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Total 373 results found since Jan 2013.
Researchers to target mosquito egg production to curtail disease
(University of California - Riverside) Entomologists at the University of California, Riverside, have received a five-year grant of $2.44 million from the National Institute of Allergy and Infectious Diseases to investigate the role hormones play in the female mosquito's ability to use human blood for egg production. The funding will allow the entomologists to introduce novel research tools for genetic manipulation, such as CRISPR, in their research.
Source: EurekAlert! - Infectious and Emerging Diseases - July 13, 2018 Category: Infectious Diseases Source Type: news
Subtype C ALVAC-HIV and bivalent subtype C gp120/MF59 HIV-1 vaccine in low-risk, HIV-uninfected, South African adults: a phase 1/2 trial
Publication date: Available online 18 June 2018 Source:The Lancet HIV Author(s): Linda-Gail Bekker, Zoe Moodie, Nicole Grunenberg, Fatima Laher, Georgia D Tomaras, Kristen W Cohen, Mary Allen, Mookho Malahleha, Kathryn Mngadi, Brodie Daniels, Craig Innes, Carter Bentley, Nicole Frahm, Daryl E Morris, Lynn Morris, Nonhlanhla N Mkhize, David C Montefiori, Marcella Sarzotti-Kelsoe, Shannon Grant, Chenchen Yu, Vijay L Mehra, Michael N Pensiero, Sanjay Phogat, Carlos A DiazGranados, Susan W Barnett, Niranjan Kanesa-thasan, Marguerite Koutsoukos, Nelson L Michael, Merlin L Robb, James G Kublin, Peter B Gilbert, Lawrence Corey, ...
Source: The Lancet HIV - June 19, 2018 Category: Infectious Diseases Source Type: research
The Global Face of Eosinophilic Esophagitis: Advocacy and Research Groups
AbstractAlthough eosinophilic esophagitis (EoE) has been described in the literature for a substantial period, its recognition as a disease entity on the global stage is still relatively new. It has become a major diagnosis of consideration by medical providers when both adult and pediatric patients present with dysphagia, food impaction, and gastroesophageal reflux-like symptoms. In addition to the clinical work of specialists such as allergy-immunologists and gastroenterologists, the evolution of research organizations and advocacy groups focused on EoE have greatly assisted in bringing attention to, and raising awarenes...
Source: Clinical Reviews in Allergy and Immunology - May 5, 2018 Category: Allergy & Immunology Source Type: research
Center for AIDS Research funding renewed for an old and on-going fight
(University of California - San Diego) The National Institute of Allergy and Infectious Diseases has awarded a five-year, $15 million grant to the San Diego Center for AIDS Research (CFAR) at UC San Diego, renewing support that extends back to an original establishing grant in 1994--the height of the AIDS epidemic.
Source: EurekAlert! - Medicine and Health - April 16, 2018 Category: International Medicine & Public Health Source Type: news
Funding will help uncover immune system differences that trigger food allergies
(Children's National Health System) Adora A. Lin, M.D., Ph.D., an attending physician in Children's department of Allergy and Immunology, was awarded $240,000 to improve understanding of how children's immune systems tolerate or react to certain food allergens -- sometimes triggering a cascade of side effects that can be fatal.
Source: EurekAlert! - Medicine and Health - April 13, 2018 Category: International Medicine & Public Health Source Type: news
There's an allergy epidemic in Africa, and not enough specialists to deal with it
(Elsevier) Allergies are on the rise in Africa, but with too few specialists to treat them, and a parallel increase in immune deficiency diseases, the situation is worse than we thought. According to researchers from Ain Shams University in Egypt in an article in The Journal of Allergy and Clinical Immunology, the answer is more funding, motivated governments and better scientific partnerships.
Source: EurekAlert! - Medicine and Health - April 4, 2018 Category: International Medicine & Public Health Source Type: news
Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial
Publication date: Available online 15 March 2018 Source:The Lancet Author(s): Zhi-Wei Lai, Ryan Kelly, Thomas Winans, Ivan Marchena, Ashwini Shadakshari, Julie Yu, Maha Dawood, Ricardo Garcia, Hajra Tily, Lisa Francis, Stephen V Faraone, Paul E Phillips, Andras Perl Background Patients with systemic lupus erythematosus have T-cell dysfunction that has been attributed to the activation of the mammalian target of rapamycin (mTOR). Rapamycin inhibits antigen-induced T-cell proliferation and has been developed as a medication under the generic designation of sirolimus. We assessed safety, tolerance, and efficacy of sirolimus ...
Source: The Lancet - March 16, 2018 Category: General Medicine Source Type: research
Notice of Intent to Publish a Funding Opportunity Announcement for Impact of Initial Influenza Exposure on Immunity in Infants (U01 Clinical Trial Not Allowed)
The National Institute of Allergy and Infectious Diseases (NIAID) is issuing this Notice to promote a new initiative that will solicit applications to support research to determine how initial and repeated natural influenza infections and/or influenza vaccinations shape infant and childhood immunity to future influenza exposures, through support of prospective longitudinal human infant cohorts.
