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Nutrition: Potassium
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How To Avoid China ’ s Medicine Monopoly
I want to share a shocking statistic with you…
Around 80% of all the pharmaceuticals sold in America — both prescription and over-the-counter — are manufactured in China.
I’m talking about drugs for Parkinson’s and Alzheimer’s, blood pressure and blood thinners, diuretics, aspirin, antibiotics, and a big chunk of the world’s insulin and diabetes drugs — just to name a few.1
We don’t even make penicillin anymore. The last penicillin plant in the U.S. closed its doors in 2004.
Americans who rely on medicine are now almost entirely at the mercy of a country whose relations with the U.S. have become more ...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news
Duloxetine HCl Alleviates Asthma Symptoms by Regulating PI3K/AKT/mTOR and Nrf2/HO-1 Signaling Pathways
AbstractAsthma is an inflammatory disease characterized by airway hyperresponsiveness, airway remodeling, and airway inflammation. In recent years, the prevalence of asthma has been increasing steadily and the pathogenesis of asthma varies from person to person. Due to poor compliance or resistance, existing drugs cannot achieve the desired therapeutic effect. Therefore, developing or screening asthma therapeutic drugs with high curative effects, low toxicity, and strong specificity is very urgent. Duloxetine HCl (DUX) is a selective serotonin and norepinephrine reuptake inhibitor, and it was mainly used to treat depressio...
Source: Inflammation - August 30, 2023 Category: Allergy & Immunology Source Type: research
75 year old dialysis patient with nausea, vomiting and lightheadedness
Written by Jesse McLaren A 75 year-old patient with diabetes and end stage renal
disease was sent to the ED after dialysis for three days of nausea, vomiting,
loose stool, lightheadedness and fatigue. RR18 sat 99% HR 90 BP 90/60, afebrile. Below is the 15 lead ECG. What do you think? There ’s normal sinus rhythm, normal conduction, normal axis,
normal R wave progression and normal voltages. There’s subtle inferior ST
elevation with straightening of the ST segment, reciprocal ST depression and T
wave inversion in aVL, and ST depression in V2. This is diagnostic of
infero-posterior OMI, but it is falsely n...
Source: Dr. Smith's ECG Blog - August 19, 2023 Category: Cardiology Authors: Jesse McLaren Source Type: blogs
What does the ECG show in this patient with chest pain, hypotension, dyspnea, and hypoxemia?
Written by Pendell Meyers, with some edits by SmithA man in his 40s with many comorbidities presented to the ED with chest pain, hypotension, dyspnea, and hypoxemia.The bedside echo showed a large RV (Does this mean there is a pulmonary embolism as the etiology?)Here is his triage ECG:What do you think? Lots of info here.The rhythm is 2:1 atrial flutter. The flutter waves can conceal or mimic ischemic repolarization findings, but here I don ' t see any obvious findings of OMI or subendocardial ischemia.The QRS is around 100 msec wide (narrow), but with very abnormal morphology including a large R-wave in V1, dee...
Source: Dr. Smith's ECG Blog - August 14, 2023 Category: Cardiology Authors: Pendell Source Type: blogs
Use of finer needles for venipuncture increases in vitro haemolysis despite reducing persistent pain and nerve injury: a retrospective study
CONCLUSION: Using finer needles involves both advantages and disadvantages, and careful consideration is needed to determine which type of needle is in the best interests of the patient.PMID:37542363 | DOI:10.1177/00045632231196045
Source: Clinical Biochemistry - August 5, 2023 Category: Biochemistry Authors: Hiroshi Umemura Hiromichi Takahashi Yoshiaki Fukuda Hitoshi Soma Rumiko Aoki Norihisa Takei Tomohiro Nakayama Source Type: research
Levcromakalim provokes an acute rapid-onset migraine-like phenotype without inducing cortical spreading depolarization
ConclusionsSingle LVC administration induced the fastest manifestation and recovery of acute migraine-like phenotype which was not mediated by CSD waves in the cerebral cortex. We suppose LVC triggered rapid-onset migraine-like symptoms are probably related to functional alterations in the trigeminal nociceptive system and K+ channel opening properties of LVC. Understanding the neurobiological mechanisms of this nociceptive window, may provide a novel target in migraine treatment.
Source: The Journal of Headache and Pain - July 24, 2023 Category: Neurology Source Type: research
Correction: Chloroquine inhibits vasodilation induced by ATP-sensitive potassium channels in isolated rat aorta
Gen Physiol Biophys. 2023 Jul;42(4):383. doi: 10.4149/gpb_2023014.ABSTRACTAnother affiliation: 2 Department of Anesthesiology and Pain Medicine, Gyeongsang National University College of Medicine, Jinju-si, Gyeongsangnam-do, Republic of Korea was added for the author Kyeong-Eon Park at his own request.PMID:37449322 | DOI:10.4149/gpb_2023014
Source: General Physiology and Biophysics - July 14, 2023 Category: Physiology Authors: Kyeong-Eon Park Soo Hee Lee Sung Il Bae Yeran Hwang Seong-Ho Ok Dawon Kang Seung Hyun Ahn Gyujin Sim Jin Kyeong Park Ju-Tae Sohn Source Type: research
