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Total 447 results found since Jan 2013.

Mammalian Meat Allergy Accompanied by Venom Allergy: A Review of 12 Cases.
In this study, we have emphasized that  Ixodes ricinus named tick type which is implicated in meat allergy, is found in domestic animals of Black Sea Region of Turkey. A new concept has been recently raized; suggesting that having an alpha-gal allergy is associated with an increased risk of sensitization to multiple venom spesific immunoglobulin (Ig) E. Our aim is to evaluate the clinical characteristics of adult patients with MMA and its relationship with insect sting reactions in Turkey. Patients referring to the allergy outpatient clinic with possible MMA were interviewed regarding reactions to a stinging insect. Demog...
Source: Iranian Journal of Allergy, Asthma and Immunology - October 22, 2019 Category: Allergy & Immunology Authors: Kutlu A, Unal D Tags: Iran J Allergy Asthma Immunol Source Type: research

Meat allergy associated with α‐Gal – Closing diagnostic gaps by anti‐α‐Gal IgE immune profiling
ConclusionsDetection of individual sensitization patterns with different α‐Gal‐containing analytes provides the basis for an individual allergy diagnosis for α‐Gal sensitized patients. Higher amounts of α‐Gal in pork and beef innards compared to muscle meat as indicated by a higher staining intensity are a plausible explanation for the difference in allergic symptom severity.This article is protected by copyright. All rights reserved.
Source: Allergy - July 3, 2017 Category: Allergy & Immunology Authors: U. Jappe, S. Minge, B. Kreft, A. Ludwig, B. Przybilla, A. Walker, R. Varga, P. Seidel, T. Biedermann, W. Anem üller, A. Kromminga, F. Ruëff, H. Merk, N. Wagner, R. Treudler, M. Worm, I. Waldmann, J. Saloga, W. M. Becker, T. Goldmann, T. A. Platts‐Mill Tags: Original Article: Experimental Allergy and Immunology Source Type: research

Clinical Features and Culprit Food Allergens of Korean Adult Food Allergy Patients: A Cross-Sectional Single-Institute Study.
CONCLUSIONS: Wheat, fruits with or without PFAS, and crustaceans are important and frequent causative allergens in Korean adult FA; these allergens differ from those found in childhood FA. It is notable that non-classic allergies, such as PFAS, FDEIA, and α-Gal allergy, are the important causes of anaphylaxis in Korean adult FA. PMID: 31332982 [PubMed]
Source: Allergy, Asthma and Immunology Research - July 25, 2019 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Angioedema Due to Lamiaceae Allergy.
We present a 13-year-old male childallergic to three different plants (Salvia officinalis, Mentha piperita and Origanum onites L.) of Lamiaceae family. The patient developed angioedema 20-30 minutes after eating chicken meat with cheddar cheese. There was no history of allergy. Oral food challenge (OFC) with both cheddar cheese and chicken meat was negative. Skin tests for inhalant allergens were negative. 3 weeks later, the patient was admitted with angioedema after drinking sage tea. OFC with sage was applied and angioedema was observed. It was recognized that the first trigger, chicken meat with cheddar cheese, in...
Source: Iranian Journal of Allergy, Asthma and Immunology - February 1, 2018 Category: Allergy & Immunology Authors: Yazıcı S, Nacaroglu HT, Bahçeci Erdem S, Karaman S, Can D Tags: Iran J Allergy Asthma Immunol Source Type: research

Red meat allergy in children and adults
Purpose of review To highlight recent advances in our understanding of the clinical features, prevalence, and pathophysiology of red meat allergy. Recent findings Allergic reactions to red (i.e. mammalian) meat have historically been considered rare and described primarily in young atopic children. It is now clear that red meat allergy is not uncommon in some parts of the world in other age groups. Strikingly, the majority of these cases relate to specific IgE to galactose-α-1,3-galactose, an oligosaccharide of nonprimate mammals. The mechanism of sensitization in this syndrome relates to bites of certain hard ticks ...
Source: Current Opinion in Allergy and Clinical Immunology - April 30, 2019 Category: Allergy & Immunology Tags: FOOD ALLERGY: Edited by Alessandro Fiocchi and Motohiro Ebisawa Source Type: research

Speculations on red meat allergy due to á-Gal; its connection to coronary artery disease, suggested dietary guidance and allergy testing.
Authors: Pitsios C, Dimitriou A, Vassilopoulou E PMID: 32729316 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - July 31, 2020 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

The quantity and quality of α‐gal‐specific antibodies differs in individuals with and without delayed red meat allergy
ConclusionPatients with delayed meat‐allergy display IgE and IgG Ab that selectively recognize the α‐gal‐epitope on BGG. Their enhanced α‐gal‐specific IgE levels are accompanied by high levels of α‐gal‐specific IgG1 devoid of IgE‐blocking activity. This subclass distribution is atypical for food allergies and distinct from natural α‐gal‐IgG responses in non allergic individuals.This article is protected by copyright. All rights reserved.
Source: Allergy - May 31, 2016 Category: Allergy & Immunology Authors: Dagmar Kollmann, Birgit Nagl, Christof Ebner, Waltraud Emminger, Stefan Wöhrl, Claudia Kitzmüller, Susanne Vrtala, Andreas Mangold, Hendrik‐Jan Ankersmit, Barbara Bohle Tags: Original Article: Experimental Allergy and Immunology Source Type: research

