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Total 34 results found since Jan 2013.

Doctors have long considered the thymus expendable. But could removing it be fatal?
The thymus, a butterfly-shaped organ that sits between our collarbones, has never seemed like a particularly useful appendage—at least in adults. During early childhood, it provides a place for T cells (the T stands for thymus) to mature into immune cells that attack invaders. But during adolescence the organ begins to shrink and mostly stops producing these cells. By adulthood, it’s assumed to be so useless that cardiac surgeons will occasionally remove it just to get easier access to the heart. But researchers have recently started to question that assumption, and a study published today in The New England Jo...
Source: ScienceNOW - August 2, 2023 Category: Science Source Type: news

The Conspirituality of Robert F. Kennedy Jr.
This article has been adapted from Chapter 23 of Conspirituality: How New Age Conspiracy Theories Became a Health Threat by Derek Beres, Matthew Remski, and Julian Walker. Copyright © 2023. Available from PublicAffairs, an imprint of Hachette Book Group, Inc.
Source: TIME: Health - July 5, 2023 Category: Consumer Health News Authors: Derek Beres, Matthew Remski, and Julian Walker Tags: Uncategorized freelance politics Source Type: news

Emerging field of evolutionary medicine could address range of health conditions
Key takeawaysScientists in the emerging field of evolutionary medicine are applying insights from ecology and evolution to inform research on biomedicine, public health and clinical care.Lessons from evolutionary medicine could help point toward treatments and preventive health measures for a range of diseases that otherwise have been difficult to address.The approach could also be useful in the quests to overcome antibiotic-resistant bacteria and chemotherapy-resistant cancers.Evolution has helped many members of the animal kingdom adapt to overcome or resist a range of medical issues that scientists are trying to solve i...
Source: UCLA Newsroom: Health Sciences - February 28, 2023 Category: Universities & Medical Training Source Type: news

FLEXiGUT: Rationale for exposomics associations with chronic low-grade gut inflammation
Environ Int. 2021 Oct 1;158:106906. doi: 10.1016/j.envint.2021.106906. Online ahead of print.ABSTRACTFLEXiGUT is the first large-scale exposomics study focused on chronic low-grade inflammation. It aims to characterize human life course environmental exposure to assess and validate its impact on gut inflammation and related biological processes and diseases. The cumulative influences of environmental and food contaminants throughout the lifespan on certain biological responses related to chronic gut inflammation will be investigated in two Flemish prospective cohorts, namely the "ENVIRONAGE birth cohort", which provides fo...
Source: Environment International - October 4, 2021 Category: Environmental Health Authors: Roger Pero-Gascon Lieselot Y Hemeryck Giulia Poma Gwen Falony Tim S Nawrot Jeroen Raes Lynn Vanhaecke Marthe De Boevre Adrian Covaci Sarah De Saeger Source Type: research

A Comprehensive Review on Natural Bioactive Compounds and Probiotics as Potential Therapeutics in Food Allergy Treatment
Food allergy is rising at an alarming rate and is a major public health concern. Globally, food allergy affects over 500 million people, often starting in early childhood and increasingly reported in adults. Commercially, only one approved oral immunotherapy-based treatment is currently available and other allergen-based immunotherapeutic are being investigated in clinical studies. As an alternative approach, a substantial amount of research has been conducted on natural compounds and probiotics, focusing on the immune modes of action, and therapeutic uses of such sources to tackle various immune-related diseases. Food all...
Source: Frontiers in Immunology - May 21, 2020 Category: Allergy & Immunology Source Type: research

Sex Differences in IL-33-Induced STAT6-Dependent Type 2 Airway Inflammation
In this study, we have demonstrated that delivery of OVA+IL-33 to the lungs of mice induced an innate inflammatory response that exhibited sex-dependent differences in magnitude and regulation. Compared to males, female mice produced larger amounts of type 2 cytokines and chemokines and had substantially more activated eosinophils and AAM in the lung; each of these responses was significantly lower in female mice lacking STAT6. On the contrary, male mice displayed less inflammation overall, and in some instances, no apparent role for STAT6 was observed. BALF levels of inflammatory mediators and eosinophils were very lo...
Source: Frontiers in Immunology - April 30, 2019 Category: Allergy & Immunology Source Type: research

Editorial: Shaping of Human Immune System and Metabolic Processes by Viruses and Microorganisms
Conclusions In conclusion, articles in this Research Topic made a very significant contribution to our understanding of the role played by environmental factors, dysbiotic conditions, and infections in triggering diseases. Since this is a rapidly expanding area of research, many other factors contributing to the onset of these diseases are not covered here. We are confident, however, that further studies will expand the list as well as bring a better understanding of mechanisms involved in the onset of autoimmune and autoinflammatory diseases. Author Contributions All authors listed have made a substantial, direct and i...
Source: Frontiers in Microbiology - April 16, 2019 Category: Microbiology Source Type: research

