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Infectious Disease: Tuberculosis

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Effect of gaseous pollutant and greenness exposure on mortality during treatment of newly treated tuberculosis patients: a provincial population-based cohort study
CONCLUSION: Gaseous pollutants are a risk factor during the treatment of newly treated TB patients and greenness exposure is a protective factor. Higher greenness exposure reduces the risk of death due to exposure to gaseous pollutants.PMID:37608175 | DOI:10.1007/s11356-023-29256-4
Source: Environmental Science and Pollution Research International - August 22, 2023 Category: Environmental Health Authors: Jia-Wen Zhao Xin-Qiang Wang Zhen-Hua Li Yi-Cheng Mao Sun Zhang Kai Huang Cheng-Yang Hu Xiu-Jun Zhang Xiao-Hong Kan Source Type: research

Heterogeneity of Mycobacterium tuberculosis Strains Circulating in Panama's Western Region
Am J Trop Med Hyg. 2023 Aug 21:tpmd230039. doi: 10.4269/ajtmh.23-0039. Online ahead of print.ABSTRACTTuberculosis remains a challenge in both rural and urban areas. Although a majority of countries display a higher burden in urban areas compared with rural areas, Panama continues to report the highest mortality rate in Central America. Urban areas, such as Panama City, report a high tuberculosis burden, whereas Panama's western region, including the provinces of Chiriquí, Bocas del Toro (both semiurban) and Ngäbe-Bugle (rural), show a lower burden. We aimed to identify highly transmitted Mycobacterium tuberculosis strain...
Source: The American Journal of Tropical Medicine and Hygiene - August 21, 2023 Category: Tropical Medicine Authors: Fermin Acosta Ricardo Salda ña Sara Miranda Daniela Candanedo Dilcia Sambrano Mitchelle Mor án Saily Bejarano Yeraldine De Arriba Angel Reigosa Elizabeth De Dixon Mar ía Atencio Ram ón Castillo Amador Goodridge Source Type: research

Etiologic Investigation of Patients Diagnosed with Bacteriologically Unconfirmed Tuberculosis in Tanzania
Am J Trop Med Hyg. 2023 Aug 21:tpmd230023. doi: 10.4269/ajtmh.23-0023. Online ahead of print.ABSTRACTGlobally, half of patients with pulmonary tuberculosis (PTB) are diagnosed clinically without bacteriologic confirmation. In clinically diagnosed PTB patients, we assessed both the proportion in whom PTB could be bacteriologically confirmed by reference standard diagnostic tests and the prevalence of diseases that mimic PTB. We recruited adult patients beginning treatment of bacteriologically unconfirmed PTB in Moshi, Tanzania, in 2019. We performed mycobacterial smear, Xpert MTB/RIF Ultra, and mycobacterial culture, fungal...
Source: The American Journal of Tropical Medicine and Hygiene - August 21, 2023 Category: Tropical Medicine Authors: Michael J Maze Gissela Nyakunga Philoteus A Sakasaka Kajiru G Kilonzo Elisha Luhwago Manase Chelangwa John A Crump Riziki M Kisonga Deng B Madut Josephine Rogath Adnan Sadiq Rennae Thiessen Matthew P Rubach Source Type: research

Heterogeneity of Mycobacterium tuberculosis Strains Circulating in Panama's Western Region
Am J Trop Med Hyg. 2023 Aug 21:tpmd230039. doi: 10.4269/ajtmh.23-0039. Online ahead of print.ABSTRACTTuberculosis remains a challenge in both rural and urban areas. Although a majority of countries display a higher burden in urban areas compared with rural areas, Panama continues to report the highest mortality rate in Central America. Urban areas, such as Panama City, report a high tuberculosis burden, whereas Panama's western region, including the provinces of Chiriquí, Bocas del Toro (both semiurban) and Ngäbe-Bugle (rural), show a lower burden. We aimed to identify highly transmitted Mycobacterium tuberculosis strain...
Source: Rural Remote Health - August 21, 2023 Category: Rural Health Authors: Fermin Acosta Ricardo Salda ña Sara Miranda Daniela Candanedo Dilcia Sambrano Mitchelle Mor án Saily Bejarano Yeraldine De Arriba Angel Reigosa Elizabeth De Dixon Mar ía Atencio Ram ón Castillo Amador Goodridge Source Type: research

Bacterial dissemination in < em > Mycobacterium tuberculosis < /em > by CD+ T-cells & amp; proinflammatory cytokines
CONCLUSIONS: Our findings imply that increased bacilli in the spleen at the 8th wk of infection may be caused by the overexpression of CD4+ T-cell lymphocyte subsets and cytokines that generated inflammation during the 4th wk of infection. This is a pilot study with a small sample size and less assertive inference. Larger studies would be helpful to validate the results of the present investigation.PMID:37602585 | DOI:10.4103/ijmr.ijmr_2143_21
Source: Indian J Med Res - August 21, 2023 Category: Research Authors: Kusuma Sai Davuluri Shoor Vir Singh D S Chauhan Source Type: research

