This page shows you your search results in order of date.

Order by Relevance | Date

Total 12401 results found since Jan 2013.

Classroom-Based Strategies to Reduce Disparities in Physical Activity Among Children with Asthma
AbstractChildren with asthma often experience physical activity (PA) induced symptoms 5 –15 min following the start of exercise. Classroom PA breaks provide short intermittent bouts of PA and may represent a novel strategy to safely promote PA participation in this clinical population. The purpose of this study was to determine the feasibility of a classroom-based PA intervention, I nterrupting Prolonged Sitting with Activity (InPACT), where teachers implement 5 × 4-min moderate-to-vigorous physical activity (MVPA) breaks throughout the school day. Nine classrooms at one elementary-middle school in Detroit, MI (stu...
Source: Prevention Science - January 26, 2022 Category: Psychiatry & Psychology Source Type: research

Synthesis and evaluation of new potential anti-pseudo-allergic agents
Bioorg Med Chem Lett. 2022 Jan 19:128575. doi: 10.1016/j.bmcl.2022.128575. Online ahead of print.ABSTRACTPseudo-allergic reactions frequently occur following clinical drug use and sometimes even cause mortal danger. Mas-related G-protein-coupled receptor member X2 (MRGPRX2) is a novel receptor that mediates pseudo-allergy and is an important target in the treatment of allergies. However, to date, there are no synthetic small-molecule inhibitors that prevent anaphylactoid reactions through this pathway. Our preliminary research suggested that B10-S and mubritinib effectively inhibited LAD2 cells. Therefore, two novel deriva...
Source: Bioorganic and Medicinal Chemistry Letters - January 22, 2022 Category: Chemistry Authors: Jiayu Lu Xiangjun Wang Shuai Ge Yajing Hou Yuexin Lv Huaizhen He Cheng Wang Source Type: research

UAMS Researcher: Early Treatment Could Tame Peanut Allergies in Small Kids
Dr. Stacie Jones co-authored the study, which includes patients from Arkansas Children's Hospital.
Source: Arkansas Business - Health Care - January 21, 2022 Category: American Health Source Type: news

Children can get over peanut allergies by slowly increasing their exposure, study suggests
US researchers found nearly three quarters of children with the allergy given immunotherapy avoided a reaction when given the equivalent of 16 peanuts after two-and-a-half years.
Source: the Mail online | Health - January 20, 2022 Category: Consumer Health News Source Type: news

Early treatment could tame peanut allergies in small kids
A new study finds that young children might be able to overcome their peanut allergies if treated early enough
Source: ABC News: Health - January 20, 2022 Category: Consumer Health News Tags: Health Source Type: news

Study: Starting peanut immunotherapy at age 3 or younger can resolve allergies
Most young children with peanut allergies treated with immunotherapy achieved desensitization within 2 1/2 years, a study published Thursday by the Lancet found.
Source: Health News - UPI.com - January 20, 2022 Category: Consumer Health News Source Type: news

The association of HLA-G polymorphism with oral and genital HPV infection in men
AbstractThe host genetic factors that influence the natural history of human papillomavirus (HPV) infection in men are not well known. Our aim was to evaluate the role of human leukocyte antigen (HLA)-G polymorphism in oral and genital HPV infection in men. Altogether, 130 men from the Finnish Family HPV Study, with a 6-year follow-up, were included in the analyses. HLA-G alleles were tested by direct sequencing. Oral, urethral, and semen samples were collected and analyzed for 24 different HPV genotypes. Unconditional logistic regression was used to determine associations between HLA-G alleles and genotypes with HPV infec...
Source: European Journal of Clinical Microbiology and Infectious Diseases - January 20, 2022 Category: Microbiology Source Type: research

Autism Spectrum Disorder Initiation by Inflammation-Facilitated Neurotoxin Transport
Neurochem Res. 2022 Jan 20. doi: 10.1007/s11064-022-03527-x. Online ahead of print.ABSTRACTAutism spectrum disorders have been linked to genetics, gut microbiota dysbiosis (gut dysbiosis), neurotoxin exposures, maternal allergies or autoimmune diseases. Two barriers to ingested neurotoxin transport into the central nervous system of a fetus or child are the gastrointestinal wall of the mother or child and the blood-brain barrier of the fetus or child. Inflammation from gut dysbiosis or inflammation from a disease or other agent can increase the gastrointestinal wall and the blood-brain barrier permeabilities to enable neur...
Source: Neurochemical Research - January 20, 2022 Category: Neuroscience Authors: Kevin Roe Source Type: research

