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Infectious Disease: Influenza
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Total 693 results found since Jan 2013.
Pro-inflammatory Effects of Influenza Type A Virus PB1-F2 Protein-derived Peptide in Lipopolysaccharide-treated Macrophages.
Abstract
Influenza A virus (IAV) has the potential to cause pandemics with considerable health and socio-economic burdens. A viral protein, polymerase basic 1- frame2 (PB1-F2), as a virulence factor, has pro-apoptotic activity and contributes to viral pathogenesis by delaying viral clearance and inducing inflammation. Macrophages are susceptible to IAV infection and produce high levels of inflammatory cytokines and chemokines. In the present study, the pro-inflammatory effects of PB1-F2 derived peptide was evaluated by measuring the expression of key inflammatory mediators in murine macrophage cell line J774.1. PB...
Source: Iranian Journal of Allergy, Asthma and Immunology - May 16, 2020 Category: Allergy & Immunology Authors: Kalantar K, Farzaneh Z, Gholijani N, Hosseini SY, Bani Hasan E Tags: Iran J Allergy Asthma Immunol Source Type: research
Comparing COVID-19, Flu Death Tolls ' Extremely Dangerous ' Comparing COVID-19, Flu Death Tolls ' Extremely Dangerous '
COVID-19 numbers are actual death counts, whereas rates of influenza deaths are estimated from algorithms. Comparing the two is dangerous and inaccurate, authors of a new perspective article say.Medscape Medical News
Source: Medscape Allergy Headlines - May 14, 2020 Category: Allergy & Immunology Tags: Infectious Diseases News Source Type: news
Knowledge of Aspergillosis Complicating Influenza Knowledge of Aspergillosis Complicating Influenza
How much do physicians know about pulmonary aspergillosis in patients with influenza, and what knowledge gaps remain?Emerging Infectious Diseases
Source: Medscape Allergy Headlines - May 8, 2020 Category: Allergy & Immunology Tags: Infectious Diseases Journal Article Source Type: news
Smell and taste symptom ‐based predictive model for COVID‐19 diagnosis
ConclusionSmell or taste change is a strong predictor for a COVID ‐19 positive test result. Using the presence of smell or taste change with fever, this parsimonious classifier correctly predicts 75% of COVID‐19 test results. A larger cohort of respondents will be necessary to refine classifier performance.This article is protected by copyright. All rights reserved
Source: International Forum of Allergy and Rhinology - May 3, 2020 Category: Allergy & Immunology Authors: Lauren T. Roland,
Jose G. Gurrola,
Patricia A. Loftus,
Steven W. Cheung,
Jolie L. Chang Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Preserved cellular immunity upon influenza vaccination in most patients with common variable immunodeficiency
Publication date: Available online 21 April 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): David Friedmann, Sigune Goldacker, Hans-Hartmut Peter, Klaus Warnatz
Source: The Journal of Allergy and Clinical Immunology: In Practice - April 22, 2020 Category: Allergy & Immunology Source Type: research
“Host immune response-inspired development of the influenza vaccine”
Influenza is a respiratory illness caused by influenza viruses. It is a major public health concern with a huge economic impact worldwide [1 –3]. Vaccines against influenza virus are the best method of protection. The very young, the elderly, pregnant women and immune-compromised individuals are at enhanced risk for severe complications during infection. Therefore, these individuals form special target groups for influenza vaccination. Due to the rise in life expectancy, the elderly population is growing in countries with an aging population.
Source: Annals of Allergy, Asthma and Immunology - April 19, 2020 Category: Allergy & Immunology Authors: Angela Choi, Adolfo Garc ía-Sastre, Michael Schotsaert Tags: Review Source Type: research
Host immune response –inspired development of the influenza vaccine
To assess the current and future development of influenza vaccines.
Source: Annals of Allergy, Asthma and Immunology - April 19, 2020 Category: Allergy & Immunology Authors: Angela Choi, Adolfo Garc ía-Sastre, Michael Schotsaert Tags: Review Source Type: research
"Host immune response-inspired development of the influenza vaccine".
PMID: 32325117 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - April 19, 2020 Category: Allergy & Immunology Authors: Choi A, García-Sastre A, Schotsaert M Tags: Ann Allergy Asthma Immunol Source Type: research
Smell dysfunction: a biomarker for COVID ‐19
ConclusionsQuantitative smell testing demonstrates that decreased smell function, but not always anosmia, is a major marker for SARS ‐CoV‐2 infection and suggests the possibility that smell testing may help, in some cases, to identify COVID‐19 patients in need of early treatment or quarantine.This article is protected by copyright. All rights reserved
Source: International Forum of Allergy and Rhinology - April 16, 2020 Category: Allergy & Immunology Authors: Shima T. Moein,
Seyed M.R. Hashemian,
Babak Mansourafshar,
Ali Khorram ‐Tousi,
Payam Tabarsi,
Richard L. Doty Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Vaccines, Antibodies and Drug Libraries. The Possible COVID-19 Treatments Researchers Are Excited About
In early April, about four months after a new, highly infectious coronavirus was first identified in China, an international group of scientists reported encouraging results from a study of an experimental drug for treating the viral disease known as COVID-19.
It was a small study, reported in the New England Journal of Medicine, but showed that remdesivir, an unapproved drug that was originally developed to fight Ebola, helped 68% of patients with severe breathing problems due to COVID-19 to improve; 60% of those who relied on a ventilator to breathe and took the drug were able to wean themselves off the machines after 18...
Source: TIME: Health - April 14, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news
All Your Coronavirus Questions, Answered
One of the worst symptoms of any plague is uncertainty—who it will strike, when it will end, why it began. Merely understanding a pandemic does not stop it, but an informed public can help curb its impact and slow its spread. It can also provide a certain ease of mind in a decidedly uneasy time. Here are some of the most frequently asked questions about the COVID-19 pandemic from TIME’s readers, along with the best and most current answers science can provide.
A note about our sourcing: While there are many, many studies underway investigating COVID-19 and SARS-CoV-19, the novel coronavirus that causes the illn...
Source: TIME: Health - April 14, 2020 Category: Consumer Health News Authors: TIME Staff Tags: Uncategorized COVID-19 Explainer Source Type: news
Olfactory dysfunction from acute upper respiratory infections: relationship to season of onset
ConclusionThis study shows that seasonal variations occur in both the prevalence and magnitude of PVOD ‐related olfactory deficits in a North American population, and that such variations differ between NI‐PVOD and I‐PVOD cases. The findings suggest multiple viruses are involved in producing PVOD‐related olfactory deficits.
Source: International Forum of Allergy and Rhinology - April 12, 2020 Category: Allergy & Immunology Authors: Mark R. Potter,
Jonathan H. Chen,
Nina ‐Simone Lobban,
Richard L. Doty Tags: ORIGINAL ARTICLE Source Type: research
