Why Flu Outbreaks Have Been the Worst in Nearly a Decade

The only thing worse than getting the flu is catching it after you’ve gotten a flu shot. It’s been a terrible year for outbreaks — the worst in almost a decade. Contributing to that is the high failure rate of this year’s vaccine. The current shot is just 25 percent effective against the H3N2 virus, this season’s most-often-identified strain by the Centers for Disease Control and Prevention. The experts say, with enough time and money, they can do a lot better. “There has to be a wholesale change to how we make the flu vaccine,” said Amesh Adalja, senior scholar at Johns Hopkins Center for Health Security. “We’re always setting ourselves up for vaccine mismatch and failures and the like because of the lead time in how long it takes the vaccines to be made.” Drug companies and public-health agencies are already grappling with the challenge of next year and beyond. Officials must decide several months ahead of flu season the make-up of the year’s vaccine. Flu shots are typically 40 percent to 60 percent effective in any given season, though this year fell short of that mark. The ultimate goal is a universal vaccine that would operate more like a measles inoculation than a vaccine targeted at a handful of strains of flu. The idea is to offer something closer to 90 percent protection against a disease for years — if not for life — with a single vaccine. It’s still early days. And out-maneuvering ...
Source: TIME: Science - Category: Science Authors: Tags: Uncategorized Bloomberg flu healthytime onetime Source Type: news

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Authors: Petretto DR, Masala I, Masala C Abstract School closure and home confinement are two of the measures of lockdown chosen by governments and policymakers all over the world to prevent and limit the spread of the infection of COVID-19. There is still an open debate about the real effect of school closure on the reduction of risk of infection on children and the risk of infection on with other age groups (parents, grandparents and others). There is an agreement on the effect of school closure in reducing and delaying the peak of the outbreak. In this Editorial, starting from the ongoing Italian experience, we ...
Source: Clinical Practice and Epidemiology in Mental Health - Category: Psychiatry Tags: Clin Pract Epidemiol Ment Health Source Type: research
Conclusions: The antiviral mouthwashes play a certainly important role in reducing the viral load of the salivary virus. In the present study, this importance could be proved in two different aspects, that is, the use of mouthwash before dental procedures to reduce the risk of transmission of the virus to the dental team and the use of this mouthwash in COVID-19 patients to help improve systemic problems associated with oral microbial flora. PMID: 32944152 [PubMed]
Source: Journal of Oral Microbiology - Category: Microbiology Tags: J Oral Microbiol Source Type: research
Publication date: Available online 14 July 2020Source: Journal of Emergency NursingAuthor(s): Yongchao Hou, Qian Zhou, Dongzhi Li, Yanhua Guo, Jingjing Fan, Juzi Wang
Source: Journal of Emergency Nursing - Category: Nursing Source Type: research
Authors: Jung SW, Kim YJ, Han SB, Lee KY, Kang JH Abstract OBJECTIVES: Since the 2000s, two lineages of the influenza B virus (influenza B/Victoria and influenza B/Yamagata) have been co-circulating. Information on the age distribution of patients infected by each influenza B virus lineage may be helpful for establishing differentiated influenza prevention and control strategies for each age group. METHODS: Age distributions were compared between patients infected by influenza A and B viruses and between those infected by the influenza B virus when B/Victoria and B/Yamagata lineages circulated dominantly. R...
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
Authors: Ossareh S, Bagheri M, Abbasi M, Abolfathi S, Bohlooli A Abstract INTRODUCTION: Seven months after the emergence of SARS-COV-2 virus, there is paucity of data regarding the epidemiology of the virus in hemodialysis patients. We aim to present the results of the screening program implied after outbreak of COVID-19 in a referral hemodialysis ward. METHODS: We started clinical screening and obligatory mask wearing for dialysis patients and personnel on 20-Feb-2020. However 11 symptomatic COVID-19 patients emerged till day +36. On days +39 and +40 a screening program was implied including measurement of SAR...
Source: Iranian Journal of Kidney Diseases - Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research
Authors: Arenas MD PMID: 32943243 [PubMed - as supplied by publisher]
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - Category: Urology & Nephrology Tags: Nefrologia Source Type: research
Publication date: Available online 19 September 2020Source: Microbes and InfectionAuthor(s): Nina Marí G.P. de Queiroz, Fabio V. Marinho, Marcelo A. Chagas, Luciana C.C. Leite, E. Jane Homan, Mariana T.Q. de Magalhães, Sergio C. Oliveira
Source: Microbes and Infection - Category: Infectious Diseases Source Type: research
AbstractNon-occupational post-exposure prophylaxis (nPEP) has been clinically recommended since 2005. HIV providers and non-HIV providers (n = 480) practicing within above-average HIV prevalence ZIP codes of the 10 U.S. cities with greatest overall HIV prevalence participated in a cross-sectional survey between July 2014 and May 2015. Providers were asked about their awareness of post-exposure prophylaxis (PEP) and nPEP prescribing experience for patients with potential sexual exposures to HIV, which we coded into a PEP prescribing cascade with three categories: (1) PEP unaware, (2) PEP aware, no nPEP prescri...
Source: AIDS and Behavior - Category: Infectious Diseases Source Type: research
AbstractBetween October 2015 and March 2018, we conducted the Modified Antiretroviral Treatment Access Study (MARTAS), a nurse-delivered case management intervention to improve linkage-to-care for persons recently tested HIV positive. Adult participants from nine urban clinics in three regions of Ukraine were randomized to either MARTAS or standard of care (SOC) using individual, parallel, two-arm design. The main study outcome was linkage-to-care (defined as registration at an HIV clinic) within a 3-month period from enrollment in the study. Intention-to-treat analysis of MARTAS (n  = 135) versus SOC (n&thin...
Source: AIDS and Behavior - Category: Infectious Diseases Source Type: research
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