmosis
In conclusion, the high IFN-γ and TNF serum levels observed in C57BL/KsJ (H2d) and CB10-H2 (H2b) mice were involved in the poor pregnancy outcomes in congenital toxoplasmosis. In addition, the higher IFN-γ, IL-6 and TNF levels detected in C57BL/KsJ in relation to CB10-H2 mice on 8dP/8dI seem to be related to the genetic background of C57BL/6J mice that may have contributed to the worse pregnancy outcome in this mouse lineage.PMID:37716667 | DOI:10.1016/j.actatropica.2023.107022
Source: Acta Tropica - September 16, 2023 Category: Infectious Diseases Authors: Loyane Bertagnolli Coutinho M ário Cézar de Oliveira Ester Cristina Borges Araujo Fl ávia Batista Ferreira França Marcos Paulo Oliveira Almeida Yusmaris Cariaco Paulo Czarnewski Neide Maria Silva Source Type: research

Both C57BL/KsJ (H2 d Haplotype) and CB10-H2 (H2 b Haplotype) Mice are Highly Susceptible to Congenital Toxoplasmosis
In conclusion, the high IFN-γ and TNF serum levels observed in C57BL/KsJ (H2d) and CB10-H2 (H2b) mice were involved in the poor pregnancy outcomes in congenital toxoplasmosis. In addition, the higher IFN-γ, IL-6 and TNF levels detected in C57BL/KsJ in relation to CB10-H2 mice on 8dP/8dI seem to be related to the genetic background of C57BL/6J mice that may have contributed to the worse pregnancy outcome in this mouse lineage.PMID:37716667 | DOI:10.1016/j.actatropica.2023.107022
Source: Acta Tropica - September 16, 2023 Category: Infectious Diseases Authors: Loyane Bertagnolli Coutinho M ário Cézar de Oliveira Ester Cristina Borges Araujo Fl ávia Batista Ferreira França Marcos Paulo Oliveira Almeida Yusmaris Cariaco Paulo Czarnewski Neide Maria Silva Source Type: research

Relationship between Dental Caries Experience and the Levels of Streptococcus mutans and Lactobacillus in Saliva of Pregnant Women
This study aims to correlate dental caries experience with Streptococcus mutans and lactobacillus levels in saliva using real-time PCR. This case-control analytical study conducted in Erbil City, Iraq, between 2021 and 2023 used a Cariogram to assess tooth decay risk and a real-time PCR assay to detect oral bacteria. Kurdish chewing gum with oil extract was used to stimulate saliva production. The chance of preventing tooth decay was 50.57% in pregnant women and 60.26% in non-pregnant women, with a statistically significant difference. The correlation between caries risk categories and Streptococcus mutans and Lactobacillu...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Fighan Jalal Hussein Sazan Sherdl Saleem Khalid Abdulaziz Merdad Source Type: research

Phagocytosis by macrophages promotes pancreatic β cell mass reduction after parturition in mice
Dev Cell. 2023 Aug 19:S1534-5807(23)00398-2. doi: 10.1016/j.devcel.2023.08.002. Online ahead of print.ABSTRACTElucidating the mechanism(s) modulating appropriate tissue size is a critical biological issue. Pancreatic β cells increase during pregnancy via cellular proliferation, but how β cells promptly decrease to the original amount after parturition remains unclear. Herein, we demonstrate the role and mechanism of macrophage accumulation in this process. In the final stage of pregnancy, HTR1D signaling upregulates murine β cell CXCL10, thereby promoting macrophage accumulation in pancreatic islets via the CXCL10-CXCR3...
Source: Developmental Cell - September 16, 2023 Category: Cytology Authors: Akira Endo Junta Imai Tomohito Izumi Yohei Kawana Hiroto Sugawara Masato Kohata Junro Seike Haremaru Kubo Hiroshi Komamura Toshihiro Sato Yoichiro Asai Shinichiro Hosaka Shinjiro Kodama Kei Takahashi Keizo Kaneko Hideki Katagiri Source Type: research

Restoring prefrontal cortical excitation-inhibition balance with cannabidiol ameliorates neurobehavioral abnormalities in a mouse model of neurodevelopmental disorders
Neuropharmacology. 2023 Sep 14:109715. doi: 10.1016/j.neuropharm.2023.109715. Online ahead of print.ABSTRACTMaternal immune activation (MIA) resulting from viral infections during pregnancy is linked to increased rates of neurodevelopmental disorders in offspring. However, the mechanisms underlying MIA-induced neurobehavioral abnormalities remain unclear. Here, we used a poly (I:C)-induced MIA mouse model to demonstrate the presence of multiple behavioral deficits in male offspring. Through RNA sequencing (RNA-seq), we identified significant upregulation of genes involved in axonogenesis, synaptogenesis, and glutamatergic ...
Source: Neuropharmacology - September 16, 2023 Category: Drugs & Pharmacology Authors: Lu Zhang Chunqiao Lin Jiushuang Zhu Yan He Meng Zhan Xiuwen Xia Ni Yang Kun Yang Baojia Wang Zhanqion Zhong Yili Wang Weijun Ding Youjun Yang Source Type: research

