Non-traumatic complete cervical spine dislocation with severe fixed kyphosis: successful multidisciplinary approach to a challenging case
ConclusionThis case illustrates the successful management of a critical situation based on a multidisciplinary collaboration involving radiologists, anesthesiologists, and spine surgeons. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - April 1, 2024 Category: General Medicine Source Type: research

Therapeutic efficacy and safety of JAK inhibitors in treating polymyositis/dermatomyositis: a single-arm systemic meta-analysis
DiscussionIn summary, this meta-analysis demonstrated that JAK inhibitors can potentially treat DM/PM without severe adverse reactions.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42023416493, identifier CRD42023416493. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - March 21, 2024 Category: Allergy & Immunology Source Type: research

Polymyositis is a rare and favourable outcome subtype of idiopathic inflammatory myopathy in Chinese patients
CONCLUSIONS: Strictly defined typical PM is a rare clinical subtype in Chinese IIM patients. Typical PM patients with classical pathology were MSA-negative and responded well to treatment and had a favourable prognosis. It is crucial for clinicians to combine clinical, serological, and pathological features to properly distinguish PM from other IIM subtypes.PMID:38488095 | DOI:10.55563/clinexprheumatol/7v9d2x (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 15, 2024 Category: Rheumatology Authors: Chao Sun Xiaolan Tian Hongxia Yang Hanbo Yang Shanshan Li Wei Jiang Qinglin Peng Guochun Wang Xin Lu Source Type: research

Risk of death, thrombotic and hemorrhagic events in anticoagulated patients with atrial fibrillation and systemic autoimmune diseases: an analysis from a global federated dataset
ConclusionAF patients with SAD are associated with a high risk of all-cause death, thrombotic, and hemorrhagic events. These patients merit careful follow-up and integrated care management to improve their prognosis.Graphical Abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - March 6, 2024 Category: Cardiology Source Type: research

Quantitative whole-body muscle MRI in idiopathic inflammatory myopathies including polymyositis with mitochondrial pathology: indications for a disease spectrum
AbstractObjectiveInflammatory myopathies (IIM) include dermatomyositis (DM), sporadic inclusion body myositis (sIBM), immune-mediated necrotizing myopathy (IMNM), and overlap myositis (OLM)/antisynthetase syndrome (ASyS). There is also a rare variant termed polymyositis with mitochondrial pathology (PM-Mito), which is considered a sIBM precursor. There is no information regarding muscle MRI for this rare entity. The aim of this study was to compare MRI findings in IIM, including PM-Mito.MethodsThis retrospective analysis included 41 patients (7 PM-Mito, 11 sIBM, 11 PM/ASyS/OLM, 12 IMNM) and 20 healthy controls. Pattern of ...
Source: Journal of Neurology - March 5, 2024 Category: Neurology Source Type: research

A bibliometric analysis of the research status and trends in studies on polymyositis and dermatomyositis with interstitial lung disease from 2000 to 2022 using Web of Science
ConclusionThis study found that research on PM/DM with ILD has increased over time, and scholars are paying more attention to this field. The development of new drugs for the management, treatment, and prevention of PM/DM with ILD is the primary task of researchers and a direction for future research in this field. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - February 20, 2024 Category: Allergy & Immunology Authors: Xiao ‐Na Ma, Wei Feng, Shu‐Lin Chen, Xiao‐Qin Zhong, Xue‐Xia Zheng, Chang‐Song Lin, Qiang Xu Tags: REVIEW ARTICLE Source Type: research