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Total 5193339 results found since Jan 2013.

Regional disparities in suicide among patients with cancer: A nationwide population-based study in Japan
CONCLUSION: The results demonstrated that patients with cancer in certain prefectures in Japan have a high suicide risk.PMID:37737044 | DOI:10.1002/cam4.6574
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Ken Kurisu Saki Harashima Maiko Fujimori Tatsuo Akechi Kazuhiro Yoshiuchi Yosuke Uchitomi Source Type: research

Fetal Exposure to Preeclampsia and Later Risk of Cardiometabolic Disorders: A Population-Based Cohort Study
CONCLUSIONS: Fetal preeclampsia exposure was associated with adult life hypertension, diabetes, and dyslipidemia, but these associations were likely due to shared etiological factors, rather than exposure to the preeclamptic condition itself.PMID:37737002 | DOI:10.1161/HYPERTENSIONAHA.122.20682
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Abira Paramsothy Tor-Arne Hegvik Anders Engeland Tone Bj ørge Grace M Egeland Kari Klungs øyr Source Type: research

Health equity in action: using community-engaged research to update an intervention promoting a healthy home food environment to Black/African American families
CONCLUSION: The Delphi Technique shows promise as a method for conducting community-engaged research that promotes engagement and identifies key information needed to adapt and implement an existing intervention in a community setting.PMID:37736870 | DOI:10.1007/s10552-023-01753-4
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Debbe Thompson Chishinga Callender Jayna M Dave Maria L Jibaja-Weiss Jane R Montealegre Source Type: research

Oncolytic virus oHSV2 combined with PD-1/PD-L1 inhibitors exert antitumor activity by mediating CD4  + T and CD8 + T cell infiltration in the lymphoma tumor microenvironment
Autoimmunity. 2023 Dec;56(1):2259126. doi: 10.1080/08916934.2023.2259126. Epub 2023 Sep 22.ABSTRACTA novel therapeutic regimen showed that the oncolytic type II herpes simplex virus (oHSV2) was able to prevent colorectal cancer growth, recurrence, and metastasis. However, no study has yet explored whether oHSV2 has an impact on the development of diffuse large B-cell lymphoma (DLBCL). We chose the clinical chemotherapeutic drug doxorubicin (DOX) as a positive control to evaluate the effect of oHSV2 infection on the apoptotic, invasive, and proliferative capacity of DLBCL cells. We next further explored the therapeutic effi...
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Jingbo Zhang Yiwei Guo Huiying Fang Xiuchen Guo Lina Zhao Source Type: research

Correction to: A comparison of two techniques of postoperative analgesia: lignocaine-fentanyl intravenous infusion and ropivacaine-fentanyl epidural infusion in patients undergoing cytoreductive cancer surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)-prospective randomized control study
Langenbecks Arch Surg. 2023 Sep 22;408(1):370. doi: 10.1007/s00423-023-03113-x.NO ABSTRACTPMID:37736776 | DOI:10.1007/s00423-023-03113-x
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Kiran Mahendru Rakesh Garg Sachidanand Jee Bharati Vinod Kumar Nishkarsh Gupta Seema Mishra Sushma Bhatnagar Mukurdipi Ray Suryanarayana Deo Source Type: research

Outcome of cancer patients after atrial fibrillation ablation: Insights from the China-AF registry
CONCLUSIONS: This study suggests that catheter ablation could be feasible for rhythm control of AF patients with concomitant cancer.PMID:37736690 | DOI:10.1111/pace.14830
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Xiaodong Peng Liu He Nian Liu Yanfei Ruan Xin Zhao Xueyuan Guo Wei Wang Songnan Li Ribo Tang Caihua Sang Chenxi Jiang Ronghui Yu Deyong Long Xin Du Jianzeng Dong Changsheng Ma Source Type: research

Argon-helium knife cryoablation plus programmed cell death protein 1 inhibitor in the treatment of advanced soft tissue sarcomas: there is no evidence of the synergistic effects of this combination therapy
CONCLUSION: Cryoablation combined with PD-1 inhibitors in the therapy of advanced STS is safe and can effectively shrink the cryoablation-target lesion. However, there is no evidence of the synergistic effects of this combination therapy.PMID:37736543 | PMC:PMC10509548 | DOI:10.3389/fonc.2023.1185291
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Jiaqiang Wang Dengwei Zong Shuping Dong Shilei Gao Yonghao Yang Peng Zhang Xin Wang Weitao Yao Zhichao Tian Source Type: research

Automated radiosynthesis of < sup > 18 < /sup > FFMPEP- < em > d < /em > < sub > 2 < /sub > for cannabinoid receptor PET imaging
Am J Nucl Med Mol Imaging. 2023 Aug 15;13(4):171-178. eCollection 2023.ABSTRACTThe cannabinoid subtype 1 receptor (CB1R) is highly expressed in the central nervous system and abnormalities in regional CB1R density are associated with neurodegenerative disorders. The PET tracer [18F]FMPEP-d2 is an inverse CB1R agonist which was shown to be suitable for non-invasive PET imaging. In this work, we reported the fully automated radiosynthesis of [18F]FMPEP-d2 on a Synthra RNplus research module. In a total synthesis time of 70 min, [18F]FMPEP-d2 was obtained in 2.2 ± 0.1 GBq (n = 3) with excellent radiochemical and chemical pur...
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Huailei Jiang Yan Guo Otto Muzik Source Type: research

Evaluation of enhanced permeability effect and different linear energy transfer of radionuclides in a prostate cancer xenograft model
In conclusion, we found that specific targeting might negatively influence normal organ uptake when targeting secreted antigens. Furthermore, different energy deposition i.e. linear energy transfer of a radionuclide might have diverse effects on receptor expression and cell proliferation in tumors.PMID:37736493 | PMC:PMC10509292
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Oskar Vilhelmsson Timmermand Marcella Safi Bo Holmqvist Joanna Strand Source Type: research

Chemo-immune cell therapy by intratumoral injection of adoptive NK cells with capecitabine in gastric cancer xenograft model
CONCLUSION: Although NK cell therapy could effectively decrease the mitotic count in vivo, the obtained findings indicated lesser potency than MC despite ex vivo activation. In order to enhance NK cell therapy effectiveness, suppressive features of the tumor microenvironment and inhibitory immune checkpoints blockade should be considered.PMID:37736341 | PMC:PMC10509737 | DOI:10.34172/bi.2022.26386
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Zeinab Ghazvinian Shahrokh Abdolahi Mohammad Ahmadvand Amir Hossein Emami Samad Muhammadnejad Hamid Asadzadeh Aghdaei Jafar Ai Mohammad Reza Zali Iman Seyhoun Javad Verdi Kaveh Baghaei Source Type: research

Cytotoxicity of WT1-reactive T cells against Wilms tumor: An implication for antigen-specific adoptive immunotherapy
CONCLUSION: WT1-reactive T cells can be effectively enriched from the PBMCs of patients with Wilms tumor. Ex vivo generated WT1-reactive T cells might be considered an adoptive immunotherapeutic option for WT1+ Wilms tumors.PMID:37736339 | PMC:PMC10509739 | DOI:10.34172/bi.2023.27576
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Seyed Mostafa Monzavi Amir Ali Hamidieh Mohammad Vasei Jafar Ai Naser Ahmadbeigi Hamid Arshadi Samad Muhammadnejad Abdol-Mohammad Kajbafzadeh Source Type: research

Teleoperated and Automated Control of a Robotic Tool for Targeted Prostate Biopsy
J Med Robot Res. 2023 Mar-Jun;8(1-amp 2):2340002. doi: 10.1142/s2424905x23400020. Epub 2023 Mar 18.ABSTRACTThis work presents a robotic tool with bidirectional manipulation and control capabilities for targeted prostate biopsy interventions. Targeted prostate biopsy is an effective image-guided technique that results in detection of significant cancer with fewer cores and lower number of unnecessary biopsies compared to systematic biopsy. The robotic tool comprises of a compliant flexure section fabricated on a nitinol tube that enables bidirectional bending via actuation of two internal tendons, and a biopsy mechanism for...
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Blayton Padasdao Samuel Lafreniere Mahsa Rabiei Zolboo Batsaikhan Bardia Konh Source Type: research

Activity of pazopanib in < em > EWSR1-NFATC2 < /em > translocation-associated bone sarcoma
Oncoscience. 2023 Sep 20;10:44-53. doi: 10.18632/oncoscience.587. eCollection 2023.ABSTRACTPazopanib is a multi-kinase inhibitor that is currently approved for treatment of advanced renal cell carcinoma and chemotherapy-refractory soft tissue sarcoma. In this case report, we discuss the case of a patient with a EWSR1-NFATC2 fusion positive bone sarcoma who had exceptional tumor control through using pazopanib and surgery for an overall duration exceeding 5 years. We also review the literature on EWSR1-NFATC2 translocation-associated sarcomas and use of pazopanib in bone sarcomas.PMID:37736255 | PMC:PMC10511123 | DOI:10.18632/oncoscience.587
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Mohamed A Gouda Maria A Zarzour Ara A Vaporciyan Kalevi Kairemo Hubert H Chuang Vivek Subbiah Source Type: research

Multi-disciplinary management of recurrent gastrointestinal stromal tumor harboring KIT exon 11 mutation with the switch-control kinase inhibitor ripretinib and surgery
Oncoscience. 2023 Sep 20;10:38-43. doi: 10.18632/oncoscience.586. eCollection 2023.ABSTRACTRipretinib is a tyrosine kinase inhibitor that was approved by the United States FDA in 2020 for treatment of advanced gastrointestinal stromal tumor (GIST) in patients who received prior treatment with three or more tyrosine kinase inhibitors. In this case report, we show the durable clinical benefit achieved in a patient with GIST by using ripretinib and repeated timely surgical resection of limited disease progression. The total time on ripretinib was 43 months which is longer than the current reported data from ripretinib clinica...
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Mohamed A Gouda Filip Janku Neeta Somaiah Kelly K Hunt Sireesha Yedururi Vivek Subbiah Source Type: research

Use of a Person-Centered Narrative Intervention in an Outpatient Palliative Care Setting: A Feasibility Study
J Patient Exp. 2023 Sep 18;10:23743735231202729. doi: 10.1177/23743735231202729. eCollection 2023.ABSTRACTPerson-centered narrative interventions offer potential solutions to facilitate a connection between the person receiving care and the person delivering the care, to improve quality of care, and positively impact a patient's biopsychosocial well-being. This single-arm feasibility study investigates patient-reported outcomes and barriers/facilitators to the implementation of an all-virtually delivered person-centered narrative intervention into the person's electronic health record. Overall, electronic data collection f...
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Heather Coats Nadia Shive C Robert Bennett Bonnie Adrian Andrew D Boyd Ardith Z Doorenbos Sarah J Schmiege Source Type: research