The protective value of trait mindfulness for mothers' anxiety during the perinatal period
CONCLUSIONS: For pregnant women who are at risk for developing or experiencing high levels of anxiety, it may be beneficial to participate in a mindfulness training with special attention for the attitudinal aspects of mindfulness.PMID:37716215 | DOI:10.1016/j.actpsy.2023.104034
Source: Acta Psychologica - September 16, 2023 Category: Psychiatry & Psychology Authors: Anna F Leyland Myrthe G B M Boekhorst Julia E Offermans Lisa-Marie Emerson Lianne P Hulsbosch Eva S Potharst Source Type: research

Safety of antenatal predniso(lo)ne and dexamethasone on fetal, neonatal and childhood outcomes: a systematic review
CONCLUSIONS: Based on the limited evidence found in this systematic review, predniso(lo)ne may have less side-effects compared to dexamethasone in short- and long-term outcomes. Current literature shows minimal risk of side-effects in the newborn by administration of a prenatal predniso(lo)ne dose of up to 10 mg per day.PMID:37715964 | DOI:10.1210/clinem/dgad547
Source: The Journal of Clinical Endocrinology and Metabolism - September 16, 2023 Category: Endocrinology Authors: Elise M A Slob Jacqueline U M Termote Janna W Nijkamp Hetty J Van der Kamp Erica L T van den Akker Source Type: research

Uptake of signposting to web-based resources: pregnant women's use of a preventive web-based intervention
CONCLUSION: The data offer unique opportunities to assess the utilisation of a web-based mental health-promotion intervention following advice from a clinician. This study draws conclusions about which patients are likely to access similar resources and which practice characteristics encourage their use.TRIAL REGISTRATION: Registered in clinicaltrials.gov, Trial number: NCT04129359 Date of registration: 16/10/2019 ( https://clinicaltrials.gov/ct2/show/NCT04129359 ).PMID:37716967 | PMC:PMC10504765 | DOI:10.1186/s12875-023-02130-5
Source: Primary Care - September 16, 2023 Category: Primary Care Authors: Emil R ønn Sørensen Ida Scheel Rasmussen Gritt Overbeck Volkert Siersma Clara Lundmark Appel Philip Wilson Source Type: research

The role and expression of pro/antiangiogenic factors and microRNAs in gestational hypertension and pre-eclampsia
CONCLUSION: This study provides better insights into angiogenic factors and microRNAs specificity to the subtypes of gestational hypertensive disorders in pregnancy. Relative expression analysis of angiogenic factors and microRNAs showed possible novel characteristics of gestational hypertension, and potential common molecular and pathological profiles with pre-eclampsia. Furthermore, we postulate that sEng and miR29B could be early detection markers for pre-eclampsia and gestational hypertension, respectively.PMID:37716201 | DOI:10.1016/j.ejogrb.2023.09.012
Source: Reproductive Biology - September 16, 2023 Category: Reproduction Medicine Authors: Nerolen Soobryan Ajit Kumar Jagidesa Moodley Irene Mackraj Source Type: research

European consensus statement on expert colposcopy
DISCUSSION: The agreed standards included colposcopy in pregnancy and post-menopause, investigation and management of glandular abnormalities, persistent high-risk HPV+ with normal/low-grade cytology, colposcopy management of type 3 transformation zones (TZ), high-grade cytology and normal colposcopy, colposcopy adjuncts, follow-up after treatment with CIN next to TZ margins and follow-up after treatment with CIN with persistent HPV+, and more. These standards are under review to create a final paper of consensus standards for dissemination to all EFC and ESGO members.PMID:37716200 | DOI:10.1016/j.ejogrb.2023.08.369
Source: Reproductive Biology - September 16, 2023 Category: Reproduction Medicine Authors: A E McGee T Alibegashvili K Elfgren B Frey M Grigore A Heinonen R Jach K Jariene V Kesic V K üppers M Kyrgiou S Leeson J Louwers M Mazurec J Mergui A Pedro A Šavrova E Siegler U Tabuica D Trojnarska M Trzeszcz R Turyna N Volodko M E Cruickshank European Source Type: research

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