Phthalates mixture on allergies and oxidative stress biomarkers among children: The Hokkaido study
CONCLUSION: Mixture of phthalate metabolites were associated with wheeze and eczema. The main contributors to the association were DEHP and DINP metabolites. No mediation of oxidative stress was observed.PMID:35051840 | DOI:10.1016/j.envint.2022.107083
Source: Environment International - January 20, 2022 Category: Environmental Health Authors: Rahel Mesfin Ketema Yu Ait Bamai Chihiro Miyashita Takeshi Saito Reiko Kishi Atsuko Ikeda-Araki Source Type: research

Autism Spectrum Disorder Initiation by Inflammation-Facilitated Neurotoxin Transport
Neurochem Res. 2022 Jan 20. doi: 10.1007/s11064-022-03527-x. Online ahead of print.ABSTRACTAutism spectrum disorders have been linked to genetics, gut microbiota dysbiosis (gut dysbiosis), neurotoxin exposures, maternal allergies or autoimmune diseases. Two barriers to ingested neurotoxin transport into the central nervous system of a fetus or child are the gastrointestinal wall of the mother or child and the blood-brain barrier of the fetus or child. Inflammation from gut dysbiosis or inflammation from a disease or other agent can increase the gastrointestinal wall and the blood-brain barrier permeabilities to enable neur...
Source: Neurochemical Research - January 20, 2022 Category: Neuroscience Authors: Kevin Roe Source Type: research

Food protein enterocolitis syndrome: underdiagnosed, not treated optimally
Food protein enterocolitis syndrome (FPIES) is an uncommon—and often under-recognised—type of food allergy, which generally presents in the first year of life, with tendency for remission in early childhood (although adults may also be affected, with increasing reports of adult FPIES appearing in the literature).1 In contrast to most infant food allergies, FPIES is not IgE-mediated and does not present with ‘typical’ IgE symptoms of skin pruritus and or features of anaphylaxis. Rather, it is characterised by onset of profuse vomiting, typically within 1–3 hours after ingestion of the trigger f...
Source: Archives of Disease in Childhood - January 20, 2022 Category: Pediatrics Authors: Campbell, D. E., Turner, P. J. Tags: Editorial Source Type: research

The association of allergic asthma and carotid intima-media thickness in adolescence: data of the prospective early vascular ageing (EVA)-Tyrol cohort study
CONCLUSION: Allergic asthma in the youth is associated with an increased carotid intima-media thickness. Physicians should therefore be aware of allergic asthma as a potential cardiovascular risk factor in children and adolescents. Trial Registration Number The EVA-Tyrol Study has been retrospectively registered at clinicaltrials.gov under NCT03929692 since April 29, 2019.PMID:35042472 | DOI:10.1186/s12872-021-02452-1
Source: Atherosclerosis - January 19, 2022 Category: Cardiology Authors: Bernhard Winder Sophia J Kiechl Nadja M Gruber Beno ît Bernar Nina Gande Anna Staudt Katharina Stock Christoph Hochmayr Ralf Geiger Andrea Griesmacher Markus Anliker Stefan Kiechl Ursula Kiechl-Kohlendorfer Michael Knoflach Early Vascular Ageing (EVA)-Ty Source Type: research

COVID-19 scenario and recommendations on the continuity of immunobiological therapy in patients with atopic asthma in Brazil and Latin America
Expert Rev Respir Med. 2022 Jan 17. doi: 10.1080/17476348.2022.2027758. Online ahead of print.ABSTRACTINTRODUCTION: With the abrupt establishment of the COVID-19 pandemic, treatment for immunological diseases may be influenced by the SARS-CoV-2 infection, including asthma and other allergies. Immunobiologics play a pivotal role in the management of severe symptoms of allergy and an opinion regarding the continuity of this treatment during the COVID-19 pandemic must be issued.AREAS COVERED: In Brazil and other countries, patients with severe asthma were included in the priority groups for COVID-19 vaccination, even those wh...
Source: Expert Review of Respiratory Medicine - January 17, 2022 Category: Respiratory Medicine Authors: Rafael de Oliveira Resende Vin ícius José de Oliveira Alessandro Sousa Correa Pedro Trica de Ara újo Ernesto Akio Taketomi Source Type: research

Early peanut introduction wins over the HLA-DQA1*01:02 allele in the interplay between environment and genetics
The rising incidence of food allergy in children underscores the importance of environmental exposures; however, genetic factors play a major role. How the environment and genetics interact to cause food allergy remains unclear. The landmark Learning Early About Peanut Allergy (LEAP) clinical trial established that early peanut introduction protects high-risk infants, consistent with the tolerizing effects of gut exposure. In this issue of the JCI, Kanchan et al. leveraged the LEAP trial data to examine molecular genetic mechanisms of early sensitization. A previously identified HLA risk allele for peanut allergy (DQA1*01:...
Source: Journal of Clinical Investigation - January 16, 2022 Category: Biomedical Science Authors: Monali Manohar, Kari Christine Nadeau, Maya Kasowski Source Type: research