The Gut-Immune-Brain Axis in Autism Spectrum Disorders; A Focus on Amino Acids
Conclusion In Table 1, an overview is presented of the complex roles of AAs described in this review regarding the microbiome-gut-immune-brain axis in ASD. Besides behavioral deficits, people with ASD are characterized by systemic inflammation, gastrointestinal immune-related disturbances and changes in the gut microbiota composition. Moreover, differences in levels of specific AAs in various body compartments, including the intestinal tract, blood, urine and brain have been reported in patients with ASD, as well as in rodent models for ASD. This review described that specific AAs can modulate the intestinal epithelial im...
Source: Frontiers in Endocrinology - April 15, 2019 Category: Endocrinology Source Type: research

Evaluation of prooxidant-antioxidant balance in in vitro fertilization-conceived mice.
Conclusion: Since free radicals contribute to several pathological conditions and antioxidants play an important protective role against oxidative stress, evaluating the oxidant-antioxidant balance is very important. Although the results of this study showed that the quality of the defense mechanism against free radicals was not significantly different between the IVF-conceived and naturally conceived mice, other parameters of metabolic dysfunction need to be measured. PMID: 29984208 [PubMed]
Source: Clinical and Experimental Reproductive Medicine - July 11, 2018 Category: Reproduction Medicine Tags: Clin Exp Reprod Med Source Type: research

This Type of Non-Dairy Milk is the Healthiest, Study Says
That almond milk latte may be delicious, but a study just published in the Journal of Food Science and Technology suggests that the trendy beverage also has some drawbacks. When researchers compared the nutritional profiles of four popular “alternative” milks, they found that soy milk came out on top—and that almond, rice and coconut “milks” all lacked essential nutrients important for overall health. Plant-based “milks” are often marketed as wholesome and appropriate substitutes for the real thing. To find out if these claims measured up, scientists at McGill University in Canada ...
Source: TIME: Health - January 30, 2018 Category: Consumer Health News Authors: Amanda MacMillan Tags: Uncategorized almond milk almond milk calories almond milk nutrition coconut milk Diet/Nutrition healthytime is soy milk fattening Lactose Intolerance onetime soy milk calories soy milk nutrition soy milk vs milk Source Type: news

Residential Air Pollution and Associations with Wheeze and Shortness of Breath in Adults: A Combined Analysis of Cross-Sectional Data from Two Large European Cohorts
Conclusion: Exposure to PM and NO2 air pollution was associated with the prevalence of wheeze and shortness of breath in this large study, with stronger associations between PM2.5 and both outcomes among lower- versus higher-income participants. https://doi.org/10.1289/EHP1353 Received: 13 November 2016 Revised: 10 August 2017 Accepted: 14 August 2017 Published: 29 September 2017 Address correspondence to D. Doiron, Research Institute of the McGill University Health Centre, 2155 rue Guy, office 458, Montreal, Canada, H3H 2R9. Telephone: 1-514-934-1934 (ex. 71688). Email: ddoiron@maelstrom-research.org Supplemental Ma...
Source: EHP Research - September 29, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Maternal Exposure of BALB/c Mice to Indoor NO2 and Allergic Asthma Syndrome in Offspring at Adulthood with Evaluation of DNA Methylation Associated Th2 Polarization
Conclusions: Maternal exposure to indoor environmental NO2 causes allergic asthma-related consequences in offspring absent any subsequent lung provocation and potentiates the symptoms of allergic asthma in adult offspring following postnatal allergic sensitization and challenge; this response is associated with the Th2-based immune response and DNA methylation of the IL4 gene. https://doi.org/10.1289/EHP685 Received: 19 June 2016 Revised: 07 June 2017 Accepted: 19 June 2017 Published: 13 September 2017 Address correspondence to N. Sang, College of Environment and Resource, Shanxi University, Taiyuan, Shanxi 030006, P...
Source: EHP Research - September 13, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Cochrane Skin Group celebrate 20 years of improving treatment of skin diseases
World-leading dermatologists and their patients are celebrating huge improvements in the treatment of skin diseases like skin cancer, psoriasis, and acne as theCochrane Skin Group marks its 20th anniversary this week.   The effects of the 120 plus published Cochrane Skin Reviews have been far-reaching and have had real impacts on patient care. These include skin cancer, skin allergies, and acne, blistering diseases, hair disorders like alopecia, fungal infections and psoriasis as well as tropical parasitic disea ses.The group is coordinated by the University of Nottingham ’s Centre of Evidence Based Dermatology and is p...
Source: Cochrane News and Events - September 12, 2017 Category: Information Technology Authors: Muriah Umoquit Source Type: news