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Total 38317 results found since Jan 2013.

Multi-element Exposure and Cognitive Function in Rural Elderly Chinese
Biol Trace Elem Res. 2023 Sep 16. doi: 10.1007/s12011-023-03774-1. Online ahead of print.ABSTRACTTo investigate the relationship between selenium (Se) based multi-element combined exposure and cognitive function in rural elderly individuals, a cross-sectional study was conducted. The study involved 416 older adults aged 60 and above, residing in four different areas of Enshi county, China, with varying soil Se levels. Inductively coupled plasma mass spectrometry (ICP-MS) was employed to measure the concentrations of Se, copper (Cu), iron (Fe), zinc (Zn), calcium (Ca), magnesium (Mg), cadmium (Cd), arsenic (As), and lead (P...
Source: Biological Trace Element Research - September 16, 2023 Category: Biology Authors: Lidan Duan Liqin Su Xiaohong He Yegang Du Yanying Duan Ning Xu Rangpeng Wu Yunfeng Zhu Ranqi Shao Frederick W Unverzagt Ann M Hake Yinlong Jin Sujuan Gao Source Type: research

Cold atmospheric plasma fumigation suppresses postharvest apple Botrytis cinerea by triggering intracellular reactive oxygen species and mitochondrial calcium
In this study, the effects of cold atmospheric plasma (CAP) fumigation on apple B. cinerea under different exposure times and intensities were investigated. The growth of B. cinerea in vitro and in vivo was significantly suppressed by the CAP fumigation at least 700 μL/L for 5 min. To reveal the possible mechanism of antifungal activity of CAP fumigation, the pathogen was exposed to 700 μL/L and 1000 μL/L for 5 min, respectively. The results indicated that the CAP-treated spores of the pathogen underwent shrinkage, cell membrane collapse and cytoplasmic vacuolation. The results obtained from the fluorescent probe assay ...
Source: International Journal of Food Microbiology - September 16, 2023 Category: Food Science Authors: Jiankang Cao Qiong Fang Chenrui Han Chongshan Zhong Source Type: research

Deciphering calcium signals in cells and tissues with tailored probes and models
J Physiol. 2023 Sep 16. doi: 10.1113/JP285037. Online ahead of print.NO ABSTRACTPMID:37715737 | DOI:10.1113/JP285037
Source: The Journal of Physiology - September 16, 2023 Category: Physiology Authors: Nicolas Demaurex Source Type: research

Prevalence and predictors of vitamin D deficiency among adults with epilepsy: A cross-sectional study
CONCLUSION: Vitamin D deficiency among PWE is prevalent in our local population, suggesting that regular screening should be considered for those at risk. Early identification would allow intervention to reduce the risk of future complications.PMID:37716324 | DOI:10.1016/j.yebeh.2023.109432
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Ching Soong Khoo Mohd Fadzli Shukor Juen Kiem Tan Michelle Maryanne Tan Li Ling Yong Siti Zaleha Sahibulddin Siti Hajar Mat Desa Norasyikin A Wahab Rozita Hod Hui Jan Tan Source Type: research

Channeling hope for uranium-induced kidney damage and beyond with TRPML1
Cell Calcium. 2023 Sep 11;115:102799. doi: 10.1016/j.ceca.2023.102799. Online ahead of print.NO ABSTRACTPMID:37716038 | DOI:10.1016/j.ceca.2023.102799
Source: Cell Calcium - September 16, 2023 Category: Cytology Authors: Kirill Kiselyov Source Type: research

Cholesterol homeostasis, mechanisms of molecular pathways, and cardiac health: a current outlook
Curr Probl Cardiol. 2023 Sep 14:102081. doi: 10.1016/j.cpcardiol.2023.102081. Online ahead of print.ABSTRACTThe metabolism of lipoproteins, which regulates the transit of the lipid to and from tissues, is crucial to maintaining cholesterol homeostasis. Cardiac remodeling is referred to as a set of molecular, cellular, and interstitial changes that, following injury, affect the size, shape, function, mass, and geometry of the heart. Acetyl coenzyme A (acetyl CoA), which can be made from glucose, amino acids, or fatty acids, is the precursor for the synthesis of cholesterol. In this article, authors explain concepts behind c...
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Rajiv Kumar Neelam Chhillar Dhruv Sanjay Gupta Ginpreet Kaur Shailey Singhal Tanya Chauhan Source Type: research

