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Nutrition: Potassium
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Total 1055 results found since Jan 2013.
Clinical Effects of Biling Weitong Granules in Combination with Quadruple Therapy on Refractory Helicobacter pylori Infection
CONCLUSIONS: The combination of BLWTG and standard four-drug therapy had a high eradication rate and low recurrence rate in patients with refractory HP infection. Additionally, this combined therapy could regulate inflammatory reactions and reduce drug-related adverse reactions.PMID:37083648
Source: Alternative Therapies in Health and Medicine - April 21, 2023 Category: Complementary Medicine Authors: Ya-Lan Chen Zeng-Sheng Li Hui-Qing Zhang Da-Lei Chen Source Type: research
Clinical effects of hydration, supplementary vitamins, and trace elements during end-of-life care for cancer patients
CONCLUSION: we highlight the improvement in the control of most symptoms and some biochemical parameters in the intervention group receiving vitamins and oligoelements along with intravenous hydration. Further studies are needed.PMID:37073755 | DOI:10.20960/nh.04446
Source: Nutricion Hospitalaria - April 18, 2023 Category: Nutrition Authors: Dana Aline P érez-Camargo Silvia Rosa Allende-P érez M ónica M Rivera-Franco V íctor Itaí Urbalejo-Ceniceros Mar ía de la Luz Sevilla-González Cinthya E Arzate-Mireles Erika Thalia Copca-Mendoza Source Type: research
Dual contribution of ASIC1a channels in the spinal processing of pain information by deep projection neurons revealed by computational modeling
This study supports a dual contribution to windup of calcium permeable ASIC1a channels in deep laminae projecting neurons, promoting it upon moderate channel activity, but ultimately leading to calcium-dependent windup inhibition associated to potassium channels when activity increases.
Source: PLoS Computational Biology - April 17, 2023 Category: Biology Authors: Magda Chafa ï Source Type: research
A sensory neuron-specific long non-coding RNA reduces neuropathic pain by rescuing KCNN1 expression
AbstractNerve injury to peripheral somatosensory system causes refractory neuropathic pain. Maladaptive changes of gene expression in primary sensory neurons are considered molecular basis of this disorder. Long non-coding RNAs (lncRNAs) are key regulators of gene transcription; however, their significance in neuropathic pain remains largely elusive.Here, we reported a novel lncRNA, named sensory neuron-specific lncRNA (SS-lncRNA), for its expression exclusively in dorsal root ganglion (DRG) and trigeminal ganglion.SS-lncRNA was predominantly expressed in small DRG neurons and significantly downregulated due to a reduction...
Source: Brain - April 4, 2023 Category: Neurology Source Type: research
ATP-Gated Potassium Channels Contribute To Ketogenic Diet-Mediated Analgesia
Chronic pain is a substantial health burden, affecting 18-20% of American adults, and options for treating chronic pain remain minimally effective. Ketogenic diets are emerging as well-tolerated, effective therapeutic strategies in preclinical models of chronic pain, especially diabetic neuropathy. Here, we tested the hypothesis that a ketogenic diet provides analgesia through ketone oxidation and subsequent activation of ATP-gated potassium (KATP) channels. We demonstrated that intraplantar injection of noxious stimuli (methylglyoxal, cinnamaldehyde, or capsaicin) evoked nocifensive behaviors (licking, biting, lifting, et...
Source: The Journal of Pain - April 1, 2023 Category: Materials Science Authors: Jonathan Enders, Sarah Thomas, Paige Lynch, Jarrid Jack, Janelle M. Ryals, Patrycja Puchalska, Peter A. Crawford, Douglas E. Wright Source Type: research
Chronic Pain-Related Small Conductance Calcium-Activated Potassium (SK) Channel Plasticity In Mesolimbic Dopamine Neurons
Chronic pain is characterized by significant emotional-affective components contributing to treatment challenges. A hypodopaminergic state, characterized by decreased activity of ventral tegmental area (VTA) dopamine neurons, has been causally linked to development of pain-related anhedonia and amotivation, however the mechanisms underlying its genesis are poorly understood. The VTA is heterogeneous with discrete dopaminergic projections that play unique roles in reward processing. The dopaminergic projection to the nucleus accumbens (VTA->NAc) tracks subjective reward value, important for computing reward prediction errors.
Source: The Journal of Pain - April 1, 2023 Category: Materials Science Authors: Jeremy Thompson, Yu-Hsuan Chang, Alex Legaria, Meaghan C. Creed Source Type: research
New RYBREVANT ® (amivantamab-vmjw) Data Showed Long-Term Clinical Response and Safety in Patients with Advanced Non-Small Cell Lung Cancer with EGFR Exon 20 Insertion Mutations Who Have Failed Prior Platinum-Based Chemotherapy
COPENHAGEN, DENMARK, March 29, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new long-term data from the CHRYSALIS study evaluating RYBREVANT® (amivantamab-vmjw) in patients with advanced non-small cell lung cancer (NSCLC) and epidermal growth factor receptor (EGFR) exon 20 insertion mutations whose disease progressed on prior platinum-based chemotherapy.1 Data from the study showed long-term response and safety in this population and were presented in an oral presentation at the 2023 European Lung Cancer Congress (ELCC) (Abstract #779).1In the analysis of the CHRYSALIS study, inve...
Source: Johnson and Johnson - March 29, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
What is strange about this paroxysmal atrial fibrillation in an otherwise healthy patient? And what happened after giving ibutilide?
Conclusions.The efficacy of transthoracic cardioversion for converting atrial fibrillation to sinus rhythm was enhanced by pretreatment with ibutilide. However, use of this drug should be avoided in patients with very low ejection fractions. (N Engl J Med 1999;340:1849-54.) Smith comments from the full text: They included patients who had had a fib for less than 48 hours They excluded patients with a fib for longer than 48 hours unless they proved, by TE echo, to not have an atrial thrombus OR unless they anti-coagulated them for 3 weeks first *Therefore, our patients who have been in afib< 48 hours, or who h...
Source: Dr. Smith's ECG Blog - March 13, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs
