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First Author Highlights
Am J Physiol Renal Physiol. 2023 Oct 1;325(4):i-ii. doi: 10.1152/ajprenal.2023.325.4.AU.NO ABSTRACTPMID:37738000 | DOI:10.1152/ajprenal.2023.325.4.AU
Source: American Journal of Physiology. Renal Physiology - September 22, 2023 Category: Physiology Source Type: research
An exploration of ex-boarding school adults' attachment styles and substance use behaviours
Attach Hum Dev. 2023 Sep 22:1-15. doi: 10.1080/14616734.2023.2228761. Online ahead of print.ABSTRACTOur study examines the relationship between boarding school attendance, adult attachment styles, parental bonding, and substance use, aiming was to quantitatively investigate if caregiver deprivation caused by boarding contributes to enduring outcomes in adults. In a sample of 149 adults, measures included AUDIT and DUDIT (substance use), Parental Bonding Instrument (parental care), and Experiences in Close Relationships (adult attachment). Pearson's correlation revealed a significant negative association between age at firs...
Source: Attachment and Human Development - September 22, 2023 Category: Child Development Authors: Natalie Wharton Mariel Marcano-Olivier Source Type: research
Pharmacological inhibition of S6K1 rescues synaptic deficits and attenuates seizures and depression in chronic epileptic rats
CONCLUSION: In conclusion, our data suggest that inhibition of S6K1 attenuates seizures and depression in chronic epileptic rats via the rescue of synaptic structural and functional deficits. Given the wide range of physiological functions of mTOR, inhibition of its effective but relatively simple functional downstream molecules is a promising target for the development of drugs for epilepsy.PMID:37736829 | DOI:10.1111/cns.14475
Source: CNS Neuroscience and Therapeutics - September 22, 2023 Category: Neuroscience Authors: Yuying Zhang Xiaojuan Cheng Luyan Wu Juan Li Changyun Liu Mingjia Wei Chaofeng Zhu Huapin Huang Wanhui Lin Source Type: research
The prevalence and risk factors study of cognitive impairment: Analysis of the elderly population of Han nationality in Hunan province, China
CONCLUSION: A representative prevalence of cognitive impairment, MCI, and dementia was found in the elderly Han Chinese population in Southern China. And we further explored the role of known risk factors, particularly in physical activity, smoking, and alcohol consumption.PMID:37736696 | DOI:10.1111/cns.14478
Source: CNS Neuroscience and Therapeutics - September 22, 2023 Category: Neuroscience Authors: Tianyan Xu Guiwen Bu Li Yuan Lu Zhou Qijie Yang Yuan Zhu Sizhe Zhang Qianqian Liu Ziyu Ouyang Xuan Yang Beisha Tang Bin Jiao Yuzhang Bei Lu Shen Source Type: research
Melatonin regulates the circadian rhythm to ameliorate postoperative sleep disorder and neurobehavioral abnormalities in aged mice
CONCLUSIONS: Melatonin receptors in SCN, circadian rhythm, and ERK/CREB signaling pathway participate in the pathophysiological processes of PSD and delirium-like behavior. Melatonin intervention could be a potential preventative approach for PSD and delirium.PMID:37736695 | DOI:10.1111/cns.14436
Source: CNS Neuroscience and Therapeutics - September 22, 2023 Category: Neuroscience Authors: Xixi Jia Yanan Song Zhengqian Li Ning Yang Taotao Liu Dengyang Han Zhuonan Sun Chengmei Shi Yang Zhou Jie Shi Yajie Liu Xiangyang Guo Source Type: research
NcRNAs: A synergistically antiapoptosis therapeutic tool in Alzheimer's disease
CONCLUSIONS: This review provides a future diagnosis and treatment strategy for AD patients based on ncRNAs.PMID:37735992 | DOI:10.1111/cns.14476
Source: CNS Neuroscience and Therapeutics - September 22, 2023 Category: Neuroscience Authors: Liangxian Li Mingyue Jin Jie Tan Bo Xiao Source Type: research
Rasd1 is involved in white matter injury through neuron-oligodendrocyte communication after subarachnoid hemorrhage
CONCLUSIONS: It can be concluded that Rasd1 exerts a modulated role in oligodendrocytes ferroptosis in WMI following SAH.PMID:37735980 | DOI:10.1111/cns.14452
Source: CNS Neuroscience and Therapeutics - September 22, 2023 Category: Neuroscience Authors: Wenqiao Fu Xudong Che Jiahe Tan Shizhen Cui Yinrui Ma Daiqi Xu Haibo Long Xiaolin Yang Tangmin Wen Zhaohui He Source Type: research
Effects of Intra-Base Pair Proton Transfer on Dissociation and Singlet Oxygenation of 9-Methyl-8-Oxoguanine-1-Methyl-Cytosine Base-Pair Radical Cations
Chemphyschem. 2023 Sep 22:e202300511. doi: 10.1002/cphc.202300511. Online ahead of print.ABSTRACT8-Oxoguanosine is the most common oxidatively generated base damage and pairs with cytidine within duplex DNA. The 8-oxoguanosine-cytidine lesion, if not recognized and removed, not only leads to G-to-T transversion mutations but renders the base pair being more vulnerable to the ionizing radiation and singlet oxygen (1O2) damage. Herein, reaction dynamics of a prototype Watson-Crick base pair [9MOG·1MC]·+, consisting of 9-methyl-8-oxoguanine radical cation (9MOG·+) and 1-methylcystosine (1MC), was examined using mass spectr...