Study on the correlation and interaction between metals and dyslipidemia: a case-control study in Chinese community-dwelling elderly
Environ Sci Pollut Res Int. 2023 Sep 16. doi: 10.1007/s11356-023-29695-z. Online ahead of print.ABSTRACTPrevious studies on the association between metals and dyslipidemia are not completely consistent. There are few studies investigating the relationship between mixed metal exposure and dyslipidemia as well as the effects of metals on dyslipidemia in community-dwelling elderly. To evaluate the correlations and interaction effect between the urinary concentrations of metals and the risk of dyslipidemia in community-dwelling elderly. We designed a case-control study to assess the correlation between urine metals and dyslipi...
Source: Environmental Science and Pollution Research International - September 16, 2023 Category: Environmental Health Authors: Zhongyuan Zhang Rui Wang Pei He Yuqing Dai Siyu Duan Meiyan Li Zhuoheng Shen Xiaoyu Li Jian Sun Source Type: research

Deciphering calcium signals in cells and tissues with tailored probes and models
J Physiol. 2023 Sep 16. doi: 10.1113/JP285037. Online ahead of print.NO ABSTRACTPMID:37715737 | DOI:10.1113/JP285037
Source: The Journal of Physiology - September 16, 2023 Category: Physiology Authors: Nicolas Demaurex Source Type: research

Age-related changes in P2Y receptor signalling in mouse cochlear supporting cells
J Physiol. 2023 Sep 16. doi: 10.1113/JP284980. Online ahead of print.ABSTRACTOur sense of hearing depends on the function of a specialised class of sensory cells, the hair cells, which are found in the organ of Corti of the mammalian cochlea. The unique physiological environment in which these cells operate is maintained by a syncitium of non-sensory supporting cells, which are crucial for regulating cochlear physiology and metabolic homeostasis. Despite their importance for cochlear function, the role of these supporting cells in age-related hearing loss, the most common sensory deficit in the elderly, is poorly understoo...
Source: The Journal of Physiology - September 16, 2023 Category: Physiology Authors: Sarah A Hool Jing-Yi Jeng Daniel J Jagger Walter Marcotti Federico Ceriani Source Type: research

Contribution and therapeutic value of mitophagy in cerebral ischemia-reperfusion injury after cardiac arrest
Biomed Pharmacother. 2023 Sep 14;167:115492. doi: 10.1016/j.biopha.2023.115492. Online ahead of print.ABSTRACTCardiopulmonary resuscitation and related life support technologies have improved substantially in recent years; however, mortality and disability rates from cardiac arrest (CA) remain high and are closely associated with the high incidence of cerebral ischemia-reperfusion injury (CIRI), which is explained by a "double-hit" model (i.e., resulting from both ischemia and reperfusion). Mitochondria are important power plants in the cell and participate in various biochemical processes, such as cell differentiation and...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 16, 2023 Category: Drugs & Pharmacology Authors: Zheng Li Jihong Xing Source Type: research

Inhibition of mitochondrial calcium uptake by Ru360 enhances the effect of 1800  MHz radio-frequency electromagnetic fields on DNA damage
In conclusion, our results indicated that inhibiting MCU increases the genotoxicity of RF-EMF exposure, and more attention needs to be paid to the possible health impact of RF-EMF exposure under these treatments.PMID:37716072 | DOI:10.1016/j.ecoenv.2023.115472
Source: Ecotoxicology and Environmental Safety - September 16, 2023 Category: Environmental Health Authors: Chuan Sun Longtao Zhu Houbing Qin Huili Su Jing Zhang Sanying Wang Xiaogang Xu Zhenlei Zhao Genxiang Mao Jun Chen Source Type: research

Orbitofrontal cortex conveys stimulus and task information to the auditory cortex
Curr Biol. 2023 Sep 12:S0960-9822(23)01139-9. doi: 10.1016/j.cub.2023.08.059. Online ahead of print.ABSTRACTAuditory cortical neurons modify their response profiles in response to numerous external factors. During task performance, changes in primary auditory cortex (A1) responses are thought to be driven by top-down inputs from the orbitofrontal cortex (OFC), which may lead to response modification on a trial-by-trial basis. While OFC neurons respond to auditory stimuli and project to A1, the function of OFC projections to A1 during auditory tasks is unknown. Here, we observed the activity of putative OFC terminals in A1 ...
Source: Current Biology - September 16, 2023 Category: Biology Authors: Jonah K Mittelstadt Patrick O Kanold Source Type: research