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Overcoming the Challenges in the Development and Implementation of Artificial Intelligence in Radiology: A Comprehensive Review of Solutions Beyond Supervised Learning
Korean J Radiol. 2023 Aug 28. doi: 10.3348/kjr.2023.0393. Online ahead of print.ABSTRACTArtificial intelligence (AI) in radiology is a rapidly developing field with several prospective clinical studies demonstrating its benefits in clinical practice. In 2022, the Korean Society of Radiology held a forum to discuss the challenges and drawbacks in AI development and implementation. Various barriers hinder the successful application and widespread adoption of AI in radiology, such as limited annotated data, data privacy and security, data heterogeneity, imbalanced data, model interpretability, overfitting, and integration wit...
Source: Korean J Radiol - September 19, 2023 Category: Radiology Authors: Gil-Sun Hong Miso Jang Sunggu Kyung Kyungjin Cho Jiheon Jeong Grace Yoojin Lee Keewon Shin Ki Duk Kim Seung Min Ryu Joon Beom Seo Sang Min Lee Namkug Kim Source Type: research
Evaluating Prognostic Value of Dynamics of Circulating Lactate Dehydrogenase in Colorectal Cancer Using Modeling and Machine Learning
Clin Pharmacol Ther. 2023 Sep 19. doi: 10.1002/cpt.3052. Online ahead of print.ABSTRACTPre-treatment serum lactate dehydrogenase (LDH) levels have been associated with poor prognosis in several types of cancer, including metastatic colorectal cancer (mCRC). However, very few models link survival to longitudinal LDH measured repeatedly over time during treatment. We investigated the prognostic value of on-treatment LDH dynamics in mCRC. Using data from two large Phase III studies (2L and 3L+ mCRC settings, n = 824 and 210, respectively), we found that integrating longitudinal LDH data with baseline risk factors significantl...
Source: Clinical Pharmacology and Therapeutics - September 19, 2023 Category: Drugs & Pharmacology Authors: Haolun Ding Min Yuan Yaning Yang Manish Gupta Xu Steven Xu Source Type: research
Linking Clinic With Classroom in Intensive Focused Preservice Education on Augmentative and Alternative Communication
CONCLUSION: This study suggests the significance of compulsory fieldwork embedded in the AAC training as evidenced by the graduate students' subjective perception of competence and preparedness in AAC services following the AAC course.PMID:37724941 | DOI:10.1044/2023_AJSLP-23-00020
Source: American Journal of Speech-Language Pathology - September 19, 2023 Category: Speech-Language Pathology Authors: Sojung Kim Yu-Kyong Choe Source Type: research
Acupuncture Improves Synaptic Plasticity of SAMP8 Mice through the RhoA/ROCK Pathway
CONCLUSION: Acupuncture can improve synaptic plasticity by inhibiting the abnormal activation of the RhoA/ROCK pathway, and improve the spatial learning and memory ability of AD, so as to achieve the purpose of treating AD.PMID:37723951 | DOI:10.2174/1567205020666230828095826
Source: Current Alzheimer Research - September 19, 2023 Category: Neurology Authors: Bohong Kan Zhengjia Dong Zhenyu Tang Lan Zhao Zhen Li Source Type: research
An Early Prediction Model for Estimating Bronchopulmonary Dysplasia in Preterm Infants
CONCLUSION: The postnatal day 7 model was the best predictor of BPD or death. Future validation studies will help identify infants who may benefit from preventive therapies and develop individualized care.PMID:37725910 | DOI:10.1159/000533299
Source: Neonatology - September 19, 2023 Category: Perinatology & Neonatology Authors: Yasemin Ezgi Kostekci Batuhan Bak ırarar Emel Okulu Omer Erdeve Begum Atasay Saadet Arsan Source Type: research
MicroRNA-411-3p motivates methotrexate's cellular uptake and cytotoxicity via targeting Yin-yang 1 in leukemia cells
This study aimed to figure out how microRNA (miR)-411-3p's impacts on methotrexate (MTX)'s cellular uptake and cytotoxicity in acute lymphoblastic leukaemia (ALL) CEM-C1 cells by targeting Yin-yang 1 (YY1). miR-411-3p and YY1 were detected by RT-qPCR or Western blot. Intracellular MTX concentration was measured by enzyme-linked immunosorbent assay. Cell viability and apoptosis were evaluated by CCK-8, clonal formation assay, and flow cytometry. Verification of miR-411-3p and YY1's targeting link was manifested. It came out that miR-411-3p mimic or si-YY1 elevated intracellular MTX, MTX-induced cytotoxicity and apoptosis ra...