Source: Chemphyschem - September 22, 2023 Category: Chemistry Authors: May Myat Moe Midas Tsai Jianbo Liu Source Type: research
High-level ab initio evidence of bipyramidal Cu < sub > 5 < /sub > clusters as fluxional Jahn-Teller molecules
Chemphyschem. 2023 Sep 22:e202300637. doi: 10.1002/cphc.202300637. Online ahead of print.ABSTRACTThe front cover artwork is provided by María Pilar de Lara-Castells, Head of the AbinitFot Group at IFF-CSIC (Madrid), Coordinator of the National Project "COSYES", and Chair of the COST Action CA21101 "COSY", and Alexander O. Tereshchenko Mitrushchenkov from the University Gustave Eiffel (France). The image shows the connection between the Janh-Teller effect featured by bypiramidal Cu5 clusters and the property of fluxionality. Cover design by Katarzyna Krupka. Read the full text of the Research Article at 10.1002/cphc.202300...
Source: Chemphyschem - September 22, 2023 Category: Chemistry Authors: Akexander O Mitrushchenkov Mar ía Pilar de Lara-Castells Source Type: research
Prevalence and factors associated with multidimensional child deprivation: Findings from the Future of Families and Child Well-Being Study
This study examines multidimensional child deprivation using eight dimensions and twelve indicators based on the Convention on the Rights of the Child (CRC). Using a sample of children at age nine from the fifth wave of the Future of Families and Child Well-being Study, this study applied the multiple overlapping deprivation analysis (MODA), a comprehensive analytic method to assess the multidimensionality of child deprivation and to provide a detailed picture of material and social forms of deprivation among the U.S. children. This study found that the overall child deprivation rate was 8.89%; environmental safety (20.36%...
Source: Children and Youth Services Review - September 22, 2023 Category: Child Development Authors: Jihyun Oh Source Type: research
Sleep Spindle Generation Before and After Epilepsy Surgery: A Source Imaging Study in Children with Drug-Resistant Epilepsy
CONCLUSIONS: Our data indicate alterations in the EEG slow spindles after resective epilepsy surgery. Fast spindle generation on the contrary did not change after surgery. Although the study is limited by its retrospective nature, lack of healthy controls, and reduced cortical spatial sampling, our findings suggest a spatial relationship between the slow spindles and the epileptogenic generators.PMID:37737957 | DOI:10.1007/s10548-023-01007-1
Source: Brain Topography - September 22, 2023 Category: Neuroscience Authors: Assia Chericoni Lorenzo Ricci Georgios Ntolkeras Roberto Billardello Scellig S D Stone Joseph R Madsen Christos Papadelis P Ellen Grant Phillip L Pearl Fabrizio Taffoni Alexander Rotenberg Eleonora Tamilia Source Type: research
Effects of < em > Aeriscardovia aeriphila < /em > on growth performance, antioxidant functions, immune responses, and gut microbiota in broiler chickens
In conclusion, oral administration of A. aeriphila could improve the growth performance, serum antioxidant capacity, immune modulation, and gut health of broilers. Our findings may provide important information for the application of A. aeriphila in poultry production.PMID:37735944 | DOI:10.1631/jzus.B2200621
Source: J Zhejiang Univ Sci ... - September 22, 2023 Category: Science Authors: Muhammad Zahid Farooq Xinkai Wang Xianghua Yan Source Type: research
Rapid Detection of bla < sub > KPC < /sub > in Carbapenem-Resistant Enterobacterales Based on CRISPR/Cas13a
In conclusion, the RPA-Cas13a system is a simple and one-hour efficient technology for the detection of a potentially fatal antibiotic resistance gene.PMID:37737960 | DOI:10.1007/s00284-023-03457-z
Source: Current Microbiology - September 22, 2023 Category: Microbiology Authors: Mingjun Liang Bin Xiao Lidan Chen Xiaoyan Huang Jinchao Li Zhenzhan Kuang Xinping Chen Xiuna Huang Zhaohui Sun Linhai Li Source Type: research
Rapid and Specific Detection of B. melitensis Targeting BMEI1661 Gene Using Loop-mediated Isothermal Amplification (LAMP) Combined With Lateral Flow immunoassay (LFIA)
Curr Microbiol. 2023 Sep 22;80(11):351. doi: 10.1007/s00284-023-03463-1.ABSTRACTB. melitensis is the most pathogenic zoonotic species of Brucella transmitted to animals through fetal secretions, placenta, and vaginal discharges of infected animals and humans by ingesting unpasteurized milk, dairy products, and raw meat. Early detection of B. melitensis is essential for timely intervention and control of the disease. The gold standard diagnostic methods, such as culture, are time-consuming and may take several weeks aiding to the disease spread. Loop-mediated isothermal amplification assay (LAMP) is widely used to detect in...
Source: Current Microbiology - September 22, 2023 Category: Microbiology Authors: Marcia Ashmi Bablu Kumar None Sanjana None Abhishek Deepak Kumar Praveen Singh Source Type: research
Network Analysis of Health-related Behaviors, Insomnia, and Depression Among Urban Left-behind Adolescents in China
This study aims to examine the symptom level associations among multiple health-related behaviors, insomnia, and depression in urban LBA. Data on a sample of urban LBA aged 11-19 (N = 3,601) from the Adolescent Mental Health Survey in Shenzhen, China, were used. Health-related behaviors (i.e., Internet use, physical inactivity, social jetlag, smoking, and alcohol consumption), insomnia, and depressive symptoms were assessed using a self-administered questionnaire. Graphical Gaussian Model (GGM) was used to describe key bridging nodes in an undirected network. Directed Acyclic Graph (DAG) was used to construct a directed ne...
Source: Child Psychiatry and Human Development - September 22, 2023 Category: Child Development Authors: Yifan Zhang Zijuan Ma Wanyi Chen Dongfang Wang Fang Fan Source Type: research