Source: PHPartners.org - March 7, 2018 Category: International Medicine & Public Health Source Type: news
Raleigh pharma scores NIH funding, Rutgers partnership
With a $225,000 grant from the National Institute of Allergy and Infectious Diseases, a Raleigh firm is working with Rutgers New Jersey Medical School on the development of tuberculosis treatments.
Source: bizjournals.com Health Care:Physician Practices headlines - March 5, 2018 Category: American Health Authors: Jennifer Henderson Source Type: news
Why Flu Outbreaks Have Been the Worst in Nearly a Decade
The only thing worse than getting the flu is catching it after you’ve gotten a flu shot. It’s been a terrible year for outbreaks — the worst in almost a decade. Contributing to that is the high failure rate of this year’s vaccine. The current shot is just 25 percent effective against the H3N2 virus, this season’s most-often-identified strain by the Centers for Disease Control and Prevention. The experts say, with enough time and money, they can do a lot better.
“There has to be a wholesale change to how we make the flu vaccine,” said Amesh Adalja, senior scholar at Johns Hopkins Ce...
Source: TIME: Science - February 28, 2018 Category: Science Authors: Bloomberg Tags: Uncategorized Bloomberg flu healthytime onetime Source Type: news
DNA methylation in childhood asthma: an epigenome-wide meta-analysis
We examined epigenome-wide methylation using Illumina Infinium Human Methylation450 BeadChips (450K) in whole blood in 207 children with asthma and 610 controls at age 4–5 years, and 185 children with asthma and 546 controls at age 8 years using a cross-sectional case-control design. After identification of differentially methylated CpG sites in the discovery analysis, we did a validation study in children (4–16 years; 247 cases and 2949 controls) from six additional European cohorts and meta-analysed the results. We next investigated whether replicated CpG sites in cord blood predict later asthma in 1316 children. We ...
Source: The Lancet Respiratory Medicine - February 26, 2018 Category: Respiratory Medicine Source Type: research
Migration and risk of HIV acquisition in Rakai, Uganda: a population-based cohort study
Publication date: Available online 25 February 2018 Source:The Lancet HIV Author(s): Oluwasolape Olawore, Aaron A R Tobian, Joseph Kagaayi, Jeremiah M Bazaale, Betty Nantume, Grace Kigozi, Justine Nankinga, Fred Nalugoda, Gertrude Nakigozi, Godfrey Kigozi, Ronald H Gray, Maria J Wawer, Robert Ssekubugu, John S Santelli, Steven J Reynolds, Larry W Chang, David Serwadda, Mary K Grabowski Background In sub-Saharan Africa, migrants typically have higher HIV prevalence than non-migrants; however, whether HIV acquisition typically precedes or follows migration is unknown. We aimed to investigate the risk of HIV after migration ...
Source: The Lancet HIV - February 26, 2018 Category: Infectious Diseases Source Type: research
Researchers to develop new allergy relief device using cold plasma technology
(University of Liverpool) Researchers at the University of Liverpool have been awarded funding to develop an innovative device that uses cold plasma technology to tackle the problem of airborne allergens in the home.
Source: EurekAlert! - Medicine and Health - February 9, 2018 Category: International Medicine & Public Health Source Type: news
Which HIV-infected adults with high CD4 T-cell counts benefit most from immediate initiation of antiretroviral therapy? A post-hoc subgroup analysis of the START trial
Publication date: Available online 16 January 2018 Source:The Lancet HIV Author(s): Jean-Michel Molina, Birgit Grund, Fred Gordin, Ian Williams, Mauro Schechter, Marcello Losso, Matthew Law, Ernest Ekong, Noluthando Mwelase, Athanasios Skoutelis, Martin J Wiselka, Linos Vandekerckhove, Thomas Benfield, David Munroe, Jens D Lundgren, James D Neaton Background Immediate initiation of antiretroviral therapy (ART) in asymptomatic adults with CD4 counts higher than 500 cells per μL, as recommended, might not always be possible in resource-limited settings. We aimed to identify subgroups of individuals who would benefit most f...
Source: The Lancet HIV - January 17, 2018 Category: Infectious Diseases Source Type: research
Gene Therapy Developer Orchard Therapeutics Raises $110 Million Gene Therapy Developer Orchard Therapeutics Raises $110 Million
Orchard Therapeutics said on Wednesday it raised $110 million in the second round of funding as the drug developer looks to launch its gene therapy to treat a rare inherited disorder and beef up manufacturing facilities.Reuters Health Information
Source: Medscape Medical News Headlines - December 21, 2017 Category: Consumer Health News Tags: Allergy & Clinical Immunology News Source Type: news