Source: Acta Biochim Pol - September 19, 2023 Category: Biochemistry Authors: HuiJing Sun ShuGuang Zhou ZhouSheng Yang MingYu Meng Yan Dai XinYe Li XiaoYu Chen Source Type: research
Role of registered dietitians in nasoenteric feeding tube placement
Nutr Clin Pract. 2023 Sep 19. doi: 10.1002/ncp.11071. Online ahead of print.ABSTRACTProvision of enteral nutrition (EN) in hospitalized patients is an integral part of clinical care. For various reasons, including but not limited to delayed enteral access placement and EN initiation, it is becoming more prevalent for registered dietitians (RDs) to place feeding tubes in various clinical settings. Although numerous RDs have expanded their practice by learning this skill, many remain hesitant about adding feeding tube placement to their scope of responsibilities. Feeding tube placement is within RDs' scope of practice. The r...
Source: Nutrition in Clinical Practice - September 19, 2023 Category: Nutrition Authors: Maryam Yeganehjoo Jennifer Johanek Source Type: research
Reconsidering a Global Agency for Medical Education: Back to the Drawing Board?
This article proposes a more democratic and equitable means by which a global organization for medical education might choose its priority areas, and a more inclusive method by which it could engage the medical education community worldwide. It concludes by hypothesizing about the future of global representation and priority-setting, and outlines a series of principles that could form the basis for a reimagined agency that would have the potential to become a force for empowerment and global justice in medical education.PMID:37724805 | DOI:10.1080/10401334.2023.2259363
Source: Teaching and Learning in Medicine - September 19, 2023 Category: Universities & Medical Training Authors: Mohammed Ahmed Rashid Thirusha Naidu Dawit Wondimagegn Cynthia Whitehead Source Type: research
Point-of-care AI-assisted stepwise ultrasound pneumothorax diagnosis
Phys Med Biol. 2023 Sep 19. doi: 10.1088/1361-6560/acfb70. Online ahead of print.ABSTRACTUltrasound is extensively utilized as a convenient and costeffective method in emergency situations. Unfortunately, the limited availability of skilled clinicians in emergency hinders the wider adoption of point-of-care ultrasound. To overcome this challenge, this paper aims to aid less experienced healthcare providers in emergency lung ultrasound scans.
Approach: To assist healthcare providers, it is important to have a comprehensive model that can automatically guide the entire process of lung ultrasound based on the clinicia...
Source: Physics in Medicine and Biology - September 19, 2023 Category: Physics Authors: Kyungsang Kim Fabiola Macruz Dufan Wu Christopher Bridge Suzannah McKinney Ahad Alhassan Al Saud Elshaimaa Sharaf Adam Pely Paul Danset Tom Duffy Davin Dhatt Varun Buch Andrew Liteplo Quanzheng Li Source Type: research
Efficacy of a music-based intervention in a preclinical model of traumatic brain injury: An initial foray into a novel and non-pharmacological rehabilitative therapy
Exp Neurol. 2023 Sep 17:114544. doi: 10.1016/j.expneurol.2023.114544. Online ahead of print.ABSTRACTTraumatic brain injury (TBI) causes neurobehavioral and cognitive impairments that negatively impact life quality for millions of individuals. Because of its pernicious effects, numerous pharmacological interventions have been evaluated to attenuate the TBI-induced deficits or to reinstate function. While many such pharmacotherapies have conferred benefits in the laboratory, successful translation to the clinic has yet to be achieved. Given the individual, medical, and societal burden of TBI, there is an urgent need for alte...