Galactose- α-1,3-galactose allergy: a rare syndrome and an atypical presentation.
In this study, we report the case of a 76-year-old male with an immediate reaction following the ingestion of red meat. Rigorous diagnostic exams, including prick test, prick-to-prick tests, serum specific IgE and SDS-PAGE IgE-immunoblotting, were performed. The α-gal epitope IgE re-turned a value of 35.3 kUA/L, leading the authors to believe that this is an atypical case of α-gal allergy. PMID: 29479927 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - February 27, 2018 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Red meat allergy induced by tick bites: A Norwegian case report.
Authors: Arslan Lied G Abstract Summary: Food allergies, especially delayed hypersensitivity reactions, are often challenging for both patients and clinicians. Here, we report the case of a 64-year-old man who had allergic reactions six hours after eating a meal containing red meat. He reported that he had several tick bites in months before the reaction. High serum specific IgE levels of alpha-gal confirmed the diagnosis of alpha-gal allergic reaction with delayed onset after red meat ingestion caused by tick bite. PMID: 28752723 [PubMed - in process]
Source: European Annals of Allergy and Clinical Immunology - July 30, 2017 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Meat reintroduction in a patient with alpha-gal allergy.
PMID: 29679764 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - April 18, 2018 Category: Allergy & Immunology Authors: Pelletier T, Alvarez-Arango S, Sameeta FNU, Manos E, Jerschow E Tags: Ann Allergy Asthma Immunol Source Type: research

Galactose- α-1,3-galactose syndrome: an Italian survey.
Conclusions. α-Gal syndrome is present in Italy and beef is the most frequent offending food. In most cases symptoms were not severe. PMID: 29249134 [PubMed - in process]
Source: European Annals of Allergy and Clinical Immunology - December 19, 2017 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Investigation into the α-Gal syndrome: Characteristics of 261 children and adults reporting red meat allergy
ConclusionsThe α-Gal syndrome is a regionally common form of food allergy that: has a characteristic but not universal delay in symptom onset; includes gastrointestinal symptoms; can develop at any time in life; and, is equally common in otherwise non-atopic individuals.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 31, 2019 Category: Allergy & Immunology Source Type: research

Poultry Meat allergy: a Review of Allergens and Clinical Phenotypes
AbstractPurpose of reviewIn the recent years, more cases of poultry meat allergy, both IgE- or non-IgE-mediated, are being reported. Patients have varied clinical reactivity at various levels of sensitivity to different meat preparations. The lack of validated biomarkers renders accurate diagnosis challenging. In this review, we aim to provide an overview of the current status of poultry meat allergy along with a description on the allergens implicated.Recent findingsPoultry meat allergy occurs as a result of cross-reactions with known allergens of egg yolk or bird feathers or as genuine IgE-mediated sensitivity to allerge...
Source: Current Treatment Options in Allergy - June 27, 2022 Category: Allergy & Immunology Source Type: research

Meat allergy associated with galactosyl ‐α‐(1,3)‐galactose (α‐Gal)—Closing diagnostic gaps by anti‐α‐Gal IgE immune profiling
ConclusionsDetection of individual sensitization patterns with different α‐Gal‐containing analytes provides the basis for an individual allergy diagnosis for α‐Gal‐sensitized patients. Higher amounts of α‐Gal in pork and beef innards compared to muscle meat as indicated by a higher staining intensity are a plausible explanation for the difference in allergic symptom severity.
Source: Allergy - August 15, 2017 Category: Allergy & Immunology Authors: U. Jappe, S. Minge, B. Kreft, A. Ludwig, B. Przybilla, A. Walker, R. Varga, P. Seidel, T. Biedermann, W. Anem üller, A. Kromminga, F. Ruëff, H. Merk, N. Wagner, R. Treudler, M. Worm, I. Waldmann, J. Saloga, W. M. Becker, T. Goldmann, T. A. Platts‐Mill Tags: ORIGINAL ARTICLE Source Type: research

Venom allergy is increased in alpha-gal allergy: shared environmental or immunologic factors?
Expansion of tick populations has been associated with environmental change. We now face a global increasing incidence of mammalian meat food allergy due to alpha-gal sIgE, which has been associated with tick bites. Since patients with alpha-gal allergy frequent the outdoor environment, we sought to determine whether rates of stinging insect venom allergy, another environmentally-influenced condition, are increased in these patients.
Source: Journal of Allergy and Clinical Immunology - February 1, 2018 Category: Allergy & Immunology Authors: Shivangi Choudhary, Maya R. Jerath, Scott P. Commins Source Type: research