Heterogeneity of Mycobacterium tuberculosis Strains Circulating in Panama's Western Region
Am J Trop Med Hyg. 2023 Aug 21:tpmd230039. doi: 10.4269/ajtmh.23-0039. Online ahead of print.ABSTRACTTuberculosis remains a challenge in both rural and urban areas. Although a majority of countries display a higher burden in urban areas compared with rural areas, Panama continues to report the highest mortality rate in Central America. Urban areas, such as Panama City, report a high tuberculosis burden, whereas Panama's western region, including the provinces of Chiriquí, Bocas del Toro (both semiurban) and Ngäbe-Bugle (rural), show a lower burden. We aimed to identify highly transmitted Mycobacterium tuberculosis strain...
Source: Am J Trop Med Hyg - August 21, 2023 Category: Infectious Diseases Authors: Fermin Acosta Ricardo Salda ña Sara Miranda Daniela Candanedo Dilcia Sambrano Mitchelle Mor án Saily Bejarano Yeraldine De Arriba Angel Reigosa Elizabeth De Dixon Mar ía Atencio Ram ón Castillo Amador Goodridge Source Type: research

Etiologic Investigation of Patients Diagnosed with Bacteriologically Unconfirmed Tuberculosis in Tanzania
Am J Trop Med Hyg. 2023 Aug 21:tpmd230023. doi: 10.4269/ajtmh.23-0023. Online ahead of print.ABSTRACTGlobally, half of patients with pulmonary tuberculosis (PTB) are diagnosed clinically without bacteriologic confirmation. In clinically diagnosed PTB patients, we assessed both the proportion in whom PTB could be bacteriologically confirmed by reference standard diagnostic tests and the prevalence of diseases that mimic PTB. We recruited adult patients beginning treatment of bacteriologically unconfirmed PTB in Moshi, Tanzania, in 2019. We performed mycobacterial smear, Xpert MTB/RIF Ultra, and mycobacterial culture, fungal...
Source: Am J Trop Med Hyg - August 21, 2023 Category: Infectious Diseases Authors: Michael J Maze Gissela Nyakunga Philoteus A Sakasaka Kajiru G Kilonzo Elisha Luhwago Manase Chelangwa John A Crump Riziki M Kisonga Deng B Madut Josephine Rogath Adnan Sadiq Rennae Thiessen Matthew P Rubach Source Type: research

Bacterial dissemination in < em > Mycobacterium tuberculosis < /em > by CD+ T-cells & amp; proinflammatory cytokines
CONCLUSIONS: Our findings imply that increased bacilli in the spleen at the 8th wk of infection may be caused by the overexpression of CD4+ T-cell lymphocyte subsets and cytokines that generated inflammation during the 4th wk of infection. This is a pilot study with a small sample size and less assertive inference. Larger studies would be helpful to validate the results of the present investigation.PMID:37602585 | DOI:10.4103/ijmr.ijmr_2143_21
Source: The Indian Journal of Medical Research - August 21, 2023 Category: Biomedical Science Authors: Kusuma Sai Davuluri Shoor Vir Singh D S Chauhan Source Type: research

Latent Tuberculosis Infection in Users of Drug Dependence Care and Follow-up Centers in Barcelona in 2017-2021: A Cross-sectional Descriptive Study
CONCLUSIONS: This study improves TB control and highlights the need for this LTBI control program in CASs.PMID:37599795 | PMC:PMC10432789 | DOI:10.1016/j.opresp.2023.100257
Source: Respiratory Care - August 21, 2023 Category: Respiratory Medicine Authors: Raquel Prieto Garc ía Joan Pau Millet David Palma Mar ía Gabriela Barbaglia Navarro Cristina Rius Gibert Barcelona CAS Working Group Source Type: research

Bacterial dissemination in < em > Mycobacterium tuberculosis < /em > by CD+ T-cells & amp; proinflammatory cytokines
CONCLUSIONS: Our findings imply that increased bacilli in the spleen at the 8th wk of infection may be caused by the overexpression of CD4+ T-cell lymphocyte subsets and cytokines that generated inflammation during the 4th wk of infection. This is a pilot study with a small sample size and less assertive inference. Larger studies would be helpful to validate the results of the present investigation.PMID:37602585 | DOI:10.4103/ijmr.ijmr_2143_21
Source: The Indian Journal of Medical Research - August 21, 2023 Category: Biomedical Science Authors: Kusuma Sai Davuluri Shoor Vir Singh D S Chauhan Source Type: research

Latent Tuberculosis Infection in Users of Drug Dependence Care and Follow-up Centers in Barcelona in 2017-2021: A Cross-sectional Descriptive Study
CONCLUSIONS: This study improves TB control and highlights the need for this LTBI control program in CASs.PMID:37599795 | PMC:PMC10432789 | DOI:10.1016/j.opresp.2023.100257
Source: Respiratory Care - August 21, 2023 Category: Respiratory Medicine Authors: Raquel Prieto Garc ía Joan Pau Millet David Palma Mar ía Gabriela Barbaglia Navarro Cristina Rius Gibert Barcelona CAS Working Group Source Type: research

Clinical Characteristics of Tracheobronchopathia Osteochondroplastica: A Retrospective Study of 33 Patients
CONCLUSION: TO is a slowly progressing disease with non-specific clinical symptoms and a low positive rate of imaging diagnosis, making it susceptible to misdiagnosis and missed diagnosis. The disease needs to be diagnosed by combining imaging features, fiberoptic bronchoscopy, and pathological findings.PMID:37601808 | PMC:PMC10438451 | DOI:10.2147/IJGM.S418394
Source: Cancer Control - August 21, 2023 Category: Cancer & Oncology Authors: Qiliang Liu Yan Hu Mei Lei Chunlin Mei Chengqing Yang Source Type: research