Source: Experimental Neurology - September 19, 2023 Category: Neurology Authors: Eleni H Moschonas Tyler S Ranellone Vincent J Vozzella Piper L Rennerfeldt Corina O Bondi Ellen M Annas Rachel A Bittner Dana M Tamura Rithika I Reddy Rithik R Eleti Jeffrey P Cheng Jessica M Jarvis Ericka L Fink Anthony E Kline Source Type: research
Aortic Annulus Detection Based on Deep Learning for Transcatheter Aortic Valve Replacement Using Cardiac Computed Tomography
CONCLUSION: Our deep learning framework was feasible to detect the 3D complex structure of the aortic annulus plane using cardiac CT for TAVR. The performance of our algorithms was higher than other convolutional neural networks.PMID:37724499 | PMC:PMC10506901 | DOI:10.3346/jkms.2023.38.e306
Source: J Korean Med Sci - September 19, 2023 Category: General Medicine Authors: Yongwon Cho Soojung Park Sung Ho Hwang Minseok Ko Do-Sun Lim Cheol Woong Yu Seong-Mi Park Mi-Na Kim Yu-Whan Oh Guang Yang Source Type: research
Measuring Clinical Preparedness After Residency Training: Development of a New Instrument
CONCLUSIONS: To learn about the possible impact of length of training, we developed a novel approach to assess preparedness for independent clinical practice of family medicine residency graduates.PMID:37725776 | DOI:10.22454/FamMed.2023.973082
Source: Famly Medicine - September 19, 2023 Category: Primary Care Authors: Patricia A Carney Annie Ericson Colleen Conry James C Martin Alan B Douglass M Patrice Eiff Source Type: research
Resident Involvement in Curricular and Clinical Practice Change and Satisfaction With Training According to Length of Training in Family Medicine
CONCLUSIONS: Four-year residents were involved in a greater number of quality improvement projects and had a more diverse profile of involvement than those in 3-year residency programs. Involvement in practice and curricular change and the learning environment were associated with greater levels of resident satisfaction with training in both 3-year and 4-year programs.PMID:37725772 | DOI:10.22454/FamMed.2023.346131
Source: Famly Medicine - September 19, 2023 Category: Primary Care Authors: Jennifer Romeu Patricia A Carney Annie Ericson Nicholas Weida Jennifer Somers Bethany Picker Suki Tepperberg Richard A Young Source Type: research
Enhancing Medical Students' Understanding of Team-Based Care to Address Social Determinants of Health: A Case-Based Experience
CONCLUSIONS: Our students reported that a case-based experience coupled with a small-group debriefing was an effective method for teaching them how to use a team-based approach to address social determinants of health.PMID:37725770 | DOI:10.22454/FamMed.2023.914274
Source: Famly Medicine - September 19, 2023 Category: Primary Care Authors: Jennifer D Taylor Jalysa King Source Type: research
Assessing Educational and Attitudinal Outcomes of a Student Learner Experience Focused on Homelessness
CONCLUSIONS: Improvements from time point 1 to 2 demonstrated the value of didactic learning, while further improvements from time point 2 to 3 demonstrated the added benefit of hands-on experiential learning. Our study illustrates the potential educational benefits that a PNP provides to medical students who may encounter or care for this population during their careers.PMID:37725769 | DOI:10.22454/FamMed.2023.112960
Source: Famly Medicine - September 19, 2023 Category: Primary Care Authors: Drupad Annapureddy Shannon Teaw Pooja Kumar William M Turlington Ethan Wang Shelley Speed Nora Gimpel Source Type: research
