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Infectious Disease: Hepatitis C

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Total 16439 results found since Jan 2013.

Characterizing the cascade of care for hepatitis C virus infection among Status First Nations peoples in Ontario: a retrospective cohort study
CMAJ. 2023 Apr 11;195(14):E499-E512. doi: 10.1503/cmaj.220717.ABSTRACTBACKGROUND: As First Nations Peoples are a priority focus of Canada's commitment to eliminating hepatitis C virus (HCV) as a public health threat, understanding individuals' progression from diagnosis to cure can guide prioritization of elimination efforts. We sought to characterize and identify gaps in the HCV care cascade for Status First Nations peoples in Ontario.METHODS: In this retrospective cohort study, a partnership between the Ontario First Nations HIV/AIDS Education Circle and academic researchers, HCV testing records (1999-2018) for Status Fi...
Source: Canadian Medical Association Journal - April 11, 2023 Category: General Medicine Authors: Andrew B Mendlowitz Karen E Bremner Murray Krahn Jennifer D Walker William W L Wong Beate Sander Lyndia Jones Wanrudee Isaranuwatchai Jordan J Feld Source Type: research

Prevalence and Genotypes of Hepatitis C Infection Among Hemodialysis Patients in Bushehr, Iran
CONCLUSIONS: Considering the high seroprevalence of HCV in hemodialysis patients, regular screening of these patients for HCV infection and prompt treatment of those found infected are recommended.PMID:37073372 | PMC:PMC10105900 | DOI:10.5001/omj.2023.60
Source: Oman Medical Journal - April 19, 2023 Category: Middle East Health Authors: Reza Taherkhani Fatemeh Farshadpour Reza Asayesh Source Type: research

Reducing Barriers to Hepatitis C Treatment among Drug Users: An Integrated Hepatitis C Peer Education and Support Program.
This report describes an innovative HCV Peer Educator Program that facilitates education, support, and engagement in HCV treatment among patients in an opioid treatment program. Integrating peer educators in a collaborative manner with close supervision holds promise as a model to reduce barriers to HCV treatment among drug users. PMID: 24858874 [PubMed - in process]
Source: Journal of Health Care for the Poor and Underserved - May 30, 2014 Category: Global & Universal Authors: Roose RJ, Cockerham-Colas L, Soloway I, Batchelder A, Litwin AH Tags: J Health Care Poor Underserved Source Type: research

The search for nucleoside/nucleotide analog inhibitors of dengue virus.
This article forms part of a symposium in Antiviral Research on flavivirus drug discovery. PMID: 26241002 [PubMed - as supplied by publisher]
Source: Antiviral Research - August 1, 2015 Category: Virology Authors: Chen YL, Yokokawa F, Shi PY Tags: Antiviral Res Source Type: research

Impact of Education Provided by Nurses on Quality of Life, Anxiety, and Depression in Patients Receiving Hepatitis C Virus Therapy
The aim of this study was to determine the impact of education provided by a nurse on quality of life, anxiety, and depression in patients receiving hepatitis C virus (HCV) therapy. The total number of patients receiving HCV treatment was 25 patients (18 females and 7 males). Organized patient lectures addressed transmission routes of HCV, effects of virus on the liver, interferon treatment, treatment complications and care, and psychosocial problems faced by patients with HCV and their families. Lectures were followed by interviews in small groups including 3–4 patients each and repeated 3 months after. Data were collec...
Source: Gastroenterology Nursing - September 1, 2015 Category: Nursing Tags: Features Source Type: research

Next-Generation Sequencing of 5' Untranslated Region of Hepatitis C Virus in Search of Minor Viral Variant in a Patient Who Revealed New Genotype While on Antiviral Treatment.
In conclusion, longitudinal analysis of HCV variants, employing two independent deep sequencing methods, suggests that the transient presence of a different genotype strain in PBMC was a result of superinfection and not a selection of pre-existing minor variant. PMID: 26747069 [PubMed - as supplied by publisher]
Source: Advances in Experimental Medicine and Biology - January 16, 2016 Category: Research Tags: Adv Exp Med Biol Source Type: research

"Know More Hepatitis:" CDC's National Education Campaign to Increase Hepatitis C Testing Among People Born Between 1945 and 1965.
Authors: Jorgensen C, Carnes CA, Downs A Abstract In 2012, CDC issued recommendations calling for those born between 1945 and 1965, or baby boomers, to get tested for the hepatitis C virus. To help implement this recommendation, CDC developed "Know More Hepatitis," a multimedia national education campaign. Guided by behavioral science theories and formative research, the campaign used multiple strategies to reach baby boomers and health-care providers with messages encouraging baby boomers to get tested for hepatitis C. With a limited campaign budget, the "Know More Hepatitis" campaign relied mostly on donated time...
Source: Public Health Reports - May 13, 2016 Category: Global & Universal Tags: Public Health Rep Source Type: research

An update on recent developments in the search for hepatitis C virus therapies with pan-genotypic efficacy.
Authors: Borgia G, Scotto R, Buonomo AR Abstract INTRODUCTION: Pangenotypic drugs against HCV infections led to high rates of virologic response with very limited adverse events. Moreover, they are easy to administer among all HCV genotypes with minimal changes in treatment schedule. For this reason, the demand for new antivirals is greatly lowered. Areas covered. We discuss results from trials assessing safety and efficacy of Ravidasvir, which is the only direct-acting antiviral currently in clinical development. Expert opinion. The currently available pangenotypic drug combinations are very effective in HCV eradi...
Source: Expert Opinion on Investigational Drugs - April 6, 2019 Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research

Meta-regression analysis of sex-and birth year-specific prevalence of HBsAg and anti-HCV among un-.diagnosed Japanese: Data from the first-time blood donors, periodical health checkup, and the comprehensive health checkup with lifestyle education (Ningen Dock).
CONCLUSION: We could estimate the pooled prevalence of HBsAg and anti-HCV based on nationwide data. The result can be used reference data of various countermeasure for hepatitis eradication. PMID: 31447462 [PubMed - as supplied by publisher]
Source: Journal of Epidemiology - August 28, 2019 Category: Epidemiology Tags: J Epidemiol Source Type: research

Patients with hepatitis C lost to follow-up: ethical-legal aspects and search results.
CONCLUSION: a large number of patients with hepatitis C are lost to follow-up. Searching for and contacting these patients is legally and ethically viable. PMID: 32579001 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - June 25, 2020 Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research

Race, Education, and Gender Disparities in Transplantation of Kidneys From Hepatitis C Viremic Donors
Conclusions. Despite an increase in transplants from HCV NAT+ donors, we found substantial racial/ethnic disparities in transplantation of these kidneys. These data highlight how the benefits of a scientific breakthrough are often made less available to disadvantaged patients.
Source: Transplantation - July 28, 2021 Category: Transplant Surgery Tags: Original Clinical Science—General Source Type: research

Innovations in education: A prospective study of storytelling narratives to enhance hepatitis C virus knowledge among substance users
CONCLUSION: Storytelling narratives emphasizing HCV education appear to be an effective method to increase HCV-related knowledge among substance users. They should become an educational cornerstone to promote HCV management among this population.PMID:35721284 | PMC:PMC9157714 | DOI:10.4254/wjh.v14.i5.972
Source: World Journal of Hepatology - June 20, 2022 Category: Gastroenterology Authors: Andrew H Talal Yu-Xin Ding Marianthi Markatou Source Type: research